Zobrazeno 1 - 10
of 92
pro vyhledávání: '"J. V. Forrester"'
Autor:
C. Mölzer, Y.-H. Liu, E. Muckersie, I. P. Klaska, R. Cornall, H. M. Wilson, L. Kuffová, J. V. Forrester
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Undifferentiated uveitis (intraocular inflammation, IOI) is an idiopathic sight-threatening, presumed autoimmune disease, accountable for ~ 10% of all blindness in the developed world. We have investigated the association of uveitis with inf
Externí odkaz:
https://doaj.org/article/9f6ad15b9cbd4026aa9b4100668b749c
Publikováno v:
The Journal of Immunology. 159:5132-5142
The production of large amounts of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) has been described as a double-edged sword eliciting pro- or anti-inflammatory effects in different immune situations. Our aim, therefore, was to investiga
Publikováno v:
The Journal of Immunology. 156:3696-3703
The alternative CD2-mediated pathway of T cell activation, which is independent of MHC/peptide recognition by the TCR/CD3 complex, is dependent upon two signals being received by the CD2 molecule. The natural ligand for CD2 is CD58, but controversy e
Autor:
D. E. Wallace, G. T. McGreal, G. C. O’Toole, G. P. Holloway, E. McDermott, J. Blake, D. J. Kilmartin, J. V. Forrester, A. D. Dick, V. J. Marmion, R. Brennan, G. Williams, C. Keohane, M. O’Shaughnessy, G. O’Connor, P. Tormey, K. A. Mirza, F. A. Qazi, A. Maloney, S. V. Raman, K. R. Kumar, B. J. Young, A. Bobart, S. Fenton, H. Cassidy, M. Fenton, L. Cassidy, R. Sterling, K. May, R. M. L. Doran
Publikováno v:
Irish Journal of Medical Science. 167:118-120
Publikováno v:
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. 99(9)
The severity of disease and the side-effects of long-term corticosteroid treatment support the rationale for other immunosuppressive drugs in the management of uveitis. Mycophenolate mofetil (MMF) is a selective inhibitor of ionosine monophosphate de
Autor:
L, Kuffová, L, Lumsden, V, Veselá, J A, Taylor, M, Filipec, V, Holán, A D, Dick, J V, Forrester
Publikováno v:
Transplantation. 72(7)
Little information exists on the trafficking of myeloid and lymphoid cells between the transplanted cornea and the secondary lymphoid tissue. This study reports on changes in the cornea and the draining lymph node (DLN) from the time of graft emplace
Publikováno v:
Investigative ophthalmologyvisual science. 42(7)
To determine the location of the CC chemokines macrophage inflammatory protein (MIP)-1alpha, monocyte chemoattractant protein (MCP)-1, and regulated on activation of normal T-cell-expressed and secreted (RANTES) during disease progression in experime
Publikováno v:
Investigative ophthalmologyvisual science. 42(6)
To assess the effects of mycophenolate mofetil (MMF) therapy on T helper cell activation status, using CD69 expression and cytokine profile with flow cytometry in relation to clinical activity in uveitis.Patients with posterior or intermediate uveiti
Publikováno v:
Investigative ophthalmologyvisual science. 42(1)
Interleukin (IL)-18 has been described as a proinflammatory cytokine in rheumatoid arthritis and bacterial infectious diseases. The present study was designed to determine the role of IL-18 in a model of ocular experimental autoimmune uveitis (EAU).
Publikováno v:
The British journal of ophthalmology. 84(9)
AIMS To describe management and clinical outcomes of serpiginous choroidopathy treated primarily with cyclosporin at a tertiary uveitis referral centre METHODS A case series of 14 eyes of seven patients with serpiginous choroidopathy with follow up r