Zobrazeno 1 - 10
of 145
pro vyhledávání: '"J. Van Der Kaay"'
Autor:
L. Chimsuku, F. H. Verhoeff, S. M. Maxvell, R. L. Broadhead, A. Thomas, H. J. Van der Kaay, W. Russell, B. Brabin
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 89, Pp 1-2 (1994)
Preliminary results are presented from this study which indicate that 84.8 of pregnant women present at first antenatal visit with anemia (Hb 11g/dl) an 8.7 of their infants (n = 230) have a hemoglobin at birth below 14g/dl. There is an association b
Externí odkaz:
https://doaj.org/article/a623ca0c84c0441dbf1a371a6f843ace
Publikováno v:
Biochemical Society Transactions. 35:188-192
The lipid phosphatase, PTEN (phosphatase and tensin homologue deleted on chromosome 10), is the product of a major tumour suppressor gene that antagonizes PI3K (phosphoinositide 3-kinase) signalling by dephosphorylating the 3-position of the inositol
Autor:
Brian A. Hemmings, Nicholas K. Tonks, C P Downes, Javor P. Stolarov, J. Van Der Kaay, Michael Wigler, I. Pass, Michael P. Myers, Ian H. Batty
Publikováno v:
Proceedings of the National Academy of Sciences. 95:13513-13518
Since their discovery, protein tyrosine phosphatases have been speculated to play a role in tumor suppression because of their ability to antagonize the growth-promoting protein tyrosine kinases. Recently, a tumor suppressor from human chromosome 10q
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 55:131-137
Following a striking increase in the severity of autumnal outbreaks of Plasmodium falciparum during the last decade in the Northwest Frontier Province (NWFP) of Pakistan, the role of climatologic variables was investigated. A multivariate analysis sh
Autor:
P. J. M. Van Haastert, J. C. T. Bergsma, J. Van Der Kaay, P. Van Dijken, B. De Vries, H. S. Hiemstra
Publikováno v:
Biochemical Journal. 314:491-495
The small ion lithium, a very effective agent in the treatment of manic depressive patients, inhibits the mammalian enzyme inositol monophosphatase, which is proposed as the biological target for the effects of lithium. In this study we investigated
Publikováno v:
Biochemical Journal. 312:911-917
Although many cells contain large amounts of InsP6, its metabolism and function is still largely unknown. In Dictyostelium lysates, the formation of InsP6 by sequential phosphorylation of inositol via Ins(3,4,6)P3 has been described [Stevens and Irvi
Publikováno v:
The EMBO Journal. 13:1601-1609
The micro-organism Dictyostelium uses extracellular cAMP to induce chemotaxis and cell differentiation. Signals are transduced via surface receptors, which activate G proteins, to effector enzymes. The deduced protein sequence of Dictyostelium discoi
Autor:
H.J.H. Klever, Bernard J. Brabin, A.M.C. Witte, T. A. Eggelte, Michael P. Alpers, H. J. Van Der Kaay
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 84:521-525
The evaluation of an enzyme-linked immunosorbent assay (ELISA) for chloroquine and its metabolites in blood, urine and breast-milk is reported. ELISA blood levels, following standard treatment with chloroquine of pregnant and non-pregnant women, show
Publikováno v:
Parasitology Research. 76:526-530
An improved direct agglutination test (DAT) is assessed for the detection of Leishmania infantum antibodies in man and in the canine reservoir in Southern France. The test performance in 32 human visceral leishmaniasis patients was in agreement with
Autor:
T.R. Burkot, Michael P. Alpers, Gregory Crane, Loretta Brabin, H. J. Van Der Kaay, Karen P. Forsyth, Bernard J. Brabin
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 84:40-45
The objective of this study was to determine the prevalence of antibodies recognizing the circumsporozoite (CS) protein of Plasmodium by an enzyme-linked immunosorbent assay, in 2 subpopulations of women with significantly different enlarged spleen r