Zobrazeno 1 - 10
of 104
pro vyhledávání: '"J. T. LaMont"'
Autor:
J T LaMont
Publikováno v:
European Surgery. 36:161-165
BACKGROUND: Clostridium difficile is one of the most prevalent hospital pathogens known with an attack rate of 20–25% in many American and European hospitals. METHODS: Review of experimental and clinical data on C. difficile colitis. RESULTS: The o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d2d44dc3c8829408021c3bcc3e4ec0f
https://doi.org/10.1007/s10353-004-0075-6
https://doi.org/10.1007/s10353-004-0075-6
Autor:
D C Laine, Michel Warny, Ciaran P. Kelly, C Pothoulakis, F Lebel, A Fatimi, E F Bostwick, J T LaMont
Publikováno v:
Gut. 44:212-217
BackgroundBovine immunoglobulin concentrate (BIC)-Clostridium difficile is prepared from the colostrum of cows immunised againstC difficile toxins and contains high concentrations of neutralising IgG antitoxin.AimsTo determine the proportion of BIC-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e046ca79054ea10a4e489d53dda6a5c
https://doi.org/10.1136/gut.44.2.212
https://doi.org/10.1136/gut.44.2.212
Autor:
J T Lamont, Daniel A. Leffler
Publikováno v:
Journal Club AINS. 4:194-195
Trotz vielfaltiger Bemuhungen, die Pravention und Therapie von Clostridium-difficile-Infektionen zu verbessern, verandern sich Inzidenz und Outcome kaum. Der vorliegende Review-Artikel von D. A. Leffle und T. Lamont vom Beth Israel Deaconess Medical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113dad609b59831be45658c7962dc4da
https://doi.org/10.1055/s-0035-1571022
https://doi.org/10.1055/s-0035-1571022
Autor:
J T LaMont, Ciaran P. Kelly
Publikováno v:
Annual Review of Medicine. 49:375-390
Clostridium difficile infection is associated with broad-spectrum antibiotic therapy and is the most common cause of infectious diarrhea in hospital patients. Pathogenic strains of C. difficile produce two protein exotoxins, toxin A and toxin B, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a2fcc1c6de35663f012e9e3d40645c
https://doi.org/10.1146/annurev.med.49.1.375
https://doi.org/10.1146/annurev.med.49.1.375
Autor:
Gerhard Hamilton, Roland Sedivy, G Bischof, Etienne Wenzl, Ignazio Castagliuolo, W Feil, Tacettin Sogukoglu, Martin Riegler, J. T. Lamont, Charalabos Pothoulakis, B Teleky, E. P. Cosentini
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 273:G1014-G1022
Epidermal growth factor (EGF) exhibits a cytoprotective effect on gastrointestinal epithelia via a receptor-mediated mechanism. We investigated the effect of EGF on Clostridium difficile toxin A (TxA)- and toxin B (TxB)-induced damage of human colon.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b39306a73bb912bdd8db69588d37c9
https://doi.org/10.1152/ajpgi.1997.273.5.g1014
https://doi.org/10.1152/ajpgi.1997.273.5.g1014
Autor:
Ciaran P. Kelly, Michel Warny, Ignazio Castagliuolo, C Pothoulakis, Sarah Keates, J Salcedo, J T LaMont
Publikováno v:
Scopus-Elsevier
Background—Many individuals have serum antibodies against Clostridium difficile toxins. Those with an impaired antitoxin response may be susceptible to recurrent, prolonged, or severe C difficile diarrhoea and colitis.Aims—To examine whether trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749be6574a40a3002c2247c10e4c88fe
https://doi.org/10.1136/gut.41.3.366
https://doi.org/10.1136/gut.41.3.366
Autor:
C Pothoulakis, TA Brasitus, Ignazio Castagliuolo, Ciaran P. Kelly, J T LaMont, U Galili, PK Dudeja, S Nikulasson
Publikováno v:
Gastroenterology. 110:1704-1712
BACKGROUND & AIMS: Nearly all human sera contain an immunoglobulin G antibody (antigalactose) that binds the trisaccharide Gal alpha 1-3Gal beta 1-4GlcNAc expressed on cells from most mammals but not humans. Because the Clostridium difficile toxin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f36984e5336f23a72d5292b3d31ede
https://doi.org/10.1053/gast.1996.v110.pm8964394
https://doi.org/10.1053/gast.1996.v110.pm8964394
Publikováno v:
Biochemical Journal. 308:89-96
Polyclonal antibodies raised to deglycosylated pig gastric mucin were used to screen a cDNA library constructed with pig stomach mucosal mRNA. Immunocytochemistry indicated that the antibody recognizes intracellular and secreted mucin in surface muco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4685588ee415f884fb089baf6827a71b
https://doi.org/10.1042/bj3080089
https://doi.org/10.1042/bj3080089
Autor:
E Cosentini, Martin Riegler, G Bischof, R. Schiessel, J T LaMont, Gerhard Hamilton, W Feil, J. Zacherl, R Sedivy, Charalabos Pothoulakis
Publikováno v:
Journal of Clinical Investigation. 95:2004-2011
Toxin A but not toxin B, appears to mediate intestinal damage in animal models of Clostridium difficile enteritis. The purpose of this study was to investigate the electrophysiologic and morphologic effects of purified C. difficile toxins A and B on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f17eb11fe3bb267b8601a4de4ef70e3
https://doi.org/10.1172/jci117885
https://doi.org/10.1172/jci117885
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 268:G487-G495
The principal cellular response to Clostridium difficile toxin B, a protein toxin associated with antibiotic-associated colitis, is the disassembly of actin microfilaments. Although receptor-activated signal transduction mechanisms have been proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dae9ef59618fcfedd3fb719df098ac6
https://doi.org/10.1152/ajpgi.1995.268.3.g487
https://doi.org/10.1152/ajpgi.1995.268.3.g487