Zobrazeno 1 - 10 of 30 pro vyhledávání: '"J. V. BRUCKNER"'
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Effect of oral dosing vehicles on the subchronic hepatotoxicity of carbon tetrachloride in the rat
Autor: K P Koporec, J V Bruckner, Hyo J. Kim, W F MacKenzie
Publikováno v: Journal of Toxicology and Environmental Health. 44:13-27
Previous studies in this laboratory have shown that corn oil delayed and prolonged the gastrointestinal absorption of carbon tetrachloride (CCl4) and reduced its acute hepatotoxicity in rats. The objective of the present study was to extend the durat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e0517ae3b51089ec7ee748a2db178e
https://doi.org/10.1080/15287399509531940
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5
Distribution of cardiac output during diurnal changes of activity in rats
Autor: Robert B. Armstrong, Michael D. Delp, R. O. Manning, J. V. Bruckner
Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 261:H1487-H1493
Rat locomotor and feeding behavior varies on a diurnal basis; at night the animals actively forage and eat, whereas during the day they are more inactive and somnolent. At night, cardiac output is higher, presumably for enhanced perfusion of the acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c985b8a7a7ad28ced87e2eb522a68e35
https://doi.org/10.1152/ajpheart.1991.261.5.h1487
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6
Organ weights and fat volume in rats as a function of strain and age
Autor: S Muralidara, J E Simmons, D J Schoeffner, D A Warren, J V Bruckner
Publikováno v: Journal of toxicology and environmental health. Part A. 56(7)
The Fischer 344 (F344) rat and the Sprague-Dawley (SD) rat are used commonly to evaluate potential adverse health effects resulting from environmental exposure to chemicals. They are also the most common rat strain/stock used in physiologically based
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848bfb42e95352bd31db8a21b4c18b99
https://pubmed.ncbi.nlm.nih.gov/10201633
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7
A comprehensive evaluation of the vial equilibration method for quantification of the metabolism of volatile organic chemicals. Trichloroethylene
Autor: C, Kim, R O, Manning, R P, Brown, J V, Bruckner
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 22(6)
A study was undertaken, using 1,1,2-trichloroethylene (TCE), to: a) evaluate and improve the efficiency of the vial equilibration method, as first reported by Sato and Nakajima (Toxicol. Appl. Pharmacol. 47, 41-46, 1979); b) select an appropriate veh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ce85b678b689885ae00c773deed8e92
https://pubmed.ncbi.nlm.nih.gov/7895602
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8
Metabolism and disposition of sulfluramid, a unique polyfluorinated insecticide, in the rat
Autor: R O, Manning, J V, Bruckner, M E, Mispagel, J M, Bowen
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 19(1)
The objectives of this study were to characterize the absorption, distribution, and elimination of sulfluramid (N-ethyl perfluorooctane sulfonamide) and its major metabolite, perfluorooctane sulfonamide (DESFA), in order to assess the effect of dosag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e354ab857ee6c474bfb259fe84e30925
https://pubmed.ncbi.nlm.nih.gov/1673400
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