Zobrazeno 1 - 6
of 6
pro vyhledávání: '"J. Thom Deahl"'
Autor:
Joel P. Bercu, Robert B. L. Van Lier, Stuart Morton, J. Thom Deahl, Vijay K. Gombar, Courtney M. Callis
Publikováno v:
Regulatory Toxicology and Pharmacology. 57:300-306
The current risk assessment approach for addressing the safety of very small concentrations of genotoxic impurities (GTIs) in drug substances is the threshold of toxicological concern (TTC). The TTC is based on several conservative assumptions becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e22a98073853d371e6a68c0371c9a3
https://doi.org/10.1016/j.yrtph.2010.03.010
https://doi.org/10.1016/j.yrtph.2010.03.010
Autor:
Ronald K. Newton, Mohammed Islaih, Baohui Li, Julie L. Altizer, Jaclyn L. Reid-Hubbard, David E. Watson, Ibrahim Kadura, J. Thom Deahl
Publikováno v:
Environmental and Molecular Mutagenesis. 44:401-419
Exposure to DNA-damaging agents can elicit a variety of stress-related responses that may alter the gene expression of numerous biological pathways. We used Affymetrix microarrays to detect gene expression changes in mouse lymphoma (L5178Y) and human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31206786aa78a52f909a83cfe0863cbe
https://doi.org/10.1002/em.20065
https://doi.org/10.1002/em.20065
Variation in Photodynamic Efficacy during the Cellular Uptake of Two Phthalocyanine Photosensitizers
Publikováno v:
Photochemistry and Photobiology. 67:720-728
A decrease in the efficacy of photodynamic therapy (PDT) with phthalocyanine photosensitizers was observed for lymphoblastic murine and human cell lines as the time between the addition of the photosensitizer, aluminum phthalocyanine (AIPc), to the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c799e201f2fdce33c2f2a4070bc605
https://doi.org/10.1111/j.1751-1097.1998.tb09477.x
https://doi.org/10.1111/j.1751-1097.1998.tb09477.x
Publikováno v:
Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2bf06ad1af6579593528320e96a613
https://doi.org/10.1002/9780470145890.ch7
https://doi.org/10.1002/9780470145890.ch7
Autor:
Mohammed Islaih, Baohui Li, Ibrahim A. Kadura, Jaclyn L. Reid‐Hubbard, J. Thom Deahl, Julie L. Altizer, David E. Watson, Ronald K. Newton
Publikováno v:
Environmental & Molecular Mutagenesis; Nov2004, Vol. 44 Issue 5, p401-419, 19p
Autor:
Islaih M; Investigative Toxicology, Toxicology and Drug Disposition, A Division of Eli Lilly and Company, P.O. Box 708, Greenfield, IN 46140, USA., Halstead BW, Kadura IA, Li B, Reid-Hubbard JL, Flick L, Altizer JL, Thom Deahl J, Monteith DK, Newton RK, Watson DE
Publikováno v:
Mutation research [Mutat Res] 2005 Oct 15; Vol. 578 (1-2), pp. 100-16.