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Akademický článek
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Autor:
J. Toftegaard, Oscar Casares-Magaz, Ludvig Paul Muren, A.G. Andersen, Lise Bentzen, S. Thörnqvist, Jørgen B. B. Petersen
Publikováno v:
Gravgaard Andersen, A, Casares-Magaz, O, Petersen, J, Toftegaard, J, Bentzen, L, Thörnqvist, S & Muren, L P 2017, ' Beam angle evaluation to improve inter-fraction motion robustness in pelvic lymph node irradiation with proton therapy ', Acta Oncologica, vol. 56, no. 6, pp. 846-852 . https://doi.org/10.1080/0284186X.2017.1317108
BACKGROUND:Proton therapy dose distributions are sensitive to range variations, e.g. arising from inter-fraction organ motion. The aim of this study was to evaluate the inter-fraction motion robustness of proton beams from different beam angles in ir
Publikováno v:
Toftegaard, J, Hansen, R, Ravkilde, T, Macek, K & Poulsen, P R 2017, ' An experimentally validated couch and MLC tracking simulator used to investigate hybrid couch-MLC tracking ', Medical Physics, vol. 44, no. 3, pp. 798-809 . https://doi.org/10.1002/mp.12104
PURPOSE/OBJECTIVE: Couch and MLC tracking are two novel techniques to mitigate intrafractional tumor motion on a conventional linear accelerator, but both techniques still have residual dosimetric errors. Here, we first propose and experimentally val
Autor:
J. Toftegaard, T. Ravkilde, Cai Grau, Esben S. Worm, Per Rugaard Poulsen, Kristijan Macek, Rune Hansen
Publikováno v:
Medical Physics. 43:2387-2398
Purpose: Couch and MLC tracking are two promising methods for real-time motion compensation during radiation therapy. So far, couch and MLC tracking experiments have mainly been performed by different research groups, and no direct comparison of couc
Autor:
Morten Høyer, Rune Hansen, Britta Weber, H. Wan, Parag J. Parikh, Per Rugaard Poulsen, Jenny Bertholet, J. Toftegaard, Esben S. Worm
Publikováno v:
Bertholet, J, Toftegaard, J, Hansen, R, Worm, E S, Wan, H, Parikh, P J, Weber, B, Hoyer, M & Poulsen, P R 2018, ' Automatic online and real-time tumour motion monitoring during stereotactic liver treatments on a conventional linac by combined optical and sparse monoscopic imaging with kilovoltage x-rays (COSMIK) ', Physics in Medicine and Biology, vol. 63, no. 5, 055012 . https://doi.org/10.1088/1361-6560/aaae8b
The purpose of this study was to develop, validate and clinically demonstrate fully automatic tumour motion monitoring on a conventional linear accelerator by combined optical and sparse monoscopic imaging with kilovoltage x-rays (COSMIK). COSMIK com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335ad5acaec7a71f1d37d42d906503f0
https://pure.au.dk/portal/da/publications/automatic-online-and-realtime-tumour-motion-monitoring-during-stereotactic-liver-treatments-on-a-conventional-linac-by-combined-optical-and-sparse-monoscopic-imaging-with-kilovoltage-xrays-cosmik(c791605e-8f34-4d3b-868f-d39905ffbb0d).html
https://pure.au.dk/portal/da/publications/automatic-online-and-realtime-tumour-motion-monitoring-during-stereotactic-liver-treatments-on-a-conventional-linac-by-combined-optical-and-sparse-monoscopic-imaging-with-kilovoltage-xrays-cosmik(c791605e-8f34-4d3b-868f-d39905ffbb0d).html
Autor:
Dan Ruan, Ricky O'Brien, Floris Ernst, Per Rugaard Poulsen, Kei Ichiji, Noriyasu Homma, Paul J. Keall, J. Toftegaard
Publikováno v:
Toftegaard, J, Keall, P J, O'Brien, R, Ruan, D, Ernst, F, Homma, N, Ichiji, K & Poulsen, P R 2018, ' Potential improvements of lung and prostate MLC tracking investigated by treatment simulations ', Medical Physics, vol. 45, no. 5, pp. 2218-2229 . https://doi.org/10.1002/mp.12868
PURPOSE/OBJECTIVES: Intrafraction tumor motion during external radiotherapy is a challenge for the treatment accuracy. A novel technique to mitigate the impact of tumor motion is real-time adaptation of the multileaf collimator (MLC) aperture to the
Autor:
Parag J. Parikh, J. Toftegaard, Jenny Bertholet, F Chotard, M.L. Schmidt, Per Rugaard Poulsen, H. Wan
Publikováno v:
Bertholet, J, Wan, H, Toftegaard, J, Schmidt, M L, Chotard, F, Parikh, P J & Poulsen, P R 2017, ' Fully automatic segmentation of arbitrarily shaped fiducial markers in cone-beam CT projections. ', Physics in Medicine and Biology, vol. 62, no. 4, pp. 1327-1341 . https://doi.org/10.1088/1361-6560/aa52f7
Radio-opaque fiducial markers of different shapes are often implanted in or near abdominal or thoracic tumors to act as surrogates for the tumor position during radiotherapy. They can be used for real-time treatment adaptation, but this requires a ro
Autor:
Rune Hansen, Morten Høyer, Jenny Bertholet, Britta Weber, Parag J. Parikh, Per Rugaard Poulsen, H. Wan, J. Toftegaard, Esben S. Worm
Publikováno v:
Radiotherapy and Oncology. 127:S335-S336
Autor:
Oliver Jäkel, Armin Lühr, Niels Bassler, Jørgen B. B. Petersen, Lise Saksø Mortensen, Michael R. Kramer, J. Toftegaard, Emanuele Scifoni, Jens Overgaard, Brita Singers Sørensen
Publikováno v:
Bassler, N, Toftegaard, J, Lühr, A, Sørensen, B S, Scifoni, E, Krämer, M, Jäkel, O, Mortensen, L S, Overgaard, J & Petersen, J B 2014, ' LET-painting increases tumour control probability in hypoxic tumours ', Acta Oncologica, vol. 53, no. 1, pp. 25-32 . https://doi.org/10.3109/0284186X.2013.832835
LET-painting was suggested as a method to overcome tumour hypoxia. In vitro experiments have demonstrated a well-established relationship between the oxygen enhancement ratio (OER) and linear energy transfer (LET), where OER approaches unity for high