Zobrazeno 1 - 10
of 12
pro vyhledávání: '"J. S. Wold"'
Publikováno v:
Journal of Infectious Diseases. 137:S17-S24
The hydrolysis of cefamandole nafate, and the O-formyl ester of cefamandole, to cefamandole was studied in vivo in dogs and normal human subjects. After administration of cefamandole nafate to dogs or humans, the parent compound disappeared rapidly f
Publikováno v:
Journal of Infectious Diseases. 137:S51-S59
The safety of cefamandole nafate in laboratory animals was evaluated in six species. The acute toxicity of cefamandole after intravenous or subcutaneous administration was similar to that of cephalothin sodium. The subacute and chronic toxicity of ce
Autor:
J. S. Wold
Publikováno v:
American Journal of Science. 240:617-626
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 3(1)
Radioactivity was excreted in the urine and feces of rats, mice, and humans after a dose of 14C-cyproheptadine. The major metabolite in rat urine was unconjugated, but the majority of radioactive materials in mouse and human urine were conjugated wit
Autor:
J S, Wold, S A, Turnipseed
Publikováno v:
Life sciences. 27(25-26)
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 201(3)
The nephrotoxicity of cephaloridine, cefazolin and mercuric chloride was studied in rabbits of various ages. Cephaloridine produced dose-related elevations in serum urea nitrogen, creatinine and renal tubular necrosis in adult and 30-day-old rabbits,
Autor:
J S, Wold, S A, Turnipseed
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 6(1)
The accumulation of cephaloridine in the renal cortex of the rabbit was studied in vitro and in vivo in rabbits of various ages. The cortical concentration of cephaloridine, the cortex/serum ratio, and the slice/medium ratio determined by incubation
Publikováno v:
JAMA. 245(20)
Autor:
J S, Wold, S A, Turnipseed
Publikováno v:
Reviews of infectious diseases.
The 50% lethal dose (LD50) of vancomycin for rodents was higher than that of tobramycin but much lower than that of cefamandole nafate. The rodents died in clonic convulsions immediately after receiving vancomycin. The LD50 for dogs similar to that f
Autor:
J S, Wold, W J, Steele
Publikováno v:
Molecular pharmacology. 8(6)