Výsledky vyhledávání - "J. S. Wolinsky"

The relationship of MS to physical trauma and psychological stress: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

Autor: M. Rodriguez, George C. Ebers, J. S. Wolinsky, W. A. Sibley, K. P. Johnson, Douglas S. Goodin

Publikováno v: Scopus-Elsevier

Overview. The idea that physical trauma or psychological stress might be involved in either the causation or exacerbation of MS dates back to the time of Charcot and the earliest descriptions of the illness.1 In 1897, for example, Mendel reported fou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9319925977077ae76d373ffe0e2877
https://doi.org/10.1212/wnl.52.9.1737

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The PROMiSe trial: baseline data review and progress report

Autor: J. S Wolinsky, null PROMiSe Trial Study Group

Publikováno v: Multiple Sclerosis. 10:S65-S72

The PROMiSe trial is a multinational, multicentre, double-blind, placebo-controlled trial evaluating the effects of glatiramer acetate treatment over 3 years in patients with primary progressive multiple sclerosis (PPMS). A total of 943 patients were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf66136a790fc96ccf4e21c967edefa
https://doi.org/10.1177/135245850401000112

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Linomide in relapsing and secondary progressive MS: Part I: Trial design and clinical results

Autor: H. C. Sullivan, J. S. Wolinsky, John H. Noseworthy, P. Gjorstrup, Fred D. Lublin, A. Linde, J. N. Whitaker

Publikováno v: Neurology. 54:1726-1733

Objective: To determine whether linomide (roquinimex) is better than placebo in slowing the time to confirmed clinical worsening in patients with relapsing–remitting (RR) and secondary progressive (SP) MS. Methods: In this 27-center, randomized, do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b71cbb8a5ceaa20c83ef46f20c486144
https://doi.org/10.1212/wnl.54.9.1726

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H reflex studies in cerebral palsy patients undergoing partial dorsal rhizotomy

Autor: R M Scott, Eric L. Logigian, Joseph R. Madsen, J S Wolinsky, Sulpicio G. Soriano

Publikováno v: Muscle & Nerve. 17:539-549

H reflex studies were performed in ten spastic children with cerebral palsy who underwent partial dorsal rhizotomy (PDR). Under anesthesia prior to PDR, H reflex amplitude evoked by percutaneous peripheral nerve stimulation gradually declined in all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::485ca6b224072d0df1e62ac7ec2ec232
https://doi.org/10.1002/mus.880170512

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Monoclonal antibody to rubella virus capsid protein recognizes a beta-cell antigen

Autor: D G Karounos, J S Wolinsky, J W Thomas

Publikováno v: The Journal of Immunology. 150:3080-3085

The high frequency of insulin-dependent diabetes (IDDM) in children with congenital rubella suggests that the infectious agent may trigger the autoimmune process. To explore the immunologic relationship between rubella virus and IDDM, we examined a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09b405497ad5b37ab401c3a69a28de76
https://doi.org/10.4049/jimmunol.150.7.3080

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Pathophysiology of multiple sclerosis and the place of teriflunomide

Autor: R, Gold, J S, Wolinsky

Publikováno v: Acta neurologica Scandinavica. 124(2)

Significant progress in multiple sclerosis (MS) treatment has been made over the last two decades, including the emergence of disease-modifying therapy (DMT). However, substantial unmet medical need persists and has stimulated the search for new ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9a90db14eb997e4bf4c7c77d47bb93a6
https://pubmed.ncbi.nlm.nih.gov/20880295

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Survival, and time to an advanced disease state or progression, of untreated patients with moderately severe multiple sclerosis in a multicenter observational database: relevance for design of a clinical trial for high dose immunosuppressive therapy with autologous hematopoietic stem cell transplantation

Autor: M, Daumer, L M, Griffith, W, Meister, R A, Nash, J S, Wolinsky

Publikováno v: Multiple sclerosis (Houndmills, Basingstoke, England). 12(2)

Despite prolonged survival, patients with multiple sclerosis (MS) experience considerable morbidity, which adversely impacts quality of life. To assess the risk-benefit of a clinical trial of high dose immunosuppressive therapy with autologous hemato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::647d041926c5910099b08a41107474cc
https://pubmed.ncbi.nlm.nih.gov/16629420

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