Zobrazeno 1 - 10
of 253
pro vyhledávání: '"J. Titchener"'
Autor:
Matthew Lakelin, Suzanne S. Farid, Maria M. Papathanasiou, Christos Stamatis, Nigel J. Titchener-Hooker, Nilay Shah
Publikováno v:
Cancer Gene Therapy. 27:799-809
Chimeric antigen receptor (CAR) T cells are considered a potentially disruptive cancer therapy, showing highly promising results. Their recent success and regulatory approval (both in the USA and Europe) are likely to generate a rapidly increasing de
The Bibliotheca Teubneriana, established in 1849, has evolved into the world's most venerable and extensive series of editions of Greek and Latin literature, ranging from classical to Neo-Latin texts. Some 4-5 new editions are published every year. A
Autor:
Nigel J. Titchener-Hooker, Stephen Goldrick, Christos Stamatis, Richard Turner, Suzanne S. Farid, David Gruber
Publikováno v:
Journal of Chromatography A. 1596:104-116
Chromatography remains the workhorse in antibody purification; however process development and characterisation still require significant resources. The high number of operating parameters involved requires extensive experimentation, traditionally pe
Autor:
Ajoy Velayudhan, David J. Roush, Spyridon Konstantinidis, Nigel J. Titchener-Hooker, John P. Welsh
Publikováno v:
Biotechnology Progress
Recently, a grid compatible Simplex variant has been demonstrated to identify optima consistently and rapidly in challenging high throughput (HT) applications in early bioprocess development. Here, this method is extended by deploying it to multi-obj
Publikováno v:
Research in Social and Administrative Pharmacy. 14:86-95
Background There are hidden drug administration costs that arise from a mismatch between end-user preferences and how manufacturers choose to formulate their drug products for delivery to patients. The corollary of this is: there are “intangible be
Publikováno v:
Biotechnology Journal
Increases in mammalian cell culture titres and densities have placed significant demands on primary recovery operation performance. This article presents a methodology which aims to screen rapidly and evaluate primary recovery technologies for their
Autor:
Marco Rito-Palomares, Mario A. Torres-Acosta, José M. Aguilar-Yáñez, Jorge F. B. Pereira, Nigel J. Titchener-Hooker, Mara G. Freire, João A. P. Coutinho
Publikováno v:
Separation and purification technology
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2018-11-26T16:03:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-12 CONACYT CICECO-Aveiro Institute of Materials - national funds through the FCT/MEC FEDER under the PT2020 Partnership Agreement European Resea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0aaa54e9b7cb5fad1704b9d71eebcb0
http://hdl.handle.net/10773/37056
http://hdl.handle.net/10773/37056
Autor:
Ranga Godavarti, Jonida Basha, Daniel LaCasse, Tarit Mukhopadhyay, John M. Frostad, Doug Millard, Aaron Noyes, Benjamin Huffman, Richard S. Wright, Nigel J. Titchener-Hooker, Jim Mullin, Khurram Sunasara, Robert Fahrner, Scott Cook
Publikováno v:
Journal of Membrane Science. 496:199-210
Depth filtration is employed in the production of many biological products. Although high throughput process development is available for most purification operations, options for high throughput depth filtration are limited. In this report, we descr
Autor:
Marco Rito-Palomares, José M. Aguilar-Yáñez, Mario A. Torres-Acosta, Nigel J. Titchener-Hooker
Publikováno v:
Biotechnology Progress
Uricase is the enzyme responsible for the breakdown of uric acid, the key molecule leading to gout in humans, into allantoin, but it is absent in humans. It has been produced as a PEGylated pharmaceutical where the purification is performed through t
Autor:
Khurram Sunasara, Aaron Noyes, Nick Merchant, Nigel J. Titchener-Hooker, Ben Huffman, Ranga Godavarti, Jonathan Coffman, Tarit Mukhopadhyay, Alex Berrill
Publikováno v:
Biotechnology and Bioengineering. 112:1568-1582
Multivalent polysaccharide conjugate vaccines are typically comprised of several different polysaccharides produced with distinct and complex production processes. Particle conditioning steps, such as precipitation and flocculation, may be used to ai