Zobrazeno 1 - 10
of 57
pro vyhledávání: '"J. T. Tildon"'
Publikováno v:
Neurochemical Research. 22:1159-1164
Leucine and α-ketoisocaproate (α-KIC) were perfused at increasing concentrations into rat brain hippocampus by microdialysis to mimic the conditions of maple syrup urine disease. The effects of elevated leucine or α-KIC on the oxidation of L-[U-14
Publikováno v:
Pediatric Research. 40:135-141
Glucose has been thought to be the primary substrate for energy metabolism in the developing lung; however, alternate substrates are used for energy metabolism in other organs. To examine the role of alternate substrates in the lung, we measured rate
Publikováno v:
Developmental Neuroscience. 18:420-425
alpha-Ketoisocaproate was infused into the brain of free-moving, awake rats by microdialysis to create a microenvironment similar to that found in maple syrup urine disease. The eluate of the probe was analyzed for amino acids to determine if alpha-k
Publikováno v:
Neurochemical Research. 20:1491-1501
Malate has a number of key roles in the brain, including its function as a tricarboxylic acid (TCA) cycle intermediate, and as a participant in the malate-aspartate shuttle. In addition, malate is converted to pyruvate and CO2 via malic enzyme and ma
Publikováno v:
Molecular and Chemical Neuropathology. 19:219-233
The effect of aluminum on the metabolism of glutamate and glutamine in astrocytes was studied to provide information about a possible biochemical mechanism for aluminum neurotoxicity and its potential contribution to neurodegenerative disease. Exposu
Publikováno v:
Developmental Neuroscience. 15:226-332
This report extends the finding that serum protein(s) (0.5 mg/ml) caused a 50% decrease in the rate of glucose oxidation by dissociated brain cells with only marginal effects on the oxidation of other substrates. Since dissociated cells represent a h
Publikováno v:
Neurochemical Research. 15:1115-1122
Glutamine synthetase (GS) activity in cultured rat astrocytes was measured in extracts and compared to the intracellular rate of glutamine synthesis by intact control astrocytes or astrocytes exposed to 1 mM 8-bromo-cAMP (8Br-cAMP) + 1 microM dexamet
Publikováno v:
Developmental neuroscience. 20(4-5)
Since lactate released by glial cells may be a key substrate for energy in neurons, the kinetics for the uptake of L-[U-14C]lactate by cortical synaptic terminals from 7- to 8-week-old rat brain were determined. Lactate uptake was temperature-depende
Publikováno v:
Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians. 9(1)
We report three children with autistic spectrum disorders who underwent upper gastrointestinal endoscopy and intravenous administration of secretin to stimulate pancreaticobiliary secretion. All three had an increased pancreaticobiliary secretory res
Publikováno v:
Neurochemical research. 22(9)
Leucine and alpha-ketoisocaproate (alpha-KIC) were perfused at increasing concentrations into rat brain hippocampus by microdialysis to mimic the conditions of maple syrup urine disease. The effects of elevated leucine or alpha-KIC on the oxidation o