Zobrazeno 1 - 10
of 1 170
pro vyhledávání: '"J. Suckling"'
Autor:
J. M. Gorriz, J. Ramirez, J. Suckling, Ignacio Alvarez Illan, Andres Ortiz, F. J. Martinez-Murcia, Fermin Segovia, D. Salas-Gonzalez, Shuihua Wang
Publikováno v:
IEEE Access, Vol 5, Pp 11468-11478 (2017)
Machine learning has been successfully applied to many areas of science and engineering. Some examples include time series prediction, optical character recognition, signal and image classification in biomedical applications for diagnosis and prognos
Externí odkaz:
https://doaj.org/article/8e92fdb891104e8fbc472c71fadd4fdf
Autor:
M.G. Hart, C.R. Housden, J. Suckling, R. Tait, A. Young, U. Müller, V.F.J. Newcombe, I. Jalloh, B. Pearson, J. Cross, R.A. Trivedi, J.D. Pickard, B.J. Sahakian, P.J. Hutchinson
Publikováno v:
NeuroImage: Clinical, Vol 15, Iss , Pp 194-199 (2017)
Background/aim: The safety of amateur and professional boxing is a contentious issue. We hypothesised that advanced magnetic resonance imaging and neuropsychological testing could provide evidence of acute and early brain injury in amateur boxers. Me
Externí odkaz:
https://doaj.org/article/596d27fd47b54a2dbd0601038e760c6d
Autor:
R.L. Moseley, R.J.F. Ypma, R.J. Holt, D. Floris, L.R. Chura, M.D. Spencer, S. Baron-Cohen, J. Suckling, E. Bullmore, M. Rubinov
Publikováno v:
NeuroImage: Clinical, Vol 9, Iss C, Pp 140-152 (2015)
Endophenotypes are heritable and quantifiable markers that may assist in the identification of the complex genetic underpinnings of psychiatric conditions. Here we examined global hypoconnectivity as an endophenotype of autism spectrum conditions (AS
Externí odkaz:
https://doaj.org/article/f8b723dad57547c4b519b6e2d3e72e86
Autor:
Christopher Riley, Usama Ammar, Aisha Alsfouk, Nahoum G. Anthony, Jessica Baiget, Giacomo Berretta, David Breen, Judith Huggan, Christopher Lawson, Kathryn McIntosh, Robin Plevin, Colin J. Suckling, Louise C. Young, Andrew Paul, Simon P. Mackay
Publikováno v:
Molecules, Vol 29, Iss 15, p 3515 (2024)
The inhibitory-kappaB kinases (IKKs) IKKα and IKKβ play central roles in regulating the non-canonical and canonical NF-κB signalling pathways. Whilst the proteins that transduce the signals of each pathway have been extensively characterised, the
Externí odkaz:
https://doaj.org/article/e3e2e03e3b834ed6981a0d5113267e5c
Autor:
Anna K. Forbes, William Hinton, Michael D. Feher, William Elson, Mark Joy, José M. Ordóñez-Mena, Xuejuan Fan, Nicholas I. Cole, Debasish Banerjee, Rebecca J. Suckling, Simon de Lusignan, Pauline A. Swift
Publikováno v:
EClinicalMedicine, Vol 68, Iss , Pp 102426- (2024)
Summary: Background: The cardiovascular and kidney benefits of sodium-glucose co-transporter-2 (SGLT2) inhibitors in people with chronic kidney disease (CKD) are well established. The implementation of updated SGLT2 inhibitor guidelines and prescribi
Externí odkaz:
https://doaj.org/article/e0baed73b1194984b55afe9edc737587
Autor:
Margaret M. Harnett, Felicity E. Lumb, Jenny Crowe, James Doonan, Geraldine Buitrago, Stephanie Brown, Gillian Thom, Amy MacDonald, Colin J. Suckling, Colin Selman, William Harnett
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Mice develop pathology in the lungs as they age and this may be accelerated by a high calorie diet (HCD). ES-62 is a protein secreted by the parasitic worm Acanthocheilonema viteae that is immunomodulatory by virtue of covalently attached phosphorylc
Externí odkaz:
https://doaj.org/article/e3ecfaf3645f4e8596b6d32606f6e458
Autor:
Margaret M. Harnett, James Doonan, Felicity E. Lumb, Jenny Crowe, Roel Olde Damink, Geraldine Buitrago, Josephine Duncombe-Moore, Debbie I. Wilkinson, Colin J. Suckling, Colin Selman, William Harnett
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite significant increases in human lifespan over the last century, adoption of high calorie diets (HCD) has driven global increases in type-2 diabetes, obesity and cardiovascular disease, disorders precluding corresponding improvements in healths
Externí odkaz:
https://doaj.org/article/523ab5246f8f4ce380e052b716596cff
Autor:
Marlene Corbet, Miguel A Pineda, Kun Yang, Anuradha Tarafdar, Sarah McGrath, Rinako Nakagawa, Felicity E Lumb, Colin J Suckling, William Harnett, Margaret M Harnett
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010069 (2021)
ES-62 is the major secreted protein of the parasitic filarial nematode, Acanthocheilonema viteae. The molecule exists as a large tetramer (MW, ~240kD), which possesses immunomodulatory properties by virtue of multiple phosphorylcholine (PC) moieties
Externí odkaz:
https://doaj.org/article/9eed3db2dce240c7ac1544eba08ed52c
Autor:
Charlotte Hind, Melanie Clifford, Charlotte Woolley, Jane Harmer, Leah M. C. McGee, Izaak Tyson-Hirst, Henry J. Tait, Daniel P. Brooke, Stephanie J. Dancer, Iain S. Hunter, Colin J. Suckling, Rebecca Beveridge, John A. Parkinson, J. Mark Sutton, Fraser J. Scott
Publikováno v:
ACS Infectious Diseases. 8:2552-2563
MGB-BP-3 is a potential first-in-class antibiotic, a Strathclyde Minor Groove Binder (S-MGB), that has successfully completed Phase IIa clinical trials for the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd40ee75d50fe78bef77a7f42c5f6f2
https://doi.org/10.1021/acsinfecdis.2c00445
https://doi.org/10.1021/acsinfecdis.2c00445
Autor:
Anna K. Forbes, Rebecca J. Suckling, William Hinton, Michael D. Feher, Debasish Banerjee, Nicholas I. Cole, Simon de Lusignan, Pauline A. Swift
Publikováno v:
Diabetes, Obesity and Metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f79d4798e06312e208709ca8336fb104
https://doi.org/10.1111/dom.15111
https://doi.org/10.1111/dom.15111