Zobrazeno 1 - 10
of 127
pro vyhledávání: '"J. T. Dingle"'
Autor:
J T Dingle
Publikováno v:
Zeitschrift f�r Rheumatologie. 58:125-129
The present paper presents data obtained over a 12 year period, on the matrix synthesis and turnover in some 650 arthritic and 180 non-arthritic (N) human cartilages using a standardised in vitro method. When the relative metabolic (synthetic/repair
Autor:
J. T. Dingle, M. Parker
Publikováno v:
Clinical Drug Investigation. 14:353-362
In terms of their effects on matrix synthesis by the indigenous chondrocytes of human articular cartilage, it has been suggested that NSAIDs fall into three categories: those exemplified by aceclofenac and tenidap that are capable of stimulating matr
Autor:
Kathy M. O'Boyle, Andrew Harkin, B. F. Leek, Peter McLoughlin, R. A. Padua, M. Leek, M. Garrett, A. Watson, C. G. Lyons, C. S. Downes, D. Cantillon, B. A. O. McCormack, P. Quinn, Alan Carr, Margaret Griffin, Thomas F. Gorey, T. Ruane, John J. O'Connor, D. J. Wilcox, T. M. Dineen, P. N. Convery, G. O’Cuinn, Damian P. O’Connell, C-A. Frazer, S. Thornton, Jmcc Anderson, D. M. P. Morrow, K. Scott, D. M. Walsh, O. P. Friery, W. Quinlan, D. M. Burns, J. R. Docherty, C. P. Halligan, Jacqueline M. O'Connor, R. Moran, Edward R. Perl, J. P. Ryan, D. Harvey, F. S. Fay, C. Higgins, T. J. Connor, E. Arendt, R. M. Drummond, Brian E. Leonard, D. Fitzpatrick, L. A. J. O’Neill, P. R. O'Connell, E. S. Galligan, P. M. Murchan, A. Rizvi, R. J. Delicata, K. Søballe, Momna Hejmadi, D. G. Hirst, A. S. Lowe, D. P. Campion, S. Dudeney, T. Robson, John F. Cryan, C. L. Brady, D. S. Soppitt, Brian J. Harvey, B. Schreiber, G. J. Dempsey, Valerie J. McKelvey-Martin, Deborah A. Brown, C. Lally, J. C. McGrath, I. Hill, C. M. G. Thompson, S. Mehdi, P. D. Carey, C. J. O’Boyle, A. Greer, M. H. Esfandiary, T. Quinn, J. R. Bailie, T. P. J. Hennessy, K. R. Milligan, T. Dineen, M. M. Murray, F. Lynch, M. Dumbleton, K. A. Fitzgerald, M. McCarthy, Anthony William Sharpe Watson, John P. Kelly, James Allen, J. Carson, Noel G. McHale, A. M. Redmond, A. Dunne, Austin Leahy, K. Abdullah, Timothy M. McGloughlin, M. C. Mukunda, D. E. Beverland, A. K. Keenan, A. O’Farrell, A. Nolan, G. B. Nevin, Alex Lennon, John Orr, James A. Robinson, J. B. Macmillan, T. N. Walsh, Kevin M. Joyce, J. P. Mulville, S. Maher, K. T. Gavin, Stephanie R. McKeown, R. Powell, J. O’Byrne, David Bouchier-Hayes, S. T. O’Sullivan, L. Brennan, Nicholas Dunne, S. K. Smith, M MacDermott, C. Simms, M. Cashman, K. O’Rourke, Ken D. O'Halloran, C. Thompson, B. M. Flavin, Dervla O'Malley, D. Lloyds, G. Wilson, T. P. F. O’Connor, A. Devitt, S. Ní Aodha, M. G. O. Riordain, N. O’Connor, M. O’Shaughnessy, Patrick J. Prendergast, G. R. Wasson, A. Jenkinson, Bernadette M. Hannigan, B. Higgins, J. J. Strain, E. V. Davies, K. J. Brady, R. G. O’Regan, J. T. Dingle, J. Panchal, J. Rice, J. Rothwell, Michael Carey, Michelle K. McGuire, L. Noelke, Aidan Bradford, A. J. McShane, J. M. O’Donoghue, A. K. Curran, L. Doherty, P. A. Kelly, R. Dwyer, James A. Houghton, G. D. Kennovin, Deirdre M O'Leary, William S. Gilmore, Tim O'Brien, B. Van Hemelrijk, Brian Caulfield, P. Fanning, M. Sweeney, B. Lew, T. Mubarak Abujaffom, J. G. McCarron, K. D. Cotton, S McGrath, J. G. McGeown, J. C. W. Brown, A. P. Moran, K. U. O’Kelly, E. Healy, Keith D. Thornbury, G. D. Baxter, D. McCormack, C. Galvin, L. Gilmartin, Maxine P. Bonham, M. Harbinson, C. Connolly, Y. Ikadi, C. S. Regan, G. Noble, J. Shine, C. J. Kelly, S. Z. Imam, H-C. McKillen, J. Macfie, M. C. Regan, E. J. Petitt, A. A. J. Adgey, Andrew N. Coogan, R. G. K. Watson, Mark A. Hollywood, J. L. Leckey, W. J. Hatton, T. Barry, M. Browne, C. J. Mitchell, S. Atkinson, M. P. Ryan, J. Monaghan, G. T. McMahon, M. A. Cox, G. P. Love, C. A. Higgins, A. H. Baker, N. Cregg, G. McKerr, A. McElligott, Laurence H. Patterson, Ciaran MacDonncha, F. Markos, W. Ruddock, R. Huiskes, A. Bird, J. P. H. Fee, W. J. Hall, J. Kilbride, Hugh McGlynn, C. W. Taylor, David Taylor, D. J. Buckley, J. Flaherty, T. Prenderville, Robert G. Hill, T. C. Lee, Jennifer M. Walsh, K. M. Smith, J. Lewis, A. D. Martin, John M. Fitzpatrick
Publikováno v:
Irish Journal of Medical Science. 166:157-194
Publikováno v:
InflammoPharmacology. 2:25-35
It is now recognized that indomethacin, a frequently prescribed non-steroidal anti-inflammatory drug, may itself exert detrimental effects on cartilage matrix metabolism. In this study, the effects of indomethacin on one aspect of chondrocyte behavio
Publikováno v:
The Journal of clinical investigation. 26(6)
Publikováno v:
Cell Biochemistry and Function. 9:99-102
The damage to articular cartilage, characteristic of arthritic disease, is usually ascribed to increased degradative activity by enzymes or free radicals from locally activated cells.1–3 We propose that inhibition of matrix synthesis, and consequen
Autor:
J. T. Dingle
Publikováno v:
Ciba Foundation Symposium 11-Hard Tissue Growth, Repair and Remineralization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d848a5b23d8d9e73e73b93fb35b9c620
https://doi.org/10.1002/9780470719947.ch14
https://doi.org/10.1002/9780470719947.ch14
Autor:
J. T. Dingle
Publikováno v:
Ciba Foundation Symposium-Lysosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18997d37837f3c614931395f5808df5
https://doi.org/10.1002/9780470715314.ch15
https://doi.org/10.1002/9780470715314.ch15
Publikováno v:
Annals of the Rheumatic Diseases. 49:889-892
Interleukin-1 activated chondrocytes have been identified in pig articular cartilage by immunolocalisation using a polyclonal antiserum recognising cytokine induced surface epitopes. Although chondrocytes with membrane staining were noted in all zone
Publikováno v:
Rheumatology. 29:340-344
Proteoglycan levels were measured in a series of synovial fluid samples from patients with acute and chronic joint diseases using a modified chemical dye binding method. Levels found in 50 miscellaneous inflammatory arthritis fluids (mean = 173.2 +/-