Zobrazeno 1 - 10
of 12
pro vyhledávání: '"J. S. Trimmer"'
Autor:
D J, Speca, G, Ogata, D, Mandikian, H I, Bishop, S W, Wiler, K, Eum, H Jürgen, Wenzel, E T, Doisy, L, Matt, K L, Campi, M S, Golub, J M, Nerbonne, J W, Hell, B C, Trainor, J T, Sack, P A, Schwartzkroin, J S, Trimmer
Publikováno v:
Genes, brain, and behavior. 13(4)
The Kv2.1 delayed rectifier potassium channel exhibits high-level expression in both principal and inhibitory neurons throughout the central nervous system, including prominent expression in hippocampal neurons. Studies of in vitro preparations sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d10b5dd074baf6b538290935d57d20ef
https://pubmed.ncbi.nlm.nih.gov/24494598
https://pubmed.ncbi.nlm.nih.gov/24494598
Autor:
M N, Rasband, J S, Trimmer
Publikováno v:
The Journal of comparative neurology. 429(1)
Axonal K+ channels involved in normal spinal cord function are candidate targets for therapeutics, which improve sensorimotor function in spinal cord injury. To this end, we have investigated the expression, localization, and coassociation of Kv1 alp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65e4f70eb16875a08cea53398b073ed5
https://pubmed.ncbi.nlm.nih.gov/11086297
https://pubmed.ncbi.nlm.nih.gov/11086297
Publikováno v:
Journal of neurocytology. 28(4-5)
The localization of Shaker-type K(+) channels in specialized domains of myelinated central nervous system axons was studied during development of the optic nerve. In adult rats Kv1.1, Kv1.2, Kv1.6, and the cytoplasmic beta-subunit Kvbeta2 were coloca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::436b7196117737519640529223269724
https://pubmed.ncbi.nlm.nih.gov/10739574
https://pubmed.ncbi.nlm.nih.gov/10739574
Publikováno v:
The Journal of comparative neurology. 412(2)
Here we investigate differences in the temporal and spatial patterning, and subunit interactions of two of the major Na(+) channel alpha-subunit isoforms in mammalian brain, the type I and type II Na(+) channels. By using subtype-specific antibodies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e3bcc0edf0463866be70ef5f29b44ff
https://pubmed.ncbi.nlm.nih.gov/10441760
https://pubmed.ncbi.nlm.nih.gov/10441760
Publikováno v:
Journal of molecular neuroscience : MN. 11(3)
To define the molecular characteristics of K+ channel beta-subunit polypeptides, we have studied their biochemical properties and subcellular distribution in transfected mammalian cells. We find that the recombinant voltage-dependent K+ (Kv) beta1.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61bf6f40a2e2adaa26e92e0c4785607d
https://pubmed.ncbi.nlm.nih.gov/10344790
https://pubmed.ncbi.nlm.nih.gov/10344790
Autor:
J S, Trimmer
Publikováno v:
Methods in enzymology. 293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49ba0e7bbe455d76924c9482d9c06984
https://pubmed.ncbi.nlm.nih.gov/9711601
https://pubmed.ncbi.nlm.nih.gov/9711601
Autor:
K J, Rhodes, M M, Monaghan, N X, Barrezueta, S, Nawoschik, Z, Bekele-Arcuri, M F, Matos, K, Nakahira, L E, Schechter, J S, Trimmer
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 16(16)
Recent cloning of K+ channel beta subunits revealed that these cytoplasmic polypeptides can dramatically alter the kinetics of current inactivation and promote efficient glycosylation and surface expression of the channel-forming alpha subunits. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95febc3511dc57ae68d16ea3b862f7da
https://pubmed.ncbi.nlm.nih.gov/8756417
https://pubmed.ncbi.nlm.nih.gov/8756417
Publikováno v:
The Journal of biological chemistry. 269(37)
We have transiently expressed the rat Kv2.1 K+ channel polypeptide (pKv2.1) at high levels by transfection of mammalian COS-1 cells. Kv2.1-transfected cells express a molecular mass of 108 kDa pKv2.1, larger than the size of the core polypeptide (95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e848773c22cccc4739fdf478e7e3460
https://pubmed.ncbi.nlm.nih.gov/8083226
https://pubmed.ncbi.nlm.nih.gov/8083226
Paramyotonia congenita and hyperkalemic periodic paralysis map to the same sodium-channel gene locus
Publikováno v:
American journal of human genetics. 49(4)
Paramyotonia congenita (PC), an autosomal dominant muscle disease, shares some clinical and electrophysiological similarities with another myotonic muscle disorder, hyperkalemic periodic paralysis (HYPP). However, clinical and electrophysiologic diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1e2a88dd859f2aea0a361832e6805af
https://pubmed.ncbi.nlm.nih.gov/1654742
https://pubmed.ncbi.nlm.nih.gov/1654742
Publikováno v:
Journal of Neurochemistry. 81:68-68
The node of Ranvier is composed of a complex community of axonal and glial proteins responsible for the propagation of electrical signals in myelinated nerve fibers. Both voltage-dependent sodium and potassium channels are found in high densities in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed05238d2d206527fcc1d927ffb8ec82
https://doi.org/10.1046/j.1471-4159.81.s1.97.x
https://doi.org/10.1046/j.1471-4159.81.s1.97.x