Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J. Trittmacher"'
Publikováno v:
ChemInform. 33
Publikováno v:
Die Pharmazie. 60(8)
The o-nitrobenzylidene acetoacetic esters 1 dimerize in the presence of BuLi or LDA to give the cyclohexenes 2 in poor yield. Two diastereomer of 2b were isolated, whose configuration is deduced by nmr-spectroscopic methods.
Publikováno v:
Die Pharmazie. 60(7)
The reaction of the 1,5-diketones 1 with acetic anhydride/acetic acid in the presence of zinc chloride yields the 4-aryl-4H-pyrans 2 as main products. The annulated lactone 3 and the cyclohexene derivatives 5 are isolated as by-products. The configur
Publikováno v:
ChemInform. 35
Publikováno v:
Die Pharmazie. 58(11)
Hydrolysis of the dienamine function of the dihydrobiphenyls 3 leads to a mixture of the tautomers 4A-C (NMR). The structures of the starting material 3a and the products 4cA and 4bC are confirmed by X-ray crystal analysis. The biphenyls 5 are formed
Publikováno v:
ChemInform. 34
Publikováno v:
Die Pharmazie. 58(8)
Pyrano[3,4-c]quinolines from 1-desaza-1-oxa-nifedipine The reaction of the 1,5-diketone 1 with acetic anhydride/acetic acid in the presence of zinc chloride yields the 1-desaza-1-oxa-nifedipine 2 and the annulated lactone 3 as a by-product. The struc
Publikováno v:
ChemInform. 34
Publikováno v:
Die Pharmazie. 57(9)
The bistetronic derivatives 4, obtained by base catalyzed reaction of the aldehydes 3 with surplus tetronic acid (2), cyclize in polyphosphoric acid (PPA) to yield the 4H-pyranes 5. The amino derivative 6 formed by reduction of the nitro group of 5a
Publikováno v:
Die Pharmazie. 57(8)
Eight new 4-aryl-2,6-dimethyl-4H-pyrane-3,5-dicarboxylic acid esters 2 and a new 2-amino-2-nor derivative 7 are synthesized using known methods, whose limitations are shown. In contrast to the isoelectronic 4-aryl-1,4-dihydro-pyridines (DHP) 1 the co