Zobrazeno 1 - 4
of 4
pro vyhledávání: '"J. T. Strupczewski"'
Autor:
Hugo M. Vargas, J. T. Strupczewski, L. Griffiths, R. Corbett, J. E. Shipley, S. Kongsamut, A. M. Szczepanik, U. Shukla, D. J. Turk, M. R. Szewczak
Publikováno v:
CNS Drug Reviews. 3:120-147
Schizophrenia is a severe mental illness affecting an estimated 1% of the world's population (73). The disease has an uncertain pathophysiology possibly leading to disruption of dopaminergic neural systems through poorly understood interactions of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94daa66c5e3c644f4af0a5e26b51153a
https://doi.org/10.1111/j.1527-3458.1997.tb00320.x
https://doi.org/10.1111/j.1527-3458.1997.tb00320.x
Autor:
M R, Szewczak, R, Corbett, D K, Rush, C A, Wilmot, P G, Conway, J T, Strupczewski, M, Cornfeldt
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(3)
Iloperidone (1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone) demonstrated a potent antipsychotic profile in several in vitro and in vivo animal models. Iloperidone displaced ligand binding at D2 dopamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86089b5f7148e7f040e6b8ce2e1abcf6
https://pubmed.ncbi.nlm.nih.gov/7562515
https://pubmed.ncbi.nlm.nih.gov/7562515
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(9)
Iloperidone, 1(-)[4(-)[3(-)[4-(6-fluro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone, is currently undergoing clinical trials as a potential antipsychotic agent. Iloperidone was found to be extensively metabolized to a numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61b3ba8d7b1a9f28bc8c8bfaf9d307bf
https://pubmed.ncbi.nlm.nih.gov/8565786
https://pubmed.ncbi.nlm.nih.gov/8565786
Autor:
A. Giovanni, P. Sokoloff, S. Kongsamut, J. T. Strupczewski, K. Bordeau, D. DeSteno, M. Kenney, B. Harris, S. Kafka, J. Hendrix, J.M. Gries, A.M. Szczepanik, S. Dwyer
Publikováno v:
Schizophrenia Research. 60:312
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de32f6ead7314ad2304eb761661a49a4
https://doi.org/10.1016/s0920-9964(03)80254-2
https://doi.org/10.1016/s0920-9964(03)80254-2