Zobrazeno 1 - 6
of 6
pro vyhledávání: '"J. S. Southerton"'
Autor:
J. Longmore, B. S. Brown, Susan Duty, D. T. Newgreen, P. B. Kay, A. D. McHarg, Arthur H. Weston, K.M. Bray, Gillian Edwards, J. S. Southerton
Publikováno v:
British Journal of Pharmacology. 100:605-613
1. The actions of diazoxide and minoxidil sulphate have been compared with those of cromakalim in rat aorta and portal vein. 2. Diazoxide and minoxidil sulphate hyperpolarized the rat portal vein in a similar manner to cromakalim. 3. Cromakalim, diaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a34565963a467df9000147a4c93971
https://doi.org/10.1111/j.1476-5381.1990.tb15854.x
https://doi.org/10.1111/j.1476-5381.1990.tb15854.x
Autor:
Roger C. Small, Sheila W. Weir, Arthur H. Weston, K.M. Bray, S.G. Taylor, D. T. Newgreen, J. S. Southerton
Publikováno v:
British Journal of Pharmacology. 91:421-429
The effects of pinacidil have been compared with those of glyceryl trinitrate (GTN) using the aorta and portal vein of the rat and the trachealis and taenia caeci of the guinea-pig. In aorta, both pinacidil and GTN inhibited responses to noradrenalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56225edc1f4acdf2557b4ae8db781a1f
https://doi.org/10.1111/j.1476-5381.1987.tb10297.x
https://doi.org/10.1111/j.1476-5381.1987.tb10297.x
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 338(3)
In rat aorta and rat portal vein, (-)- and (+)-pinacidil each produced a concentration-dependent inhibition of tension development. Although the (-) isomer was the more potent, concentration effect curves for each isomer were steep with similar slope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85dda042f2121989558f7ba0f79e5d1
https://pubmed.ncbi.nlm.nih.gov/2848206
https://pubmed.ncbi.nlm.nih.gov/2848206
Publikováno v:
Journal of cardiovascular pharmacology. 12
In rat portal vein and aorta, pinacidil (0.3-100 microM) inhibited spontaneous mechanical activity (portal vein) and responses to norepinephrine (0.001-100 microM) and to KCl (5-80 mM). Pinacidil and its analogs P1060 and P1368 inhibited established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c8b29ba5f45d0c5b4f1ed30f9e4e64
https://pubmed.ncbi.nlm.nih.gov/2466174
https://pubmed.ncbi.nlm.nih.gov/2466174
1. The mechanisms involved in the mechano-inhibitory effects of acetylcholine (ACh) have been compared with those of sodium nitroprusside (SNP) and cromakalim on the rat isolated thoracic aorta. 2. Relaxations produced by ACh were endothelium-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e2bef1a921f91b20590fc28880d56c
https://europepmc.org/articles/PMC1854017/
https://europepmc.org/articles/PMC1854017/
Publikováno v:
Drugs. 36
(+/-) Pinacidil inhibited noradrenaline-induced contractions in rat aorta and portal vein. The spontaneous tone of guinea-pig bronchial and taenia caeci muscles was relaxed and the spontaneous mechanical activity of rat portal vein was abolished. (+/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70e9226ee373fa4908d1f395be0f92d
https://pubmed.ncbi.nlm.nih.gov/2855517
https://pubmed.ncbi.nlm.nih.gov/2855517