Zobrazeno 1 - 10
of 58
pro vyhledávání: '"J. Troke"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 41:1002-1006
The products arising from the intra-molecular acyl migration reactions of drug ester glucuronides can be reactive towards cellular proteins and have been proposed to cause toxic side effects. The relative reactivity of a range of drug and model glucu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b122ab1e78dc0c6864db34ca4733267
https://doi.org/10.1016/j.jpba.2006.01.006
https://doi.org/10.1016/j.jpba.2006.01.006
Publikováno v:
Chemical Research in Toxicology. 14:1363-1370
A widely held view in drug metabolism and pharmacokinetic studies is that the initial 1-isomer to 2-isomer step in the intramolecular acyl migration of drug ester glucuronides is irreversible, and that alpha-1-O-acyl isomers do not occur under physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa609106999814966db2fc5737b23629
https://doi.org/10.1021/tx010015q
https://doi.org/10.1021/tx010015q
Publikováno v:
Scopus-Elsevier
The pathways of biotransformation of 4-fluorobiphenyl (4FBP) by the ectomycorrhizal fungus Tylospora fibrilosa and several other mycorrhizal fungi were investigated by using 19 F nuclear magnetic resonance (NMR) spectroscopy in combination with 14 C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725d20ab016e7834d0b6e504d2bd51be
https://doi.org/10.1128/aem.65.9.4021-4027.1999
https://doi.org/10.1128/aem.65.9.4021-4027.1999
Publikováno v:
Chemosphere. 38:1085-1101
The incubation of the model pollutant [U-14C]′-4-fluorobiphenyl (4FBP) in soil, in the presence and absence of biphenyl (a co-substrate), was carried out in order to study the qualitative disposition and fate of the compound using 14C-HPLC and 19F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf556c1e21647a9423970746377fbe7
https://doi.org/10.1016/s0045-6535(98)00351-8
https://doi.org/10.1016/s0045-6535(98)00351-8
Publikováno v:
ACS nano. 2(5)
Cancer and many other diseases are characterized by changes in cell morphology, motion, and mechanical rigidity. However, in live cell cytology, stimulus-induced morphologic changes typically take 10-30 min to detect. Here, we employ live-cell interf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b86be0bc449515a47b1f717cec70f9
https://pubmed.ncbi.nlm.nih.gov/19206480
https://pubmed.ncbi.nlm.nih.gov/19206480
Autor:
Joanna Schmit, James K. Gimzewski, Michael A. Teitell, Matthew J. Frank, Sen Han, Joshua J. Troke, Jason Reed
Publikováno v:
Digital Holography and Three-Dimensional Imaging.
We demonstrate the mechanical probing of tens of cells simultaneously while an interferometric optical profiler measures both the force of the probes and the response of the cells with nanometer accuracy over a wide field.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a80c3861a4d6b62e32deb71c3eea29ae
https://doi.org/10.1364/dh.2008.dmb3
https://doi.org/10.1364/dh.2008.dmb3
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 8:401-410
Strategies for the use of 1H and 19F nuclear magnetic resonance (NMR) spectroscopy as an aid to the study of the metabolic fate of fluorinated drugs are discussed with reference to the application of these methods to flurbiprofen metabolism in man. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6edbad592deacad889b2fd5beb6043d2
https://doi.org/10.1016/0731-7085(90)80067-y
https://doi.org/10.1016/0731-7085(90)80067-y
Autor:
Christoph Plass, Jason S. Hong, Dorina Gui, Yue-Zhong Wu, Michael A. Teitell, York Marahrens, Moira Regelson, Samuel W. French, Rhine R. Shen, Shih-Shih Chen, Herbert C. Morse, David W. Dawson, J. Said, Joshua J. Troke
Publikováno v:
Oncogene. 26(29)
Most human lymphomas originate from transformed germinal center (GC) B lymphocytes. While activating mutations and translocations of MYC, BCL2 and BCL6 promote specific GC lymphoma subtypes, other genetic and epigenetic modifications that contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1fab0ffd2e0ed4382fa889f2983f01
https://pubmed.ncbi.nlm.nih.gov/17260020
https://pubmed.ncbi.nlm.nih.gov/17260020
Autor:
Jason G. Weinger, Katrina K. Hoyer, Joshua J. Troke, Michael A. Teitell, Christian Raphalides, Jun Xu, Mark W. Sleeman, Irwin J. Kurland, Mathilde Renard, W.N. Paul Lee, Mohammed F. Saad, Bhavapriya Vaitheesyaran, Lori C. Gowen
Publikováno v:
Diabetes. 55(12)
Despite altered regulation of insulin signaling, Pten(+/-) heterodeficient standard diet-fed mice, approximately 4 months old, exhibit normal fasting glucose and insulin levels. We report here a stable isotope flux phenotyping study of this "silent"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82091f6e91c253add559280f77210456
https://pubmed.ncbi.nlm.nih.gov/17130482
https://pubmed.ncbi.nlm.nih.gov/17130482
Autor:
Carla M. Koehler, Robert N. Rainey, Heidi M. McBride, Joshua J. Troke, Samuel W. French, Hsiao-Wen Chen, David W. Dawson, Jason S. Hong, Cynthia E. Balatoni, Michael A. Teitell, Sylwia Wasiak
Publikováno v:
Molecular and cellular biology. 26(22)
We recently identified polynucleotide phosphorylase (PNPase) as a potential binding partner for the TCL1 oncoprotein. Mammalian PNPase exhibits exoribonuclease and poly(A) polymerase activities, and PNPase overexpression inhibits cell growth, induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e211465a1b9a5153e7563674a3a32d27
https://pubmed.ncbi.nlm.nih.gov/16966381
https://pubmed.ncbi.nlm.nih.gov/16966381