Zobrazeno 1 - 10
of 957
pro vyhledávání: '"J. Tepper"'
Publikováno v:
Cephalalgia Reports, Vol 7 (2024)
Background Here, we review studies conducted in the last 25 years that attempted to increase our understanding of the various receptors that play a role in the pathogenesis and treatment of migraine. Several of these studies evaluated the effects of
Externí odkaz:
https://doaj.org/article/0c173e779d174164a9a62756aed7df63
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background New guidelines for cluster headache clinical trials were recently published. We welcome these new guidelines and raise additional considerations in trial methodologies. Main body We present non-inferiority trials to overcome ethic
Externí odkaz:
https://doaj.org/article/25b7b6e7cf914730b04522bd51b1ac22
Autor:
Ani C. Khodavirdi, Jasjit K. Multani, Sam S. Oh, Fiston Vuvu, Mark E. Bensink, Karen M. Stockl, Kevin Hawkins, Chia-Chun Chiang, A. Laine Green, Stewart J. Tepper
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionMigraine is a debilitating neurological disorder, with a wide range of symptoms and disease burden, underscoring the heterogeneity of patients’ disease characteristics and treatment needs. To characterize the profile of migraine patient
Externí odkaz:
https://doaj.org/article/40ba0f75cd51477882b9369731b68aae
Autor:
Patricia Pozo-Rosich, Messoud Ashina, Stewart J. Tepper, Sidsel Jensen, Line Pickering Boserup, Mette Krog Josiassen, Bjørn Sperling
Publikováno v:
Neurology and Therapy, Vol 13, Iss 2, Pp 339-353 (2024)
Abstract Introduction In the DELIVER study, eptinezumab reduced monthly migraine days (MMDs) more than placebo in patients with 2–4 prior preventive migraine treatment failures. This post hoc analysis evaluated the efficacy of eptinezumab across th
Externí odkaz:
https://doaj.org/article/db3613d3bbe843fc9dda99c7098d8dd2
Autor:
Messoud Ashina, Stewart J. Tepper, Astrid Gendolla, Bjørn Sperling, Anders Ettrup, Mette Krog Josiassen, Amaal J. Starling
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Eptinezumab demonstrated efficacy in adults with migraine and prior preventive treatment failures in the placebo-controlled phase of the DELIVER clinical trial; its long-term effectiveness in this population has not yet been repor
Externí odkaz:
https://doaj.org/article/b734ea6886ea41c5ad098af8bbd3e973
Autor:
Andrew M. Blumenfeld, Richard B. Lipton, Stephen Silberstein, Stewart J. Tepper, Larry Charleston, Stephen Landy, Deena E. Kuruvilla, Aubrey Manack Adams
Publikováno v:
Neurology and Therapy, Vol 12, Iss 5, Pp 1533-1551 (2023)
Abstract Migraine is a neurologic disease with a complex pathophysiology that can be controlled with current treatment options but not cured. Therefore, treatment expectations are highly variable. The concept of migraine freedom was recently introduc
Externí odkaz:
https://doaj.org/article/bb3f6e1700ef433e92ce463429385b39
Autor:
Lara J. Brindisi, Weiting Lyu, H. Rodolfo Juliani, Qingli Wu, Beverly J. Tepper, James E. Simon
Publikováno v:
Food Chemistry Advances, Vol 3, Iss , Pp 100389- (2023)
Brassica vegetables (Brassicaceae) produce a unique class of compounds known as glucosinolates. The breakdown products of glucosinolates, including isothiocyanates, are recognized as the primary sources of bioactivity and characteristic taste, flavor
Externí odkaz:
https://doaj.org/article/920b5affe46a47458eb66e6277923e2f
Autor:
Stewart J. Tepper, Jessica Cirillo, Edward Kim, Gil L’Italien, Julie M. Tweedie, Kunal Lodaya, Dushon Riley, Farah Pathan, Nicholas Antaki, Brian H. Nathanson, Peter McAllister
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background Migraine affects 1.1 billion people globally and is the second leading cause of disability worldwide. In clinical trials, treatment efficacy is evaluated by comparing the differential responses in the treatment and placebo arms. A
Externí odkaz:
https://doaj.org/article/3e58907b2f604a08a99a67903cab2933
Autor:
Andrew Blumenfeld, Stewart J. Tepper, Rashna Khanna, Erin Doty, Maurice Vincent, Sheila I. Miller
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundSerotonin syndrome (SS) symptoms overlap with adverse events associated with lasmiditan, a 5-HT (serotonin)1F receptor agonist for acute treatment of migraine. Because SS symptoms are heterogeneous, diagnosis can be challenging, and potenti
Externí odkaz:
https://doaj.org/article/2ab0e1be355a4f1794f69c565aa6259e
Autor:
Stewart J. Tepper, Jessica Ailani, Sutapa Ray, Joe Hirman, Stephen B. Shrewsbury, Sheena K. Aurora
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Headache recurrence is a common feature of acute therapies, whether approved or still in development, and continues to be a significant problem for both the patient and the clinician. Further complicating this issue is lack of sta
Externí odkaz:
https://doaj.org/article/2856343935984219ba57100a44c2299d