Zobrazeno 1 - 10
of 77
pro vyhledávání: '"J. Simon Wiegert"'
Autor:
Johannes Oppermann, Paul Fischer, Arita Silapetere, Bernhard Liepe, Silvia Rodriguez-Rozada, José Flores-Uribe, Enrico Schiewer, Anke Keidel, Johannes Vierock, Joel Kaufmann, Matthias Broser, Meike Luck, Franz Bartl, Peter Hildebrandt, J. Simon Wiegert, Oded Béjà, Peter Hegemann, Jonas Wietek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/768a4007f7834da395853386ee5bf11d
Autor:
Amelie C. F. Bergs, Jana F. Liewald, Silvia Rodriguez-Rozada, Qiang Liu, Christin Wirt, Artur Bessel, Nadja Zeitzschel, Hilal Durmaz, Adrianna Nozownik, Holger Dill, Maëlle Jospin, Johannes Vierock, Cornelia I. Bargmann, Peter Hegemann, J. Simon Wiegert, Alexander Gottschalk
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Optogenetic actuation regimes are often static, which allows perturbation, but not true control of neuronal activity. Here, the authors describe an all-optical method for bidirectional steering of membrane potential, in closed loop, in C. elegans mus
Externí odkaz:
https://doaj.org/article/4373263f0a2a4c2cbd268fdc4a4ba5a6
Autor:
Martin Kubitschke, Monika Müller, Lutz Wallhorn, Mauro Pulin, Manuel Mittag, Stefan Pollok, Tim Ziebarth, Svenja Bremshey, Jill Gerdey, Kristin Carolin Claussen, Kim Renken, Juliana Groß, Pascal Gneiße, Niklas Meyer, J. Simon Wiegert, Andreas Reiner, Martin Fuhrmann, Olivia Andrea Masseck
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Genetically encoded sensors have been developed and become versatile tools for imaging serotonin dynamics. Here, authors developed a family of serotonin (5-HT) sensors (sDarken), three variants with different affinities for 5-HT enable high spatiotem
Externí odkaz:
https://doaj.org/article/67b7ba204f424e40b9234b7c93a4305b
Autor:
Céline D. Dürst, J. Simon Wiegert, Christian Schulze, Nordine Helassa, Katalin Török, Thomas G. Oertner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
It is not fully understood if the probability of synaptic vesicle release is homogenous or varies between individual boutons. Here the authors perform optical quantal analyses of individual Schaffer collateral synapses, showing that multivesicular re
Externí odkaz:
https://doaj.org/article/ec98135871a740eab353949d02d4d63f
Autor:
Silvia Rodriguez-Rozada, Jonas Wietek, Federico Tenedini, Kathrin Sauter, Neena Dhiman, Peter Hegemann, Peter Soba, J. Simon Wiegert
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Aion is an anion-conducting, bistable channelrhodopsin that enables long-term silencing of neuronal networks, as demonstrated in organotypic hippocampal cultures and Drosophila melanogaster larvae.
Externí odkaz:
https://doaj.org/article/22517d16d1e5465185854dba3c42e5e3
Autor:
Ahmed Wagdi, Daniela Malan, Udhayabhaskar Sathyanarayanan, Janosch S. Beauchamp, Markus Vogt, David Zipf, Thomas Beiert, Berivan Mansuroglu, Vanessa Dusend, Mark Meininghaus, Linn Schneider, Bernd Kalthof, J. Simon Wiegert, Gabriele M. König, Evi Kostenis, Robert Patejdl, Philipp Sasse, Tobias Bruegmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Gq proteins are one of four major classes of G proteins; optogenetic receptors for selective and repetitive activation of Gq proteins with fast kinetics are lacking. Here the authors report UV light-dependent Gq signalling using human Neuropsin (hOPN
Externí odkaz:
https://doaj.org/article/a279b477c4f4465bb0b225dabc9ba09a
Autor:
Andrey Formozov, Mattia Chini, Alexander Dieter, Wei Yang, Jastyn A. Pöpplau, Ileana L. Hanganu-Opatz, J. Simon Wiegert
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-11 (2022)
Measurement(s) brain activity measurement • pupil dilation Technology Type(s) two-photon calcium imaging • local field potential recording • videography Factor Type(s) calcium imaging data • local field potentials Sample Characteristic - Orga
Externí odkaz:
https://doaj.org/article/990868699b8d45bba39669662755a121
Autor:
Johannes Vierock, Silvia Rodriguez-Rozada, Alexander Dieter, Florian Pieper, Ruth Sims, Federico Tenedini, Amelie C. F. Bergs, Imane Bendifallah, Fangmin Zhou, Nadja Zeitzschel, Joachim Ahlbeck, Sandra Augustin, Kathrin Sauter, Eirini Papagiakoumou, Alexander Gottschalk, Peter Soba, Valentina Emiliani, Andreas K. Engel, Peter Hegemann, J. Simon Wiegert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Currently, bidirectional control of activity in the same neurons in the same experiment is difficult. Here the authors report a Bidirectional Pair of Opsins for Light-induced Excitation and Silencing, BiPOLES, which they use in a range of organisms i
Externí odkaz:
https://doaj.org/article/b02c3e09c1c84a398a03b09759bad1d1
Autor:
Alberto Perez-Alvarez, Brenna C. Fearey, Ryan J. O’Toole, Wei Yang, Ignacio Arganda-Carreras, Paul J. Lamothe-Molina, Benjamien Moeyaert, Manuel A. Mohr, Lauren C. Panzera, Christian Schulze, Eric R. Schreiter, J. Simon Wiegert, Christine E. Gee, Michael B. Hoppa, Thomas G. Oertner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Calcium imaging has been used to visualize the activity of individual synapses, but cannot be scaled up to monitor thousands of synapses in tissue. Here, the authors present genetic tools that can be photoconverted from green to red to create a map o
Externí odkaz:
https://doaj.org/article/7d7a281a0ac548d19a0654bd5702913e
Autor:
Ahmed Wagdi, Daniela Malan, Udhayabhaskar Sathyanarayanan, Janosch S. Beauchamp, Markus Vogt, David Zipf, Thomas Beiert, Berivan Mansuroglu, Vanessa Dusend, Mark Meininghaus, Linn Schneider, Bernd Kalthof, J. Simon Wiegert, Gabriele M. König, Evi Kostenis, Robert Patejdl, Philipp Sasse, Tobias Bruegmann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/8eaba225fb6a43418e646ee10581c265