Three-Year, Randomized, Sham-Controlled Trial of Dexamethasone Intravitreal Implant in Patients with Diabetic Macular Edema

Autor: David S. Boyer, 1 Young Hee Yoon, MD, PhD, 2 Rubens Belfort, Jr, MD, PhD, 3 Francesco Bandello, 4 Raj K. Maturi, 5 Albert J. Augustin, 6 Xiao Yan Li, 7 Harry Cui, 7 Yehia Hashad, 7 Scott M. Whitcup, MDThe MEAD Study Group Principal Investigators: Suel Abujamra, James Acton, Fareed Ali, Andrew Antoszyk, Albert J. Augustin, Carl C. Awh, Adiel Barak, Karl Ulrich Bartz Schmidt, Caroline R. Baumal, Rubens Belfort, J.r., Muna Bhende, William Z. Bridges, David M. Brown, Trevor Carmichael, Ken Carnevale, Antonio M. Casella, Tom Chang, Daniel Chechik, San Ni Chen, Lawrence P. Chong, Victor Chong, Joel Corwin, Catherine Creuzot Garcher, Alan Cruess, Mark Daniell, Marcos P. de Avila, Haroldo Vieira de Moraes, Robert G. Devenyi, Bernard H. Doft, Mark Donaldson, Richard Dreyer, Dean Eliott, Harry M. Engel, Jan Ernest, Thomas F. Essman, Philip M. Falcone, Sharon Fekrat, Joseph R. Ferencz, Joao L. Ferreira, Joao Figueira, Ivan Fiser, Bradley Foster, Gregory M. Fox, William R. Freeman, S. P. Garg, Mark Gillies, David Glaser, Burton G. Goldstein, Andre M. V. Gomes, John R. Gonder, Lingam Gopal, Petrus Gous, Amod Gupta, Anurag Gupta, Lawrence Halperin, Dennis Han, Seenu M. Hariprasad, Frank G. Holz, Peter Kaiser, Bohdana Kalvodova, Barrett Katz, Randy S. Katz, Dariusz Kecik, Judianne Kellaway, Itamar Klemperer, Baruch Kuppermann, Paolo Lanzetta, Rosangela Lattanzio, Won Ki Lee, John Lehr, Monique Leys, Isaac Loose, Andrew Lotery, Da Wen Lu, Paul McCartney, Ajit B. Majji, Jose A. Martinez, Pascale Massin, Raj K. Maturi, Ugo Menchini, Geeta Menon, Mark Michels, Edoardo Midena, James Miller, Paul Mitchell, Joseph Moisseiev, Lawrence Morse, Rafael Navarro, Janos Nemeth, Henry Newland, Richard Newsom, John Nichols, Juan Orellana, Nicola Orzalesi, Augusto Paranhos, Robert Park, Susanna Park, Maurizio Battaglia Parodi, Peter R. Pavan, James Peace, Don J. Perez Ortiz, Ayala Pollack, Kim Ramaswamy, Ramakrishna Ratnakaram, Giuseppe Ravalico, Jiri Rehak, Kourous Rezaei, Stanislao Rizzo, Francisco J. Rodriguez Alvira, Jean Paul Romanet, Steven Rose, Richard B. Rosen, Luca Rossetti, Jose Maria Ruiz Moreno, SriniVas Sadda, Kenneth Sall, Dirk Sandner, Alvaro Fernandez Vega Sanz, Gil Sartani, Stefanie Schmickler, Steven D. Schwartz, Y. R. Sharma, Shwu Jiuan Sheu, Michael Singer, Sobha Sivaprasad, Gisele Soubrane, Petr Soucek, Eric H. Souied, Giovanni Staurenghi, Jan Studnicka, Marta Suarez Figueroa, Walter Y. Takahashi, Patrick L. Tsai, Lawrence J. Ulanski, Harvey Uy, Monica Varano, Miroslav Veith, Igor Vicha, Francesco Viola, Linda Visser, Dov Weinberger, Glenn L. Wing, Edmund Wong, Tien Wong, Edward Wylegala, Jiong Yan, Young Hee Yoon, Lucy H. Young, Hyeong G. Yu, Ingrid E. Zimmer Galler, TOGNETTO, DANIELE

Publikováno v: Ozurdex MEAD Study Group & Newsom, R B 2014, ' Three-year, randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with diabetic macular edema ', Ophthalmology, vol. 121, no. 10, pp. 1904-1914 . https://doi.org/10.1016/j.ophtha.2014.04.024

Purpose: To evaluate the safety and efficacy of dexamethasone intravitreal implant (Ozurdex, DEX implant) 0.7 and 0.35 mg in the treatment of patients with diabetic macular edema (DME).Design: Two randomized, multicenter, masked, sham-controlled, pha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac6868a174f5dad2c622dd901451a00
https://doi.org/10.1016/j.ophtha.2014.04.024

Resveratrol Based Oral Nutritional Supplement Produces Long-Term Beneficial Effects on Structure and Visual Function in Human Patients

Autor: Luke Miller, Lawrence J. Ulanski, Shivani Sockanathan, Stuart Richer, Carla Podella, Shana Patel

Publikováno v: Nutrients, Vol 6, Iss 10, Pp 4404-4420 (2014)
Nutrients

Background: Longevinex® (L/RV) is a low dose hormetic over-the-counter (OTC) oral resveratrol (RV) based matrix of red wine solids, vitamin D3 and inositol hexaphosphate (IP6) with established bioavailability, safety, and short-term efficacy against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43fa7a94828e09aef9ef692aa66748f
http://www.mdpi.com/2072-6643/6/10/4404

Novel, Low-Cost, Highly Soluble n-Type Semiconductors: Tetraazaanthracene Tetraesters

Autor: E. Bartnik, Tomasz Marszalek, Malgorzata Zagorska, M. Kucinska, Pawel Gawrys, J. Ulanski

Publikováno v: Organic Letters

New tetraester derivatives of 1,4,5,8-tetraazaanthracene have been prepared and characterized by spectroscopic and electrochemical techniques. The LUMO level of the compounds is close to -4 eV (the so-called air operating stability border in n-channe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff0ee89041b62ff6f92375923d49d54
https://doi.org/10.1021/ol2025789

Blood–brain barrier mechanisms involved in brain calcium and potassium homeostasis

Autor: Jianming Xiang, A. Lorris Betz, Steven R. Ennis, Lawrence J. Ulanski, Richard F. Keep

Publikováno v: Brain Research. 815:200-205

This study examined the potential roles of the plasma membrane Ca2+-ATPase (PMCA) at the blood-CSF and blood-brain barriers in brain Ca2+ homeostasis and blood-brain barrier Na+/K+-ATPase subunits in brain K+ homeostasis. During dietary-induced hypo-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9d3a530a0e362baa7005202a0e03c8
https://doi.org/10.1016/s0006-8993(98)01155-x

Thin chemically anisotropic polyporphyrin films with potential application in nonlinear optics

Autor: M Kryszewski, J Ulanski

Publikováno v: Pure and Applied Optics: Journal of the European Optical Society Part A. 7:211-220

Following our studies on anisotropic polymer films, we have investigated the interfacial polymerization of porphyrins bearing functional groups (e.g. amine and acid chloride or carbonyl and hydroxyl groups) which leads to thin films which have an asy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ff18def1c03068f64c581f6d4cced5b
https://doi.org/10.1088/0963-9659/7/2/011