Cancer incidence following non-neoplastic medical conditions: a prospective population-based cohort study

Autor: Lauri J. Sipilä, Tomas Tanskanen, Sanna Heikkinen, Karri Seppä, Mervi Aavikko, Janne Ravantti, Lauri A. Aaltonen, Janne Pitkäniemi

Publikováno v: Acta Oncologica, Vol 63, Iss 1 (2024)

Background and purpose: Many non-neoplastic diseases have been established to be tumorigenic, and cancers are sometimes misdiagnosed as non-neoplastic diseases. We conducted a comprehensive registry-based study of site-specific cancer diagnosis risk

Externí odkaz: https://doaj.org/article/7276333b114b4fd690854ad31d4fd582

Sex-specific familial aggregation of cancers in Finland

Autor: Lauri J. Sipilä, Karri Seppä, Mervi Aavikko, Janne Ravantti, Sanna Heikkinen, Lauri A. Aaltonen, Janne Pitkäniemi

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)

Abstract Despite the fact that the effect of sex on the occurrence of cancers has been studied extensively, it remains unclear whether sex modifies familial aggregation of cancers. We explored sex-specific familial aggregation of cancers in a large p

Externí odkaz: https://doaj.org/article/51c791a5403c4ddbb3745d7567faf9a0

Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial

Autor: Melinda B Roaldsen, Agnethe Eltoft, Tom Wilsgaard, Hanne Christensen, Stefan T Engelter, Bent Indredavik, Dalius Jatužis, Guntis Karelis, Janika Kõrv, Erik Lundström, Jesper Petersson, Jukka Putaala, Mary-Helen Søyland, Arnstein Tveiten, Andrew Bivard, Stein Harald Johnsen, Michael V Mazya, David J Werring, Teddy Y Wu, Gian Marco De Marchis, Thompson G Robinson, Ellisiv B Mathiesen, M Parson, M Valente, A Chen, A Sharobeam, L Edwards, C Blair, L Christensen, K Ægidius, T Pihl, C Fassel-Larsen, L Wassvik, M Folke, S Rosenbaum, S S Gharehbagh, A Hansen, N Preisler, K Antsov, S Mallene, M Lill, M Herodes, R Vibo, A Rakitin, J Saarinen, M Tiainen, O Tumpula, T Noppari, S Raty, G Sibolt, J Nieminen, J Niederhauser, I Haritoncenko, J Puustinen, T-M Haula, J Sipilä, B Viesulaite, S Taroza, D Rastenyte, V Matijosaitis, A Vilionskis, R Masiliunas, A Ekkert, P Chmeliauskas, V Lukosaitis, A Reichenbach, T T Moss, H Y Nilsen, R Hammer-Berntzen, L M Nordby, T A Weiby, K Nordengen, H Ihle-Hansen, M Stankiewiecz, O Grotle, M Nes, K Thiemann, I M Særvold, M Fraas, S Størdahl, J W Horn, H Hildrum, C Myrstad, H Tobro, J-A Tunvold, O Jacobsen, N Aamodt, H Baisa, V N Malmberg, G Rohweder, H Ellekjær, F Ildstad, E Egstad, B H Helleberg, H H Berg, J Jørgensen, E Tronvik, M Shirzadi, R Solhoff, R Van Lessen, A Vatne, K Forselv, H Frøyshov, M S Fjeldstad, L Tangen, S Matapour, K Kindberg, C Johannessen, M Rist, I Mathisen, T Nyrnes, A Haavik, G Toverud, K Aakvik, M Larsson, K Ytrehus, S Ingebrigtsen, T Stokmo, C Helander, I C Larsen, T O Solberg, Y M Seljeseth, S Maini, I Bersås, J Mathé, E Rooth, A-C Laska, A-S Rudberg, M Esbjörnsson, F Andler, A Ericsson, O Wickberg, J-E Karlsson, P Redfors, K Jood, F Buchwald, K Mansson, O Gråhamn, K Sjölin, E Lindvall, Å Cidh, A Tolf, O Fasth, B Hedström, J Fladt, T D Dittrich, L Kriemler, N Hannon, E Amis, S Finlay, J Mitchell-Douglas, J McGee, R Davies, V Johnson, A Nair, M Robinson, J Greig, O Halse, P Wilding, S Mashate, K Chatterjee, M Martin, S Leason, J Roberts, D Dutta, D Ward, R Rayessa, E Clarkson, J Teo, C Ho, S Conway, M Aissa, V Papavasileiou, S Fry, D Waugh, J Britton, A Hassan, L Manning, S Khan, A Asaipillai, C Fornolles, M L Tate, S Chenna, T Anjum, D Karunatilake, J Foot, L VanPelt, A Shetty, G Wilkes, A Buck, B Jackson, L Fleming, M Carpenter, L Jackson, A Needle, T Zahoor, T Duraisami, K Northcott, J Kubie, A Bowring, S Keenan, D Mackle, T England, B Rushton, A Hedstrom, S Amlani, R Evans, G Muddegowda, A Remegoso, P Ferdinand, R Varquez, M Davis, E Elkin, R Seal, M Fawcett, C Gradwell, C Travers, B Atkinson, S Woodward, L Giraldo, J Byers, B Cheripelli, S Lee, R Marigold, S Smith, L Zhang, R Ghatala, C H Sim, U Ghani, K Yates, S Obarey, M Willmot, K Ahlquist, M Bates, K Rashed, S Board, G Andsberg, S Sundayi, M Garside, M-J Macleod, A Manoj, O Hopper, B Cederin, T Toomsoo, K Gross-Paju, T Tapiola, J Kestutis, K-F Amthor, B Heermann, V Ottesen, T A Melum, M Kurz, M Parsons

Publikováno v: The Lancet. Neurology.

Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often sca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77e948b8214830b257c18297ff5e11d
https://pubmed.ncbi.nlm.nih.gov/36549308

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WNT2 activation through proximal germline deletion predisposes to small intestinal neuroendocrine tumors and intestinal adenocarcinomas

Autor: Ilkka Heiskanen, Pekka Katajisto, Päivi Pihlajamaa, Pia Vahteristo, Camilla Schalin-Jäntti, Olli Carpén, Lauri A. Aaltonen, Noora Andersson, Lauri J. Sipilä, Jussi Taipale, Riku Katainen, Iikki Donner, Simona Bramante, Päivi Sulo, Nalle Pentinmikko, Kaisa Lehti, Anna Kuosmanen, Erika Gucciardo, Johanna Arola, Mervi Aavikko, Eevi Kaasinen, Jukka-Pekka Mecklin, Samantha Martin, Ari Ristimäki

Publikováno v: Human Molecular Genetics

Many hereditary cancer syndromes are associated with an increased risk of small and large intestinal adenocarcinomas. However, conditions bearing a high risk to both adenocarcinomas and neuroendocrine tumors are yet to be described. We studied a fami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5b0080e1acc11c147c2829754d8692
http://urn.fi/URN:NBN:fi:jyu-202202091457