Zobrazeno 1 - 10
of 73
pro vyhledávání: '"J. T. Flaherty"'
Autor:
James Ohr, Laura P. Stabile, Ann Marie Egloff, Lin Wang, P. Zhou, Jessica L. Geiger, Jennifer R. Grandis, J. T. Flaherty, Natalie J. Rothenberger, Julie E. Bauman, William E. Gooding, Michael K. Gibson
Objective Src family kinase (SFK) activation circumvents epidermal growth factor receptor (EGFR) targeting in head and neck squamous cell carcinoma (HNSCC); dual SFK-EGFR targeting could overcome cetuximab resistance. Patients and methods We conducte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b1b344ad0e67c1f2baa69491b87dd3
https://escholarship.org/uc/item/1g89s36c
https://escholarship.org/uc/item/1g89s36c
Autor:
J. T. Flaherty, M. K. Gibson, Jennifer R. Grandis, Laura P. Stabile, Julie E. Bauman, William E. Gooding, Jessica L. Geiger, James Ohr, Ann Marie Egloff
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 94:930
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a143772f12c758f4c20e6d91f1110e8
https://doi.org/10.1016/j.ijrobp.2015.12.242
https://doi.org/10.1016/j.ijrobp.2015.12.242
Autor:
J. T. Flaherty, Giuseppe E. Santoro, P. P. Elia, Isabella Tritto, Mario Condorelli, Giuseppe Ambrosio, Massimo Chiariello, Carlo Duilio
Publikováno v:
Journal of Clinical Investigation. 87:2056-2066
To test whether generation of oxygen radicals during postischemic reperfusion might promote peroxidation of cardiac membrane lipids, four groups of Langendorff-perfused rabbit hearts were processed at the end of (a) control perfusion, (b) 30 min of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6664b365e1a71968c533a853b3bd52
https://doi.org/10.1172/jci115236
https://doi.org/10.1172/jci115236
Autor:
C P, Cannon, A, Battler, R G, Brindis, J L, Cox, S G, Ellis, N R, Every, J T, Flaherty, R A, Harrington, H M, Krumholz, M L, Simoons, F J, Van De Werf, W S, Weintraub, K R, Mitchell, S L, Morrisson, H V, Anderson, D S, Cannom, W R, Chitwood, J E, Cigarroa, R L, Collins-Nakai, R J, Gibbons, F L, Grover, P A, Heidenreich, B K, Khandheria, S B, Knoebel, H L, Krumholz, D J, Malenka, D B, Mark, C R, Mckay, E R, Passamani, M J, Radford, R N, Riner, J B, Schwartz, R E, Shaw, R J, Shemin, D B, Van Fossen, E D, Verrier, M W, Watkins, D R, Phoubandith, T, Furnelli
Publikováno v:
Journal of the American College of Cardiology. 38(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::910db1389b096761dde6e1179212515d
https://pubmed.ncbi.nlm.nih.gov/11738323
https://pubmed.ncbi.nlm.nih.gov/11738323
Autor:
J. T. Flaherty, Giuseppe Ambrosio
Publikováno v:
Cardiovascular drugs and therapy. 6(6)
Hydroxyl radical formation, secondary to superoxide radical generation, has been advocated as the actual mechanism of oxygen radical-mediated damage in biological systems. The present study was designed to compare the efficacy of administration of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a421e53bc0c9f49050d4087f91490329
https://pubmed.ncbi.nlm.nih.gov/1337978
https://pubmed.ncbi.nlm.nih.gov/1337978
Autor:
J. L. Zweier, J. T. Flaherty
Publikováno v:
Klinische Wochenschrift. 69(21-23)
Timely reperfusion with intravenous thrombolytic agents has been shown to reduce mortality in patients with acute myocardial infarction. However, the magnitude of improvement in left ventricular function has always been less than expected. Reperfusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230c8ed0a0cbef23d7fa497273a44bf8
https://pubmed.ncbi.nlm.nih.gov/1798280
https://pubmed.ncbi.nlm.nih.gov/1798280
Autor:
J M, Kirshenbaum, R D, Bahr, J T, Flaherty, V, Gurewich, H J, Levine, J, Loscalzo, R R, Schumacher, E J, Topol, D W, Wahr, E, Braunwald
Publikováno v:
The American journal of cardiology. 68(17)
The effect of simultaneous infusions of low-dose recombinant tissue-type plasminogen activator (t-PA) and single-chain urokinase-type plasminogen activator (scu-PA, pro-urokinase) on coronary arterial thrombolysis was investigated in 23 patients trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82ac44f68c64b3580bacd27123b81db9
https://pubmed.ncbi.nlm.nih.gov/1746455
https://pubmed.ncbi.nlm.nih.gov/1746455
Publikováno v:
Circulation. 83(3)
BACKGROUND Iron may play a central role in oxygen radical generation during myocardial ischemia and after reperfusion. Because conditions during ischemia may also liberate iron, we hypothesized that administration of the iron chelator deferoxamine du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1435827d3b6a6aca3c7d659fa36c7d5f
https://pubmed.ncbi.nlm.nih.gov/1999020
https://pubmed.ncbi.nlm.nih.gov/1999020
Autor:
S O, Gottlieb, J T, Flaherty
Publikováno v:
Cardiology clinics. 9(1)
The pathophysiologic mechanisms responsible for the clinical syndrome known as unstable angina pectoris are complex but provide a framework for a rational medical approach to this ischemic condition. The combined use of nitrates, beta-blockers, calci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a313f7a6a587763c71eeb3cac498ca40
https://pubmed.ncbi.nlm.nih.gov/1674228
https://pubmed.ncbi.nlm.nih.gov/1674228
Oxygen radical toxicity has been implicated in the pathogenesis of myocardial reperfusion injury. In the present study we sought to document the existence of a precise temporal relationship between the time course of free radical generation and the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5527bcd28876f72409a480f1033d261e
http://hdl.handle.net/11391/915860
http://hdl.handle.net/11391/915860