Zobrazeno 1 - 10
of 36
pro vyhledávání: '"J. Tiago Gonçalves"'
Autor:
M. Agustina Frechou, Sunaina S. Martin, Kelsey D. McDermott, Evan A. Huaman, Şölen Gökhan, Wolfgang A. Tomé, Ruben Coen-Cagli, J. Tiago Gonçalves
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Adult neurogenesis is a unique form of neuronal plasticity in which newly generated neurons are integrated into the adult dentate gyrus in a process that is modulated by environmental stimuli. Adult-born neurons can contribute to spatial mem
Externí odkaz:
https://doaj.org/article/74f229e468134b87b7d41be831a1df1b
Autor:
Joanna Krzyspiak, Jingqi Yan, Hiyaa S. Ghosh, Basia Galinski, Pablo J. Lituma, Karina Alvina, Alexandra Quezada, Samantha Kee, Marta Grońska-Pęski, Yi De Tai, Kelsey McDermott, J. Tiago Gonçalves, R. Suzanne Zukin, Daniel A. Weiser, Pablo E. Castillo, Kamran Khodakhah, Jean M. Hébert
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102700- (2022)
Externí odkaz:
https://doaj.org/article/68a515075124457184aa08612322ab77
Autor:
Joanna Krzyspiak, Jingqi Yan, Hiyaa S. Ghosh, Basia Galinski, Pablo J. Lituma, Karina Alvina, Alexandra Quezada, Samantha Kee, Marta Grońska-Pęski, Yi De Tai, Kelsey McDermott, J. Tiago Gonçalves, R. Suzanne Zukin, Daniel A. Weiser, Pablo E. Castillo, Kamran Khodakhah, Jean M. Hébert
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102642- (2022)
Neural precursor cells (NPCs) transplanted into the adult neocortex generate neurons that synaptically integrate with host neurons, supporting the possibility of achieving functional tissue repair. However, poor survival and functional neuronal recov
Externí odkaz:
https://doaj.org/article/e8b40cf4b82b434db9390a7e7aa82458
Autor:
Jake T. Jordan, Kelsey D. McDermott, M. Agustina Frechou, Matthew Shtrahman, J. Tiago Gonçalves
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100770- (2021)
Summary: Several mouse in vivo neuronal recording techniques require head fixation. Head-fixed treadmill walking can be used to design tasks that enable the study of neural activity in the context of behavior. Here, we provide a detailed protocol for
Externí odkaz:
https://doaj.org/article/348e5aa7ed7e40f9a7b573f84653ff07
Autor:
Nannan Guo, Kelsey D McDermott, Yu-Tzu Shih, Haley Zanga, Debolina Ghosh, Charlotte Herber, William R Meara, James Coleman, Alexia Zagouras, Lai Ping Wong, Ruslan Sadreyev, J Tiago Gonçalves, Amar Sahay
Publikováno v:
eLife, Vol 11 (2022)
Experience governs neurogenesis from radial-glial neural stem cells (RGLs) in the adult hippocampus to support memory. Transcription factors (TFs) in RGLs integrate physiological signals to dictate self-renewal division mode. Whereas asymmetric RGL d
Externí odkaz:
https://doaj.org/article/0e24b10980c34ec5a18e2dfb551081df
Autor:
Stephen Johnston, Sarah L Parylak, Stacy Kim, Nolan Mac, Christina Lim, Iryna Gallina, Cooper Bloyd, Alexander Newberry, Christian D Saavedra, Ondrej Novak, J Tiago Gonçalves, Fred H Gage, Matthew Shtrahman
Publikováno v:
eLife, Vol 10 (2021)
Recombinant adeno-associated virus (rAAV) has been widely used as a viral vector across mammalian biology and has been shown to be safe and effective in human gene therapy. We demonstrate that neural progenitor cells (NPCs) and immature dentate granu
Externí odkaz:
https://doaj.org/article/d6ed94cb81614f08ad343b6ed27bc2a8
Autor:
Kelsey D. McDermott, M. Agustina Frechou, Jake T. Jordan, Sunaina S. Martin, J. Tiago Gonçalves
Publikováno v:
bioRxiv
Aging is associated with cognitive deficits, with spatial memory being very susceptible to decline. The hippocampal dentate gyrus (DG) is important for processing spatial information in the brain and is particularly vulnerable to aging, yet its spars
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000e865184808c3b3c4f76a584143458
https://doi.org/10.1101/2023.03.03.531021
https://doi.org/10.1101/2023.03.03.531021
Autor:
M. Agustina Frechou, Sunaina S. Martin, Kelsey D. McDermott, Şölen Gökhan, Wolfgang A. Tomé, Ruben Coen-Cagli, J. Tiago Gonçalves
Adult neurogenesis is a unique form of neuronal plasticity in which newly generated neurons are integrated into the adult dentate gyrus in a process that is modulated by environmental stimuli. Adult-born neurons can contribute to spatial memory but i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2052cd7ab7b590f3f46426dcaf932d1
https://doi.org/10.1101/2022.11.30.518622
https://doi.org/10.1101/2022.11.30.518622
Publikováno v:
eLife, Vol 6 (2017)
A leading theory holds that neurodevelopmental brain disorders arise from imbalances in excitatory and inhibitory (E/I) brain circuitry. However, it is unclear whether this one-dimensional model is rich enough to capture the multiple neural circuit a
Externí odkaz:
https://doaj.org/article/43f3ac1210e8404a89a511998e25af56
Autor:
Kaoutsar Nasrallah, M. Agustina Frechou, Young J. Yoon, Subrina Persaud, J. Tiago Gonçalves, Pablo E. Castillo
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Epilepsy is a devastating brain disorder for which effective treatments are very limited. There is growing interest in early intervention, which requires a better mechanistic understanding of the early stages of this disorder. While diverse brain ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4e08024e6039a587769fc2a76ab4a4
https://doi.org/10.1073/pnas.2201151119
https://doi.org/10.1073/pnas.2201151119