Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J. Stefan Kaczmarek"'
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 9, Pp 526-537 (2020)
Abstract Cystic Fibrosis (CF), an inherited multi‐system disease, is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) that disrupt its ability to secrete anions from epithelia. Recovery of functional anion secre
Externí odkaz:
https://doaj.org/article/226b8725f8634eb099cd8b16bb7bd856
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 9, Pp 526-537 (2020)
FASEB BioAdvances
FASEB BioAdvances
Cystic Fibrosis (CF), an inherited multi‐system disease, is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) that disrupt its ability to secrete anions from epithelia. Recovery of functional anion secretion may
Autor:
Serdar Uysal, Jochen K. Lennerz, J. Stefan Kaczmarek, Antonio Riccio, David E. Clapham, Alexander Hein, Andrea S. Link, Katharina Zimmermann, John D. Pfeifer, Markus Delling
Publikováno v:
Proceedings of the National Academy of Sciences. 108:18114-18119
Detection and adaptation to cold temperature is crucial to survival. Cold sensing in the innocuous range of cold (>10–15 °C) in the mammalian peripheral nervous system is thought to rely primarily on transient receptor potential (TRP) ion channels
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(20)
The nonselective cation channel transient receptor potential canonical (TRPC)5 is found predominantly in the brain and has been proposed to regulate neuronal processes and growth cones. Here, we demonstrate that semaphorin 3A-mediated growth cone col
Publikováno v:
The Journal of General Physiology
TRPC5 is a calcium (Ca(2+))-permeable nonselective cation channel expressed in several brain regions, including the hippocampus, cerebellum, and amygdala. Although TRPC5 is activated by receptors coupled to phospholipase C, the precise signaling path
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(18)
Granulocytes generate a “respiratory burst” of NADPH oxidase-dependent superoxide anion (O 2 −∙ ) production that is required for efficient clearance of bacterial pathogens. Hv1 mediates a voltage-gated H + channel activity that is proposed t
Autor:
Jayhong A. Chong, Magdalene M. Moran, Robert G. Roeder, Martin Teichmann, J. Stefan Kaczmarek, David E. Clapham
The lack of direct targets for TATA-binding protein (TBP)-like factors (TLFs) confounds the understanding of their role in gene expression. Here we report that human TLF (also called TBP-related factor 2 [TRF2]) activates a number of different genes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d584b918cce9600b3e7dccf349a43e
https://europepmc.org/articles/PMC1061635/
https://europepmc.org/articles/PMC1061635/
Akademický článek
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Autor:
Bajko, Jeffrey1 (AUTHOR), Duguid, Mei1 (AUTHOR), Altmann, Steve1 (AUTHOR), Hurlbut, Gregory D.1 (AUTHOR), Kaczmarek, J. Stefan1 (AUTHOR) stefan@carawaytx.com
Publikováno v:
FASEB Bioadvances. Sep2020, Vol. 2 Issue 9, p526-537. 12p.
Autor:
Moran, Magdalene M.1, Szallasi, Arpad2 arpad.szallasi@bmcjax.com
Publikováno v:
British Journal of Pharmacology. 6/15/2018, Vol. 175 Issue 12, p2185-2203. 19p. 5 Diagrams.