Zobrazeno 1 - 10 of 115 pro vyhledávání: '"J. Sastre Toraño"'
1
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3
A validated HPLC assay to monitor riluzole plasma or serum concentrations in patients with amyotrophic lateral sclerosis
Autor: H. J. M. van Kan, L. H. van den Berg, Henk-Jan Guchelaar, M. Spieksma, Geert Jan Groeneveld, J. Sastre Toraño
Publikováno v: Biomedical Chromatography. 18:723-726
A specific, accurate and precise high-performance liquid chromatographic assay was developed for the determination of riluzole, a drug used to treat patients with amyotrophic lateral sclerosis. Samples were treated by extraction with dichloromethane
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f30294f342d0c74d91c3a6db950d9fc
https://doi.org/10.1002/bmc.384
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4
High-performance liquid chromatographic method with ultraviolet detection for the determination of dapsone and its hydroxylated metabolite in human plasma
Autor: S. Kwadijk, J. Sastre Toraño
Publikováno v: Biomedical Chromatography. 16:203-208
A validated high-performance liquid chromatographic method with ultraviolet detection for the quantitative determination of dapsone (4,4'-diaminodifenyl sulfone, DDS) and a metabolite, hydroxylaminodapsone (4-amino-4-hydroxylaminodiphenyl sulfone, DD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f228265775d13c303c2e04230517fdd
https://doi.org/10.1002/bmc.132
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5
Akademický článek
Recent Advances in Labeling-Based Quantitative Glycomics: From High-Throughput Quantification to Structural Elucidation.
Autor: Wang Z; School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA., Zhang J; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA., Li L; School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Lachman Institute for Pharmaceutical Development, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Wisconsin Center for NanoBioSystems, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Publikováno v: Proteomics [Proteomics] 2024 Nov 24, pp. e202400057. Date of Electronic Publication: 2024 Nov 24.
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6
Inter- and intraindividual variability of riluzole serum concentrations in patients with ALS
Autor: Henk-Jan Guchelaar, Geert Jan Groeneveld, L.H. van den Berg, H. J. M. van Kan, Jan H. Veldink, J. Sastre Toraño, John H. J. Wokke
Publikováno v: Journal of the Neurological Sciences. 191:121-125
All patients with amyotrophic lateral sclerosis (ALS) are treated with the same dose of riluzole: 50 mg twice daily. Reasonably large interindividual differences in clearance of the drug have been reported. The relatively small group of patients with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119b9879bcb3d40d36aca387b5573a18
https://doi.org/10.1016/s0022-510x(01)00613-x
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7
Simultaneous determination of flucytosine and fluorouracil in human plasma by high-performance liquid chromatography
Autor: J. Sastre Toraño, Henk-Jan Guchelaar, A. Vermes
Publikováno v: Biomedical Chromatography. 15:89-94
A validated, sensitive and precise reversed-phase high-performance liquid chromatographic method for the simultaneous determination of 5-flucytosine (5-FC) and 5-fluorouracil (5-FU) in human plasma is described. Two compounds, 5-methylcytosine (5-MC)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ae0ec0e10f859450a9b52e3f1e7ab6b
https://doi.org/10.1002/bmc.38
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8
Recent developments in capillary isoelectric focusing
Autor: Linda H. H. Silvertand, G.J. de Jong, W.P. van Bennekom, J. Sastre Toraño
Publikováno v: Journal of chromatography. A. 1204(2)
The developments in capillary isoelectric focusing (cIEF) over the period 2003-2007 are reviewed. With the focus on technological aspects, cIEF papers published in the fields of methodology, new techniques, detection, multidimensional systems, miniat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499c61ad8bc9ef07d02c6585148972ad
https://pubmed.ncbi.nlm.nih.gov/18565533
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9
Nasal drug delivery to the cerebrospinal fluid: transport of a lipophilic compound
Autor: Frans W. H. M. Merkus, Henk-Jan Guchelaar, J. Sastre Toraño, P C Van Rijn-Bikker, Paul Merkus, D A Bosch
The aim of this study was to investigate the possibility of direct transport of drugs from the olfactory area to the cerebrospinal fluid (CSF) by intranasal administration (i.n.) of a lipophilic drug in human volunteers. In a large number of animal s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7856495c0e21f9428f09bc27d3c964c3
https://europepmc.org/articles/PMC1874457/
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10
Quantitative analysis of active compounds in pharmaceutical preparations by use of attenuated total-reflection Fourier transform mid-infrared spectrophotometry and the internal standard method
Autor: J. Sastre Toraño, S. Hattum
Publikováno v: Fresenius' journal of analytical chemistry. 371(4)
A new method is presented for the quantitative analysis of compounds in pharmaceutical preparations Fourier transform (FT) mid-infrared (MIR) spectroscopy with an attenuated total reflection (ATR) module. Reduction of the quantity of overlapping abso
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3316ac7c82b0f188c1fd4ad86ed20006
https://pubmed.ncbi.nlm.nih.gov/11760065
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