Zobrazeno 1 - 10
of 19
pro vyhledávání: '"J. Scott Hayes"'
Autor:
J. Scott Hayes, David W. Robertson
Publikováno v:
Cardiovascular Drug Reviews. 5:189-215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0128211a73d64bc7ab857fa9d0a259e3
https://doi.org/10.1111/j.1527-3466.1987.tb00509.x
https://doi.org/10.1111/j.1527-3466.1987.tb00509.x
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 36:1199-1203
[ 3 H]RU38486 (RU486) was synthesized from its penultimate precursor, desmethyl RU486, by substitution of the secondary amine with tritiated methyl iodide ; specific activity 85 Ci/mmol. Ligand binding studies confirm that RU486 binds with high affin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5f637674be1caa7fd4ef1c417fcff3
https://doi.org/10.1002/jlcr.2580361210
https://doi.org/10.1002/jlcr.2580361210
Publikováno v:
Journal of Cardiovascular Pharmacology. 20:742-749
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4dda4a88491728695e11803bac40f8
https://doi.org/10.1097/00005344-199211000-00009
https://doi.org/10.1097/00005344-199211000-00009
Autor:
Federico Dies, Ronald B. Franklin, John McNay, Raymond F. Kauffman, J. Scott Hayes, George E. Sandusky, David W. Robertson
Publikováno v:
Cardiovascular Drug Reviews. 8:303-322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7de45d49a167cd67c9b01271dd6c9ee6
https://doi.org/10.1111/j.1527-3466.1990.tb00398.x
https://doi.org/10.1111/j.1527-3466.1990.tb00398.x
Autor:
Raymond F. Kauffman, Virginia L. Wyss, Barbara G. Utterback, J. Scott Hayes, Peter J. Gengo, Nancy Bowling
Publikováno v:
European journal of pharmacology. 187(2)
Effects of prolonged isoproterenol infusion upon the density of cardiac calcium channels, calcium-mediated contractile responses, and the ability of forskolin to enhance tension development and cyclic AMP accumulation were studied in ventricular musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28813f46526a9c8173977e89d6cf4912
https://pubmed.ncbi.nlm.nih.gov/1703077
https://pubmed.ncbi.nlm.nih.gov/1703077
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 812:313-320
Isoproterenol increased contractility in isolated cat papillary muscles 2-fold with an EC 50 of 6.3·10 -8 M. Nifedipine (3·10 -7 M) reduced contractility in control muscles by 43%; however, inotropic state was restored by isoproterenol with a compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aae6f6a06d3fa4a2260c3e88cc9ebb2
https://doi.org/10.1016/0005-2736(85)90305-0
https://doi.org/10.1016/0005-2736(85)90305-0
Publikováno v:
Life Sciences. 31:2519-2527
The effects of insulin and glucagon on CAMP accumulation, protein kinase activation, and glycogenolysis were investigated in isolated rat hepatocytes. Glucagon (0.01 nM to 10 μM) increased the activation state of protein kinase and the rate of gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d300a08e1112ae83e60ee35b298bb6
https://doi.org/10.1016/0024-3205(82)90759-7
https://doi.org/10.1016/0024-3205(82)90759-7
Publikováno v:
Proceedings of the National Academy of Sciences. 76:1570-1574
The relationship between the effects of isoproterenol and prostaglandin E 1 (PGE 1 ) on contractile state, cyclic AMP accumulation, and the activation states of protein kinase (ATP: protein phosphotransferase, EC 2.7.1.37), phosphorylase kinase, glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883fa0f6e7ece6f87605ab687dc580b1
https://doi.org/10.1073/pnas.76.4.1570
https://doi.org/10.1073/pnas.76.4.1570
Publikováno v:
Nature. 280:78-80
WE recently reported that PGE1 and isoprenaline have very different effects on the substrates of cyclic AMP-dependent protein kinase that regulate cardiac glycogen metabolism. Both agents elevated the cyclic" AMP content and the protein kinase activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ce918175836be693589b711971b164
https://doi.org/10.1038/280078a0
https://doi.org/10.1038/280078a0
