Zobrazeno 1 - 10
of 36
pro vyhledávání: '"J. T. Ransom"'
Publikováno v:
Environmental Research Letters, Vol 11, Iss 9, p 094019 (2016)
The Deepwater Horizon oil spill (DWHOS) spatially and temporally overlapped with the spawning of many fish species, including Red Snapper, one of the most economically important reef fish in the Gulf of Mexico. To investigate potential impacts of the
Externí odkaz:
https://doaj.org/article/402f7a6a9fb74b7c9cef4798d4afb288
Publikováno v:
B-Lymphocyte Differentiation ISBN: 9781351070010
The ability of the B cell to distinguish among regulatory species is probably determined at multiple levels. These include differential receptor expression, differential receptor coupling to specific second-messenger generating systems, and different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79e5e560cf487a800a9c8d0e5e612b9
https://doi.org/10.1201/9781351070010-1
https://doi.org/10.1201/9781351070010-1
Autor:
Akira Matsumoto, Noriyasu Seki, Tadamitsu Kishimoto, Masato Kubo, J T Ransom, Akihiko Yoshimura, Jun Tsukada, Tetsuji Naka, Yoh Ichi Seki, Katsuhiko Hayashi
Publikováno v:
Proceedings of the National Academy of Sciences. 99:13003-13008
The development of helper T (Th) cell subsets, which secrete distinct cytokines, plays an important role in determining the type of immune response. The IL-4-mediated Janus kinase–signal transducer and activator of transcription signaling pathway i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b8b0f43b5c74a7ab67a025795271a9
https://doi.org/10.1073/pnas.202477099
https://doi.org/10.1073/pnas.202477099
Publikováno v:
Journal of Biological Chemistry. 269:19441-19446
Cyclosporin A-sensitive promoter activity that is induced by the T cell antigen receptor was identified in the region between base pairs -147 and -17 of the mouse interleukin (IL)-4 gene. Here, we identify a transcriptional factor, NF(P), that binds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3420decc6f500bbab9d99c70a26ffb83
https://doi.org/10.1016/s0021-9258(17)32188-9
https://doi.org/10.1016/s0021-9258(17)32188-9
Publikováno v:
The Journal of Immunology. 150:1746-1754
Activation of protein kinase C (PKC) in T cells leads to a variety of responses including IL-2 production and IL-2 receptor expression. PKC consists of several isoforms that exhibit some different in vitro properties. We have set up a Western blottin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6879af4b16b3aff2b56a45daca5484
https://doi.org/10.4049/jimmunol.150.5.1746
https://doi.org/10.4049/jimmunol.150.5.1746
Publikováno v:
Journal of Biological Chemistry. 266:11738-11745
We have studied Ca2+ mobilization mediated by the constitutively expressed muscarinic receptor on a subclone of PC-12 cells. The subclone, ACH2, was isolated with a flow cytometer by selection of single cells that exhibited a strong intracellular Ca2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d729fff97e1cdf6ffd57944708899e
https://doi.org/10.1016/s0021-9258(18)99019-8
https://doi.org/10.1016/s0021-9258(18)99019-8
Publikováno v:
Journal of Neurochemistry. 56:983-989
Single cell Ca2+ mobilization was studied by nonparametric, quantitative flow cytometry using a sort-selected subclone of PC-12 cells. The response of the parent PC-12 population to bradykinin (BK) was very heterogeneous and of a relatively low magni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271cb9590d461f3af62f818fd27db892
https://doi.org/10.1111/j.1471-4159.1991.tb02018.x
https://doi.org/10.1111/j.1471-4159.1991.tb02018.x
Publikováno v:
Cytometry. 43(3)
Plug flow cytometry is a recently developed system for the automated delivery of multiple small boluses or "plugs" of cells or particles to the flow cytometer for analysis. Important system features are that sample plugs are of precisely defined volu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1973c7e936e2bcd0721aa91a12f7eb7d
https://pubmed.ncbi.nlm.nih.gov/11170109
https://pubmed.ncbi.nlm.nih.gov/11170109
Autor:
H M, Cherwinski, R G, Cohn, P, Cheung, D J, Webster, Y Z, Xu, J P, Caulfield, J M, Young, G, Nakano, J T, Ransom
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(2)
Leflunomide is a novel immunosuppressive compound that is effective in the treatment of animal models of autoimmune disease and human rheumatoid arthritis. The mechanism of action is unknown. Here we show that leflunomide blocked 1) increases in nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e73377462f7e2718ce5d8a4508573288
https://pubmed.ncbi.nlm.nih.gov/7473131
https://pubmed.ncbi.nlm.nih.gov/7473131
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 44(8)
Leflunomide is an anti-inflammatory and immunosuppressive agent which blocks proliferation of transformed cells and mitogen stimulated normal lymphocytes but does not block T cell signalling mechanisms at antiproliferative concentrations. These prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f6d87b1187a004fc74fd71e2813a3f
https://pubmed.ncbi.nlm.nih.gov/8581517
https://pubmed.ncbi.nlm.nih.gov/8581517