Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J. Scott Gens"'
Autor:
Abbas Shirinifard, James Alexander Glazier, Maciej Swat, J Scott Gens, Fereydoon Family, Yi Jiang, Hans E Grossniklaus
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 5, p e1002440 (2012)
Choroidal neovascularization (CNV) of the macular area of the retina is the major cause of severe vision loss in adults. In CNV, after choriocapillaries initially penetrate Bruch's membrane (BrM), invading vessels may regress or expand (CNV initiatio
Externí odkaz:
https://doaj.org/article/7aec8a87954f41b3b0c14dd03743282c
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 10, p e1002155 (2011)
Somitogenesis, the formation of the body's primary segmental structure common to all vertebrate development, requires coordination between biological mechanisms at several scales. Explaining how these mechanisms interact across scales and how events
Externí odkaz:
https://doaj.org/article/014786f8c2ae4847a0fbc120ee84120d
Autor:
Nikodem J Poplawski, Abbas Shirinifard, Ubirajara Agero, J Scott Gens, Maciej Swat, James A Glazier
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10641 (2010)
We use the Glazier-Graner-Hogeweg model to simulate three-dimensional (3D), single-phenotype, avascular tumors growing in an homogeneous tissue matrix (TM) supplying a single limiting nutrient. We study the effects of two parameters on tumor morpholo
Externí odkaz:
https://doaj.org/article/3bb657c5e84b4a49bd1247d8db9f10c5
Autor:
Abbas Shirinifard, J Scott Gens, Benjamin L Zaitlen, Nikodem J Popławski, Maciej Swat, James A Glazier
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7190 (2009)
We present a 3D multi-cell simulation of a generic simplification of vascular tumor growth which can be easily extended and adapted to describe more specific vascular tumor types and host tissues. Initially, tumor cells proliferate as they take up th
Externí odkaz:
https://doaj.org/article/8a0b88616fc840fea6ac27cfdf8f80ae
Autor:
Nikodem J. Popławski, Ubirajara Agero, J. Scott Gens, Maciej Swat, James A. Glazier, Alexander R. A. Anderson
Publikováno v:
Bulletin of Mathematical Biology. 71:1189-1227
We study the interface morphology of a 2D simulation of an avascular tumor composed of identical cells growing in an homogeneous healthy tissue matrix (TM), in order to understand the origin of the morphological changes often observed during real tum
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1768(5):1023-1035
We tested whether NHE3 and NHE2 Na(+)/H(+) exchanger isoforms were recruited to the plasma membrane (PM) in response to changes in ion homeostasis. NHE2-CFP or NHE3-CFP fusion proteins were functional Na(+)/H(+) exchangers when transiently expressed
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1712(1):71-80
MDCK cells stably transfected with betaine/GABA transporter tagged with EGFP (EGFP-BGT) were used to study plasma membrane insertion of EGFP-BGT. Adaptive response to hypertonicity requires nuclear migration of TonEBP. Confocal microscopy showed that
Publikováno v:
Plant Physiology. 119:1165-1176
A unique subfamily of calmodulin-dependent Ca2+-ATPases was recently identified in plants. In contrast to the most closely related pumps in animals, plasma membrane-type Ca2+-ATPases, members of this new subfamily are distinguished by a calmodulin-re
Publikováno v:
The FASEB Journal. 27
Publikováno v:
The Plant Journal. 7:273-286
In Arabidopsis thaliana ribosomal RNA genes (rRNA genes or rDNA) are grouped in two nucleolus organizer regions(NORs) that together comprise approximately 6% of the genome. The map positions of the NORs relative to other genetic markers are unknown.