Zobrazeno 1 - 10
of 230
pro vyhledávání: '"J. Tew"'
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102658- (2023)
8-oxoA, a major oxidation product of adenosine, is a mispairing, mutagenic lesion that arises in DNA and RNA when •OH radicals or one-electron oxidants attack the C8 adenine atom or polymerases misincorporate 8-oxo(d)ATP. The danger of 8-oxoA is un
Externí odkaz:
https://doaj.org/article/5af356c9a0a24792b2236ee8a98f7221
Autor:
Kaylee M. Wilburn, Julianna B. Blaylock, Kerry C. Metcalfe, Brian Y. Hsueh, Daniel J. Tew, Christopher M. Waters
Publikováno v:
Israel Journal of Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1215a713c52674f3abf449e09c7f2b16
https://doi.org/10.1002/ijch.202200084
https://doi.org/10.1002/ijch.202200084
Akademický článek
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Autor:
J.J.A. Baldonado, A. Aboukheir, E.I.Q. Villanueva, T. Draeger, J. Tew, J. Garrett, C. Moodie, J.P. Fontaine, E.M. Toloza
Publikováno v:
Journal of Thoracic Oncology. 17:S221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a4efcbcd5016d396bb6c77a4c69e90f
https://doi.org/10.1016/j.jtho.2022.07.368
https://doi.org/10.1016/j.jtho.2022.07.368
Autor:
Tong-Lay Lau, John D. Wade, Timothy Johanssen, Cyril C. Curtain, Varsha Lal, Kevin J. Barnham, Jeffrey P. Smith, Roberto Cappai, Giuseppe D. Ciccotosto, Colin L. Masters, Deborah J. Tew, Danielle G. Smith, Keyla Perez, Frances Separovic, Simon C. Drew
Publikováno v:
Neurobiology of Aging. 32:235-248
Previous studies suggest membrane binding is a key determinant of amyloid β (Aβ) neurotoxicity. However, it is unclear whether this interaction is receptor driven. To address this issue, a D-handed enantiomer of Aβ42 (D-Aβ42) was synthesized and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507e07d4491df8bf24a4c7869bf1575d
https://doi.org/10.1016/j.neurobiolaging.2009.02.018
https://doi.org/10.1016/j.neurobiolaging.2009.02.018
Autor:
Andrew F. Hill, Deborah J. Tew, Frances Separovic, Martin Boland, Kevin J. Barnham, Steven J. Collins, Cathryn L. Haigh, Michael James, Claire R. Hatty, Colin L. Masters
Publikováno v:
Journal of Biological Chemistry. 285:32282-32292
Although the N terminus of the prion protein (PrP(C)) has been shown to directly associate with lipid membranes, the precise determinants, biophysical basis, and functional implications of such binding, particularly in relation to endogenously occurr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d575fed04eef7f81d5c4bd4b8d195904
https://doi.org/10.1074/jbc.m110.123398
https://doi.org/10.1074/jbc.m110.123398
Autor:
Victoria M. Perreau, Anthony R. White, Shayne A. Bellingham, Su San Mok, Henning Hermjakob, Sandra Orchard, Tiffany F. Cowie, Noel G. Faux, James A. Duce, Peter J. Crouch, Ya Hui Hung, Simon James, Qiao-Xin Li, Colin L. Masters, Roberto Cappai, Giuseppe D. Ciccotosto, Ashley I. Bush, Andrew F. Hill, Deborah J. Tew, Genevieve Evin, Paul A. Adlard
Publikováno v:
PROTEOMICS. 10:2377-2395
The primary constituent of the amyloid plaque, beta-amyloid (Abeta), is thought to be the causal "toxic moiety" of Alzheimer's disease. However, despite much work focused on both Abeta and its parent protein, amyloid precursor protein (APP), the func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813048f6ba1560537eb43470088f2367
https://doi.org/10.1002/pmic.200900773
https://doi.org/10.1002/pmic.200900773
Autor:
Roberto Cappai, Kevin J. Barnham, Cyril C. Curtain, Keyla Perez, Colin L. Masters, Deborah J. Tew, Giuseppe D. Ciccotosto, Danielle G. Smith, John F. Boas
Publikováno v:
Journal of Alzheimer's Disease. 19:1387-1400
Amyloid-beta peptide (Abeta) toxicity is thought to be responsible for the neurodegeneration associated with Alzheimer's disease. While the mechanism(s) that modulate this toxicity are still widely debated, it has previously been demonstrated that mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587dfefdb88ae116b760f74fb77211a5
https://doi.org/10.3233/jad-2010-1334
https://doi.org/10.3233/jad-2010-1334
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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