Zobrazeno 1 - 10
of 43
pro vyhledávání: '"J. S. R. Gibbs"'
Autor:
J. S. R. Gibbs
Publikováno v:
European Respiratory Review, Vol 16, Iss 102, Pp 8-12 (2007)
Poor survival among patients with untreated pulmonary arterial hypertension (PAH) means that timely and accurate diagnosis is of paramount importance. However, the nonspecific nature of PAH symptoms, which include breathlessness and fatigue, make PAH
Externí odkaz:
https://doaj.org/article/c27995edb2404782bdbced5ccecfddf5
Publikováno v:
European Respiratory Review, Vol 18, Iss 111, Pp 4-6 (2009)
Externí odkaz:
https://doaj.org/article/a60d27abdeab482da072547cb081ac69
Autor:
N Galie, Marius M. Hoeper, Kelly Chin, Loïc Perchenet, O. Sitbon, Stephen C. Mathai, Luke Howard, Vallerie V. McLaughlin, Mylene Stefani, Martin Doelberg, J S R Gibbs, G. Simonneau
Publikováno v:
Pulmonary arterial hypertension: drugs, sox and cytokines.
Introduction and Objectives In the randomized controlled TRITON (NCT02558231) study, both initial triple oral (macitentan, tadalafil, selexipag) and initial double oral (macitentan, tadalafil, placebo) therapy improved pulmonary vascular resistance (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a8c4b903a8d027233fa68efda1bf23e
https://doi.org/10.1136/thorax-2020-btsabstracts.99
https://doi.org/10.1136/thorax-2020-btsabstracts.99
Autor:
Loïc Perchenet, Stephen C. Mathai, O. Sitbon, J S R Gibbs, G. Simonneau, Martin Doelberg, Marius M. Hoeper, Vallerie V. McLaughlin, N Galie, K. Chin, Nicolas Martin
Publikováno v:
European Heart Journal. 41
Introduction Long-term outcomes are important in PAH. Purpose To evaluate the long-term efficacy and safety of initial triple oral therapy with selexipag, macitentan and tadalafil vs initial double oral therapy with macitentan and tadalafil in PAH. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85709419e0343fdcdf88cf13db17c54c
https://doi.org/10.1093/ehjci/ehaa946.2288
https://doi.org/10.1093/ehjci/ehaa946.2288
Autor:
J Afoke, Luke Howard, Prakash P Punjabi, G.S Kanaganayagam, V.D Bruno, J. S. R. Gibbs, R Casula
Publikováno v:
European Heart Journal. 41
Background Primary mitral regurgitation (MR) is one of the most common heart valvular pathologies. However, optimum timing of surgery remains controversial. Purpose To describe changes in cardiopulmonary exercise testing (CPET) parameters after surge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::248400ded1bbad9931fcd7bed5a581ae
https://doi.org/10.1093/ehjci/ehaa946.2003
https://doi.org/10.1093/ehjci/ehaa946.2003
Autor:
Nicholas W. Morrell, Jay Suntharalingam, Marc Humbert, Marta Bleda, Shahin Moledina, Luke Howard, Richard C. Trembath, A. Vonk Noordegraaf, M Jonson, James Lordan, Andrew J. Peacock, Robin Condliffe, J S R Gibbs, Colin Church, Stefan Gräf, Toshner, Wilkins, Paul A. Corris, Charaka Hadinnapola, Allan Lawrie, Simon Holden, Emilia M. Swietlik, Werner Seeger, Gerry Coghlan, Joshua Hodgson, Stephen J. Wort, David G. Kiely, John Wharton, Paul D. Upton, Joanna Pepke-Zaba, Horst Olschewski, Matthias Haimel, R.V. MacKenzie Ross
Publikováno v:
Fundamental mechanisms of pulmonary arterial hypertension.
Introduction A major breakthrough in the understanding the pathobiology of pulmonary arterial hypertension (PAH) was the identification of heterozygous disease-causing mutations in the BMPR2gene. Recently, mutations were also identified in GDF2, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c3686eaab40f0d36a58aabe2c3850f1
https://doi.org/10.1136/thorax-2018-212555.46
https://doi.org/10.1136/thorax-2018-212555.46
Autor:
Loïc Perchenet, N Galie, Martin Doelberg, Nicolas Martin, Stephen C. Mathai, O. Sitbon, J S R Gibbs, K. Chin, Vallerie V. McLaughlin, G. Simonneau, Marius M. Hoeper
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S108
Purpose In TRITON (NCT02558231), initial triple (macitentan, tadalafil, selexipag) and initial double (macitentan, tadalafil, placebo) oral therapy in newly diagnosed PAH patients markedly improved hemodynamic and functional parameters at week 26, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::907a37f92314cb4646ed71421906d8d1
https://doi.org/10.1016/j.healun.2021.01.349
https://doi.org/10.1016/j.healun.2021.01.349
Autor:
Shahin Moledina, Christopher J. Rhodes, J Suntharalingam, Emilia M. Swietlik, Gerry Coghlan, S. Provencher, Andrew J. Peacock, Charaka Hadinnapola, R Condliffe, Carmen M. Treacy, Joanna Pepke-Zaba, Matthew D. Johnson, John Wharton, E. Di Angelantonio, Allan Lawrie, Michael Newnham, James Lordan, Stephen J. Wort, Laura C. Price, Luke S. Howard, David G. Kiely, Eleni Sofianopoulou, Martin R. Wilkins, Stephen Kaptoge, Jennifer M. Martin, Nicholas W. Morrell, Paul A. Corris, R.V. MacKenzie Ross, Matthias Haimel, J S R Gibbs, Mark Toshner, Colin Church, Stefan Gräf
Publikováno v:
Environmental Epidemiology. 3:376
While traffic and air pollution exposure is associated with increased mortality in numerous diseases, its association with disease severity and outcomes in pulmonary arterial hypertension (PAH) remains unknown.Exposure to particulate matter ≤2.5 μ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8ebedc95d274cd2c18d55dec584de4
https://doi.org/10.1097/01.ee9.0000610184.58135.60
https://doi.org/10.1097/01.ee9.0000610184.58135.60
Autor:
Sean Gaine, J S R Gibbs, John G Coghlan, Charlie Elliot, Luke Howard, Martin Johnson, Karen Sheares, James L. Lordan, Stephen J. Wort, Paul A. Corris, David G. Kiely, Andrew J. Peacock, Robin Condliffe, Joanna Pepke-Zaba, Michael A. Gatzoulis, Andrew J. Fisher, Yi Ling
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 186:790-796
Incident pulmonary arterial hypertension was underrepresented in most pulmonary hypertension registries and may have a different disease profile to prevalent disease.To determine the characteristics and outcome of a purely incident, treatment-naive c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497198f6f21dbbc6a940ef7513f7a350
https://doi.org/10.1164/rccm.201203-0383oc
https://doi.org/10.1164/rccm.201203-0383oc
Autor:
Christopher J. Rhodes, J S R Gibbs, J Wharton, A. Vonk-Noordegraaf, L Howard, Martin R. Wilkins
Publikováno v:
Rhodes, C J, Wharton, J, Howard, L, Gibbs, J S R, Vonk Noordegraaf, A & Wilkins, M R 2011, ' Iron deficiency in pulmonary arterial hypertension: a potential therapeutic target ', European Respiratory Journal, vol. 38, no. 6, pp. 1453-1460 . https://doi.org/10.1183/09031936.00037711
European Respiratory Journal, 38(6), 1453-1460. European Respiratory Society
European Respiratory Journal, 38(6), 1453-1460. European Respiratory Society
Iron deficiency is known to be common and detrimental in chronic left heart failure, where parenteral iron treatment has been shown to improve exercise capacity, New York Heart Association functional class and patient wellbeing. There is now increasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b30e1d70a47b194c46eebe4e248fb1d
https://doi.org/10.1183/09031936.00037711
https://doi.org/10.1183/09031936.00037711