Safety, immunogenicity, and efficacy of a Plasmodium falciparum vaccine comprising a circumsporozoite protein repeat region peptide conjugated to Pseudomonas aeruginosa toxin A

Autor: J C Beier, Gary W. Long, I Schneider, S.J. Cryz, D. M. Gordon, Louis Fries, J U Que, M Gross, J. C. Sadoff

Publikováno v: Infection and Immunity. 60:1834-1839

Twenty-one malaria-naive volunteers were immunized with a vaccine consisting of a 22-kDa recombinant peptide (R32LR), derived from the repeat region of Plasmodium falciparum circumsporozoite (CS) protein, covalently coupled to detoxified Pseudomonas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6deffb22309f3f5158d5b14eebb143
https://doi.org/10.1128/iai.60.5.1834-1839.1992

Hypothesis: How Streptomycin Treatment Compromises Colonisation Resistance Against Enteric Pathogens in Mice

Autor: J. U. Que, P. Pongpech, D. J. Hentges

Publikováno v: Microbial Ecology in Health and Disease; Vol 3, No 3 (1990)

One week after administration of streptomycin to Swiss white mice, caecal flora composition was altered but total populations of cultivable aerobes and anaerobes were unchanged. However, microscopic estimation of numbers demonstrated a 100-fold decre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6338679245c7b308c53fc7206ad2b59c
https://doi.org/10.3109/08910609009140124

Safety and immunogenicity of a Haemophilus influenzae type B polysaccharide-tetanus toxoid conjugate vaccine combined with diphtheria, tetanus and pertussis vaccines in Thai infants

Autor: T, Chotpitayasunondh, C, Panpitpat, U, Thisyakorn, E, Furer, J U, Que, T, Hasler, S J, Cryz

Publikováno v: The Southeast Asian journal of tropical medicine and public health. 28(1)

A randomized, open, multicenter trial was conducted to determine the safety and immunogenicity of a Haemophilus influenzae type b polysaccharide-tetanus toxoid (PRP-T) conjugate vaccine combined with tetanus, diphtheria and pertussis (DTP) vaccine in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a0c91fff5ea8a56ff3e3a4c5c09483b
https://pubmed.ncbi.nlm.nih.gov/9322290

Immunization of Noncolonized Cystic Fibrosis Patients against Pseudomonas aeruginosa

Autor: Urs B. Schaad, Joanna Wedgwood, Anna Ruedeberg, Stanley J. Cryz, Emil Fürer, Alois B. Lang, J. U. Que

Publikováno v: Cryz, Stanley J.; Wedgwood, Joanna; Lang, Alois B.; Ruedeberg, Anna; Que, J. U.; Fürer, Emil; Schaad, Urs B. (1994). Immunization of Noncolonized Cystic Fibrosis Patients against Pseudomonas aeruginosa. Journal of infectious diseases, 169(5), pp. 1159-1162. The University of Chicago Press 10.1093/infdis/169.5.1159

The long-term safety and immunogenicity of a polyvalent Pseudomonas aeruginosa conjugate vaccine was evaluated in 30 noncolonized cystic fibrosis patients. Four doses were administered over 3 years, and patients were followed for a mean of 38 months.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa3fe2ef945625be4093b155f62ae87
https://boris.unibe.ch/115074/1/169-5-1159.pdf

Safety and immunogenicity of Pseudomonas aeruginosa conjugate A vaccine in cystic fibrosis

Autor: J. U. Que, Stanley J. Cryz, Anna Ruedeberg, Alois B. Lang, E. Fürer, Joanna Wedgwood, U. B. Schaad

Publikováno v: Lancet (London, England). 338(8777)

To assess the safety and immunogenicity of a Pseudomonas aeruginosa octavalent 0-polysaccharide-toxin A conjugate vaccine, 22 patients (mean age 7 years) with cystic fibrosis who had no history of colonisation with P aeruginosa were immunised with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1df2879e053d762760d01f3fc0beeb
https://pubmed.ncbi.nlm.nih.gov/1682645