Zobrazeno 1 - 10
of 32
pro vyhledávání: '"J. T. Elder"'
Autor:
C. Enerbäck, C. Sandin, S. Lambert, M. Zawistowski, P. E. Stuart, D. Verma, L. C. Tsoi, R. P. Nair, A. Johnston, J. T. Elder
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-6 (2018)
Abstract Tyrosine kinase 2 (TYK2) belongs to the Janus kinase (JAK) family of tyrosine kinases, which transmit signals from activated cytokine receptors. GWAS have consistently implicated TYK2 in psoriasis susceptibility. We performed an in-depth ass
Externí odkaz:
https://doaj.org/article/61869092989048ecba2bb37bc73b11ed
Autor:
P. E. Stuart, R. P. Nair, R. Hiremagalore, P. Kullavanijaya, T. Tejasvi, H. W. Lim, J. J. Voorhees, J. T. Elder
Publikováno v:
Tissue Antigens. 76:387-397
Earlier studies have shown that psoriasis in Japan and Thailand is associated with two different major histocompatibility complex (MHC) haplotypes - those bearing HLA-Cw6 and those bearing HLA-Cw1 and HLA-B46. In an independent case-control sample fr
Publikováno v:
Skin Pharmacology and Physiology. 18:123-131
Psoriatic plaque skin incubated for eight days in organ culture in the presence of a potent epidermal growth factor (EGF) receptor tyrosine kinase (RTK) antagonist reverted to a more normal histological appearance, while untreated psoriatic plaque sk
Autor:
R R, Graham, C D, Langefeld, P M, Gaffney, W A, Ortmann, S A, Selby, E C, Baechler, K B, Shark, T C, Ockenden, K E, Rohlf, K L, Moser, W M, Brown, S E, Gabriel, R P, Messner, R A, King, P, Horak, J T, Elder, P E, Stuart, S S, Rich, T W, Behrens
Publikováno v:
Arthritis Research
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies to a wide range of self-antigens. Recent genome screens have implicated numerous chromosomal regions as potential SLE susceptibility
Autor:
J. T. Elder
Publikováno v:
Archives of Dermatology. 130:216-224
Autor:
K D Cooper, C Hammerberg, O Baadsgaard, J T Elder, L S Chan, D N Sauder, J J Voorhees, G Fisher
Publikováno v:
The Journal of Immunology. 144:4593-4603
IL-1 may influence or be influenced by a number of abnormalities present in psoriasis; including keratinocyte proliferation, eicosanoid production, fibroblast activation, endothelial cell adhesiveness, T cell infiltration and activation, cyclic nucle
Autor:
J. T. Elder
Publikováno v:
Archives of Dermatology. 126:379-382
Autor:
S W, Stoll, N V, Chia, R P, Nair, T L, Woods, P, Stuart, T, Henseler, S, Jenisch, E, Christophers, J J, Voorhees, J T, Elder
Publikováno v:
Clinical and experimental dermatology. 26(1)
Psoriasis is a chronic inflammatory skin disease with a strong genetic component. Linkage studies have identified several susceptibility loci for psoriasis including a region on chromosome 1q21 termed the 'epidermal differentiation complex'. At least
Publikováno v:
The Journal of investigative dermatology. 115(3)
S100A2 is a calmodulin-like protein of unknown function, whose transcription is positively regulated in response to ErbB and p53 signaling. Expression of S100A2 is markedly increased in the context of ErbB-driven reactive epidermal hyperplasia, and d