Zobrazeno 1 - 10
of 88
pro vyhledávání: '"J. T. Poolman"'
Autor:
E M Rouppe van der Voort, Paul R. Langford, Martin L. Hibberd, C. A. Ison, Andrew J. Pollard, R Galassini, J S Kroll, Michael Levin, Robert Booy, J T Poolman, Simon Nadel
Publikováno v:
Europe PubMed Central
There is an urgent need for effective vaccines against serogroup B Neisseria meningitidis . Current experimental vaccines based on the outer membrane proteins (OMPs) of this organism provide a measure of protection in older children but have been ine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd6c445d6c3163d75f8c1d48f73b63f
https://ora.ox.ac.uk/objects/uuid:f8bbed6f-ddc2-46f4-a750-31a11d0acc62
https://ora.ox.ac.uk/objects/uuid:f8bbed6f-ddc2-46f4-a750-31a11d0acc62
Autor:
J. T. Poolman, Brian D. Plikaytis, Lambert S, J. Hackell, Ray Borrow, Elizabeth L. Miller, Ian M. Feavers, Nancy E. Rosenstein, B. Danve, Dan M. Granoff, Diana R. Martin, Wendell D. Zollinger, M. Blake, George M. Carlone, John B. Robbins, Rino Rappuoli, M. Caulfield, David S. Stephens, L. Danzig, Ingeborg S. Aaberge, L van Alphen
Publikováno v:
Vaccine. 24:5093-5107
Autor:
Paul R. Langford, C. A. Ison, Michael Levin, J T Poolman, Robert Booy, R Galassini, Simon Nadel, J S Kroll, Andrew J. Pollard, E M van der Voort
Publikováno v:
Europe PubMed Central
An understanding of the nature of immunity to serogroup B meningococci in childhood is necessary in order to establish the reasons for poor responses to candidate vaccines in infancy. We sought to examine the nature of humoral immune responses follow
Autor:
J van der Biezen, J T Poolman, H. H. van Dijken, Betsy Kuipers, Ivo J.T.M Claassen, E R van der Voort, P van der Ley, J Meylis
Publikováno v:
Infection and Immunity. 65:5184-5190
The PorA protein from Neisseria meningitidis, a potential vaccine candidate, induces human bactericidal antibodies which are serosubtype specific. We developed a hexavalent PorA outer membrane vesicle vaccine based on reference strain H44/76. This va
Autor:
E.M. Rouppe van der Voort, Carla C. A. M. Peeters, J T Poolman, A.J. Kuipers, L.C. Sundermann, P van der Ley, Margje Schuller, H.C. Rümke, J. Meulenbelt
Publikováno v:
Vaccine. 14:1009-1015
A meningococcal outer membrane vesicle (OMV) vaccine was prepared from two production strains designed to express three serosubtype-specific class 1 outer membrane proteins or PorA. The resulting hexavalent PorA OMV vaccine contained the serosubtypes
Autor:
Betsy Kuipers, E R van der Voort, O Tunnela, H. H. van Dijken, J T Poolman, Stephen L. George, J van der Biezen, P van der Ley
Publikováno v:
Infection and Immunity. 64:2745-2751
A set of isogenic strains was constructed from the meningococcal reference strain H44/76 (B:15:P1.7,16) which differed only in their outer membrane protein (OMP) compositions. First, three isogenic strains lacking the expression of either class 3 (Po
Publikováno v:
Microbial Pathogenesis. 17:395-408
The meningococcal lactoferrin receptor is a promising vaccine candidate since it seems to be antigenically rather stable. Monoclonal antibodies against this protein reacted with more than 50% of the strains tested. To gain further insight in its vari
Autor:
Rob J. P. M. Scholten, Jacob Dankert, J. T. Poolman, W. D. Zollinger, Hans A. Valkenburg, Betsy Kuipers
Publikováno v:
Journal of medical microbiology, 41(4), 236-243. Society for General Microbiology
Summary To assess the applicability of a whole-cell ELISA (WCE) with monoclonal antibodies (MAbs) for lipo-oligosaccharide (LOS) immunotyping of Neisseria meningitidis, 675 meningococcal isolates obtained in 1989 and 1990 in the Netherlands and 57 is
Autor:
C. A. P. Fijen, G. J. Coetzee, E. J. Van Schalkwyk, J. Dankert, J. T. Poolman, A. Orren, Dominique A. Caugant
Publikováno v:
Journal of Clinical Microbiology. 32:2185-2191
Complement deficiency has been associated with increased susceptibility to meningococcal disease. In order to determine whether special meningococcal strains caused disease in complement-deficient (CD) patients, 17 Neisseria meningitidis strains reco
Publikováno v:
Scopus-Elsevier
Nonhuman primates are often used as a model for studying vaccines for humans. However, it is not always clear how closely the antibody responses in these species mimic human responses. Recent studies have characterized the human antibody response to