Zobrazeno 1 - 10
of 465
pro vyhledávání: '"J. Skelly"'
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma. The intravascular worms acquire the nutrients necessary for their survival from host blood. Since all animals are auxotrophic for riboflavin (vi
Externí odkaz:
https://doaj.org/article/e317cf90d47b4fb0a04b7edd9fb6f283
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28271- (2024)
Schistosomes are intravascular parasitic worms infecting >200 million people globally. Here we examine how the worms acquire an essential nutrient - vitamin B2 (riboflavin). We demonstrate that all intravascular life stages (schistosomula, adult male
Externí odkaz:
https://doaj.org/article/35428c9b62ce4f85a3db1ef102dfa05a
Autor:
Jason P. Bestwick, Barbara J. Skelly, James W. Swann, Barbara Glanemann, Nick Bexfield, Zeta Gkoka, David J. Walker, Paolo Silvestrini, Sophie Adamantos, Mayank Seth, James Warland
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 4, Pp 1267-1280 (2022)
Abstract Background Current reports about the use of splenectomy for the management of immune‐mediated hemolytic anemia (IMHA) or immune‐mediated thrombocytopenia (ITP) or both in dogs are limited. Objectives To retrospectively describe the use o
Externí odkaz:
https://doaj.org/article/999755ca02e04c4bbdbcc3bdff03fae4
Autor:
Mamoru Matsumura, Mika Nomoto, Tomotaka Itaya, Yuri Aratani, Mizuki Iwamoto, Takakazu Matsuura, Yuki Hayashi, Tsuyoshi Mori, Michael J. Skelly, Yoshiharu Y. Yamamoto, Toshinori Kinoshita, Izumi C. Mori, Takamasa Suzuki, Shigeyuki Betsuyaku, Steven H. Spoel, Masatsugu Toyota, Yasuomi Tada
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Plant immunity can be induced by pathogen signals or environmental cues. Here, the authors show that plant leaves use trichomes to sense incoming raindrops and trigger basal defence responses to protect against subsequent microbial infection.
Externí odkaz:
https://doaj.org/article/7bde799e31584043b4130c612c3a4b00
Autor:
Jason P. Bestwick, Mellora Sharman, Nat T. Whitley, Caroline Kisielewicz, Barbara J. Skelly, Simon Tappin, Lindsay Kellett‐Gregory, Mayank Seth
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 1, Pp 78-85 (2022)
Abstract Background The IV use of human immunoglobulin (hIVIG) in dogs with primary immune‐mediated hemolytic anemia (IMHA) has been described previously, but herein we describe the use of high‐dose IgM‐enriched hIVIG (Pentaglobin). Hypothesis/
Externí odkaz:
https://doaj.org/article/24e0e9bd8c474e82b73ae4447bc925e3
Autor:
Patrick J. Skelly, Akram A. Da’dara
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Schistosomes are long-lived parasitic worms that infect >200 million people globally. The intravascular life stages are known to display acetylcholinesterase (AChE) activity internally as well as, somewhat surprisingly, on external tegumental membran
Externí odkaz:
https://doaj.org/article/c8f1ef2a98b64216a191681618ac716a
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 568-579 (2020)
Infection with intravascular platyhelminths of the genus Schistosoma can result in the debilitating disease schistosomiasis. Schistosomes (blood flukes) can survive in the host for many years. We hypothesize that proteins on their host-interactive su
Externí odkaz:
https://doaj.org/article/4783348f8ee441e7ada5d28a2f1dea9c
Autor:
Mika Nomoto, Michael J. Skelly, Tomotaka Itaya, Tsuyoshi Mori, Takamasa Suzuki, Tomonao Matsushita, Mutsutomo Tokizawa, Keiko Kuwata, Hitoshi Mori, Yoshiharu Y. Yamamoto, Tetsuya Higashiyama, Hironaka Tsukagoshi, Steven H. Spoel, Yasuomi Tada
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110125- (2021)
Summary: Plants tailor immune responses to defend against pathogens with different lifestyles. In this process, antagonism between the immune hormones salicylic acid (SA) and jasmonic acid (JA) optimizes transcriptional signatures specifically to the
Externí odkaz:
https://doaj.org/article/d575314146ef4b3891d564a75cb63cb9
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010064 (2021)
Schistosomes are long lived, intravascular parasitic platyhelminths that infect >200 million people globally. The molecular mechanisms used by these blood flukes to dampen host immune responses are described in this review. Adult worms express a coll
Externí odkaz:
https://doaj.org/article/60f39ca0b17449658bb9c14ab52cc075
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Fructose 1,6-bisphosphate aldolase is a ubiquitous cytosolic enzyme that catalyzes the fourth step of glycolysis. Aldolases are classified into three groups: Class-I, Class-IA, and Class-II; all classes share similar structural features but low amino
Externí odkaz:
https://doaj.org/article/c82f883841ad4da58ec921860ea73b77