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Akademický článek

Insights from molecular docking and molecular dynamics on the potential of vitexin as an antagonist candidate against lipopolysaccharide (LPS) for microglial activation in neuroinflammation

Autor: M. A. F. Yahaya, A. R. Abu Bakar, J. Stanslas, N. Nordin, M. Zainol, M. Z. Mehat

Publikováno v: BMC Biotechnology, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract Background Neuroinflammation has been identified to be the key player in most neurodegenerative diseases. If neuroinflammation is left to be unresolved, chronic neuroinflammation will be establish. Such situation is due to the overly-activat

Externí odkaz: https://doaj.org/article/ed061a236b7043908142f5709b790f4f

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Akademický článek

Edible Bird Nest Protects the Kidney From Gentamicin Induced Acute Tubular Necrosis

Autor: Christopher T S. Lim, Norhafizah M., D. Sani, S. N. Tan, C. W. Lim, Brian P. Kirby, A. Ideris, J. Stanslas

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Every year, there are about 13.3 million cases of acute kidney injury (AKI). Although AKI is a preventable and treatable disease, if left untreated, it has high risk of multiple organ failure and progression to end stage kidney disease. Acute tubular

Externí odkaz: https://doaj.org/article/2cb8d130f09a459892196b5c2e15b5f6

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Akademický článek

Possible Epigenetic Role of Vitexin in Regulating Neuroinflammation in Alzheimer’s Disease

Autor: M. A. F. Yahaya, S. Z. I. Zolkiffly, M. A. M. Moklas, H. Abdul Hamid, J. Stanslas, M. Zainol, M. Z. Mehat

Publikováno v: Journal of Immunology Research, Vol 2020 (2020)

Alzheimer’s disease (AD) has been clinically characterized by a progressive degeneration of neurons which resulted in a gradual and irreversible cognitive impairment. The accumulation of Aβ and τ proteins in the brain contribute to the severity o

Externí odkaz: https://doaj.org/article/6c1d407803a14c379b560596a16e70a4

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Akademický článek

Abnormal Proteins in Primary Breast Cancer Tissues from 25 Sudanese Patients

Autor: M.E. Ahamed, M.E. Ahmed, A.M. Eltoum, G.O. Altahir, K.M. Ahmed, S.O. Harbi, J. Stanslas, A.O. Mohamed

Publikováno v: European Journal of Inflammation, Vol 6 (2008)

This study was designed to compare antigen content of normal with cancerous breast tissues from Sudanese patients. Fifty tissue samples (normal and cancerous) from 25 Sudanese patients with primary breast cancer were analyzed for their protein conten

Externí odkaz: https://doaj.org/article/ec6a70d0bae24ee49c3eabd67945d5ad

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Akademický článek

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Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Pancreatic cancer treatment with targeted therapies: are we there yet?

Autor: O, Ngozi Nwaefulu, S, Rao Sagineedu, M, Kaisarul Islam, J, Stanslas

Publikováno v: European review for medical and pharmacological sciences. 26(2)

Pancreatic cancer (PaCa) is a disease that is extremely difficult to treat and is associated with a high fatality rate. The majority of patients present to hospitals with metastatic or end-stage cancer, making the ultimate cure impossible. End-stage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91f08ee558eeb5623cf8de173ac11fb2
https://pubmed.ncbi.nlm.nih.gov/35113412

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Correlation of whole blood hydroxychloroquine concentration with cutaneous lupus erythematosus and factors associated with it: First multicenter, cross-sectional analysis in Malaysia

Autor: D. Peh, W. S. L. Wan Ahmad Kammal, P. J. Beh, A. C. H. Yong, W. C. Tan, A. L. Lim, S. Thevarajah, J. Stanslas, Kang Nien How

Publikováno v: The Journal of dermatologyREFERENCES. 49(5)

Hydroxychloroquine (HCQ) is the first-line systemic treatment for cutaneous lupus erythematosus (CLE). Whole blood HCQ concentration (WBHCQ) was found to correlate with CLE severity among Caucasians. However, studies on Asians are scarce. We aim to e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c417a37ac3cd90f1014e193dfff306
https://pubmed.ncbi.nlm.nih.gov/35067938

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Akademický článek

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Toxicological and pharmacokinetic analysis at therapeutic dose of SRS27, an investigational anti-asthma agent

Autor: J C W, Lim, S R, Sagineedu, A C H, Yong, S M, Sidik, W S F, Wong, J, Stanslas

Publikováno v: Naunyn-Schmiedeberg's archives of pharmacology. 394(1)

SRS27, an andrographolide analogue, had been proven to have therapeutic properties at a dose of 3 mg/kg in both in vitro and in vivo asthma models of our previous study. The present study focuses on the pharmacokinetic and toxicity profile of this co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::197dd998d28255515f5142be2f0b4b8b
https://pubmed.ncbi.nlm.nih.gov/32840650

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