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Akademický článek

STAS Domain Only Proteins in Bacterial Gene Regulation

Autor: Brian E. Moy, J. Seshu

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Sulfate Transport Anti-Sigma antagonist domains (Pfam01740) are found in all branches of life, from eubacteria to mammals, as a conserved fold encoded by highly divergent amino acid sequences. These domains are present as part of larger SLC26/SulP an

Externí odkaz: https://doaj.org/article/1132188c86984813ae50345ea4b33ee3

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Akademický článek

Acinetobacter baumannii Gastrointestinal Colonization Is Facilitated by Secretory IgA Which Is Reductively Dissociated by Bacterial Thioredoxin A

Autor: Patrick M. Ketter, Jieh-Juen Yu, M. Neal Guentzel, Holly C. May, Rishein Gupta, Mark Eppinger, Karl E. Klose, J. Seshu, James P. Chambers, Andrew P. Cap, Bernard P. Arulanandam

Publikováno v: mBio, Vol 9, Iss 4 (2018)

ABSTRACT Multidrug-resistant Acinetobacter baumannii is among the most common causes of infectious complications associated with combat-related trauma in military personnel serving overseas. However, little is currently known about its pathogenesis.

Externí odkaz: https://doaj.org/article/7480d67b7fd14314a565b9db129cb4d8

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Akademický článek

Absence of sodA Increases the Levels of Oxidation of Key Metabolic Determinants of Borrelia burgdorferi.

Autor: Maria D Esteve-Gassent, Trever C Smith, Christina M Small, Derek P Thomas, J Seshu

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0136707 (2015)

Borrelia burgdorferi, the causative agent of Lyme disease, alters its gene expression in response to environmental signals unique to its tick vector or vertebrate hosts. B. burgdorferi carries one superoxide dismutase gene (sodA) capable of controlli

Externí odkaz: https://doaj.org/article/df9aafc9cbaa48389e176bb558588322

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Akademický článek

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Akademický článek

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Elektronická kniha

Monoclonal Antibodies Application In Disease And Health

Autor: G. Dhinakar Raj, J. Seshu

India is likely to become a major force in the area of Biotechnology in the next decade. The Department of Biotechnology has encouraged human resource development by creating new institutions and centres of excellence for the research and training. A

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Synthesis in Escherichia coli of two smaller enzymically active analogues of Coxiella burnetii macrophage infectivity potentiator (CbMip) protein utilizing a single open reading frame from the cbmip gene

Autor: Louis P. Mallavia, Yin-Yuan Mo, Dong Wang, J. Seshu

Publikováno v: Biochemical Journal. 335:67-77

FK506-binding proteins (FKBPs) have been identified in a variety of eukaryotic and prokaryotic organisms. Macrophage infectivity potentiator (CbMip, 23.5 kDa) protein of the obligate intracellular bacterium, Coxiella burnetii, was shown previously to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa35cfc1f94f44b4ee688ed44908821
https://doi.org/10.1042/bj3350067

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Borrelia host adaptation Regulator (BadR) regulates rpoS to modulate host adaptation and virulence factors in Borrelia burgdorferi

Autor: Christine L, Miller, S L Rajasekhar, Karna, J, Seshu

Publikováno v: Molecular microbiology. 88(1)

The RpoS transcription factor of Borrelia burgdorferi is a 'gatekeeper' because it activates genes required for spirochaetes to transition from tick to vertebrate hosts. However, it remains unknown how RpoS becomes repressed to allow the spirochaetes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf16ef39f39a2d841aadd6955ab81238
https://pubmed.ncbi.nlm.nih.gov/23387366

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Inactivation of the fibronectin-binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi

Autor: J, Seshu, M Dolores, Esteve-Gassent, Maria, Labandeira-Rey, Jung Hwa, Kim, Jerome P, Trzeciakowski, Magnus, Höök, Jonathan T, Skare

Publikováno v: Molecular microbiology. 59(5)

Borrelia burgdorferi, the aetiological agent of Lyme disease, utilizes multiple adhesins to interact with both the arthropod vector and mammalian hosts it colonizes. One such adhesive molecule is a surface-exposed fibronectin-binding lipoprotein, des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1b3a68dcd5170a391e86808b164f6518
https://pubmed.ncbi.nlm.nih.gov/16468997

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A conservative amino acid change alters the function of BosR, the redox regulator of Borrelia burgdorferi

Autor: J, Seshu, Julie A, Boylan, Jenny A, Hyde, Kristen L, Swingle, Frank C, Gherardini, Jonathan T, Skare

Publikováno v: Molecular microbiology. 54(5)

Borrelia burgdorferi, the aetiologic agent of Lyme disease, modulates gene expression in response to changes imposed by its arthropod vector and mammalian hosts. As reactive oxygen species (ROS) are known to vary in these environments, we asked how B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6156aba7e378973b3f113094bb10eb3c
https://pubmed.ncbi.nlm.nih.gov/15554974

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