Zobrazeno 1 - 10
of 185
pro vyhledávání: '"J. Schmeisser"'
Autor:
Tommaso Zeppillo, Heba Ali, Sowbarnika Ravichandran, Tamara C. Ritter, Sally Wenger, Francisco J. López-Murcia, Erinn Gideons, Janetti Signorelli, Michael J. Schmeisser, Jens Wiltfang, JeongSeop Rhee, Nils Brose, Holger Taschenberger, Dilja Krueger-Burg
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Neuroligin-2 (Nlgn2) is a key synaptic adhesion protein at virtually all GABAergic synapses, which recruits GABAARs by promoting assembly of the postsynaptic gephyrin scaffold. Intriguingly, loss of Nlgn2 differentially affects subsets of GA
Externí odkaz:
https://doaj.org/article/41e5aaf4d91e4e0cb3c838533f2777d1
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 5, Pp 1236-1243 (2025)
The N-terminal EF-hand calcium-binding proteins 1–3 (NECAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one EF-hand calcium-binding domain and a functionally less well characterized C-termin
Externí odkaz:
https://doaj.org/article/86cd6c606f324f18a33befe8fb30a11d
Autor:
Ernestine Saumweber, Slim Mzoughi, Arin Khadra, Anja Werberger, Sven Schumann, Ernesto Guccione, Michael J. Schmeisser, Susanne J. Kühl
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Mutations in PRDM15 lead to a syndromic form of holoprosencephaly (HPE) known as the Galloway–Mowat syndrome (GAMOS). While a connection between PRDM15, a zinc finger transcription factor, and WNT/PCP signaling has been established, there is a crit
Externí odkaz:
https://doaj.org/article/78d2540a478644248a459c33f482b656
Autor:
Leonardo Nardi, Stuti Chhabra, Petra Leukel, Dilja Krueger-Burg, Clemens J. Sommer, Michael J. Schmeisser
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Autism spectrum disorder (ASD) comprises a wide range of neurodevelopment conditions primarily characterized by impaired social interaction and repetitive behavior, accompanied by a variable degree of neuropsychiatric characteristics. Synaptic dysfun
Externí odkaz:
https://doaj.org/article/7680e4f4e1dd46dc9718966c5422e354
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
The proper preservation of human brain tissue is an indispensable requirement for post-mortem investigations. Neuroanatomical teaching, neuropathological examination, neurosurgical training, basic and clinical neuroscientific research are some of the
Externí odkaz:
https://doaj.org/article/c1c2dcd8a8db443b864c61ef5d3bd667
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
As a chronic autoimmune disease systemic lupus erythematosus (SLE) can also affect the central and the peripheral nervous system causing symptoms which are summed up as neuropsychiatric systemic lupus erythematosus (NPSLE). These symptoms are heterog
Externí odkaz:
https://doaj.org/article/7f32c96521b54681b62608ad013b1285
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Autism spectrum disorder (ASD) comprises a wide range of neurodevelopmental phenotypes united by impaired social interaction and repetitive behavior. Environmental and genetic factors are associated with the pathogenesis of ASD, while other cases are
Externí odkaz:
https://doaj.org/article/524ba270f5664be09edb6eb08b9b4cc0
Autor:
Eduardo Rosales Jubal, Miriam Schwalm, Malena dos Santos Guilherme, Florian Schuck, Sven Reinhardt, Amanda Tose, Zeke Barger, Mona K. Roesler, Nicolas Ruffini, Anna Wierczeiko, Michael J. Schmeisser, Ulrich Schmitt, Kristina Endres, Albrecht Stroh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Aberrant activity of local functional networks underlies memory and cognition deficits in Alzheimer’s disease (AD). Hyperactivity was observed in microcircuits of mice AD-models showing plaques, and also recently in early stage AD mutants
Externí odkaz:
https://doaj.org/article/5f4ceae1b11d437c87d1b329fa7fb0a8
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
A synaptic sexual dimorphism is relevant in the context of multiple neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. Many of these disorders show a different prevalence and progression in woman and man. A similar variance is als
Externí odkaz:
https://doaj.org/article/2ecbff62167d46e495c3d129fd05efe9
Autor:
Katie Frenis, Sanela Kalinovic, Benjamin P. Ernst, Miroslava Kvandova, Ahmad Al Zuabi, Marin Kuntic, Matthias Oelze, Paul Stamm, Maria Teresa Bayo Jimenez, Agnieszka Kij, Karin Keppeler, Veronique Klein, Lea Strohm, Henning Ubbens, Steffen Daub, Omar Hahad, Swenja Kröller-Schön, Michael J. Schmeisser, Stefan Chlopicki, Jonas Eckrich, Sebastian Strieth, Andreas Daiber, Sebastian Steven, Thomas Münzel
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2022)
Transportation noise is recognized as an important cardiovascular risk factor. Key mechanisms are noise-triggered vascular inflammation and oxidative stress with subsequent endothelial dysfunction. Here, we test for adaptation or tolerance mechanisms
Externí odkaz:
https://doaj.org/article/4f079d332b40404090ea15ab5ec4c47f