Zobrazeno 1 - 6 of 6 pro vyhledávání: '"J. S. Mitcheson"'
1
Comparison of Na+/Ca2+ exchanger current and of its response to isoproterenol between acutely isolated and short-term cultured adult ventricular myocytes
Autor: Jules C. Hancox, J. S. Mitcheson, V. K. Pabbathi, A.K. Hinde, L. A. Arberry, Yin Hua Zhang, L. Perchenet, Allan J. Levi
Publikováno v: Biochemical and Biophysical Research Communications. 297:302-308
The Na(+)/Ca(2+) exchanger protein is present in the cell membrane of many tissue types and plays key roles in Ca(2+) homeostasis, excitation-contraction coupling, and generation of electrical activity in the heart. The use of adult ventricular myocy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798722fee9c8d5aef055bd275be00dbf
https://doi.org/10.1016/s0006-291x(02)02200-3
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3
Role of Intracellular Sodium Overload in the Genesis of Cardiac Arrhythmias
Autor: Frank Christopher Howarth, J V Jones, J Issberner, Stephen J. Evans, Ion A. Hobai, G R Dalton, J S Mitcheson, J C Hancox, Allan J. Levi, J A Bates
Publikováno v: Journal of Cardiovascular Electrophysiology. 8:700-721
A number of clinical cardiac disorders may be associated with a rise of the intracellular Na concentration (Na(i)) in heart muscle. A clear example is digitalis toxicity, in which excessive inhibition of the Na/K pump causes the Na(i) concentration t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6cab7a988352e981f79fd22d43cc21
https://doi.org/10.1111/j.1540-8167.1997.tb01834.x
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4
Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits
Autor: S L, Cockerill, A B, Tobin, I, Torrecilla, G B, Willars, N B, Standen, J S, Mitcheson
Publikováno v: The Journal of physiology. 581(Pt 2)
The human ether-a-go-go related gene (hERG) potassium channel is expressed in a variety of tissues including the heart, neurons and some cancer cells. hERG channels are modulated by several intracellular signalling pathways and these provide importan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::907627ccec13526253079548eccfa55e
https://pubmed.ncbi.nlm.nih.gov/17363390
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5
Molecular biology of K(+) channels and their role in cardiac arrhythmias
Autor: M, Tristani-Firouzi, J, Chen, J S, Mitcheson, M C, Sanguinetti
Publikováno v: The American journal of medicine. 110(1)
The configuration of cardiac action potentials varies considerably from one region of the heart to another. These differences are caused by differential cellular expression of several types of K(+) channel genes. The channels encoded by these genes c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e437b3a190ced884b3f2f1ab06a9ca6f
https://pubmed.ncbi.nlm.nih.gov/11152866
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6
Ion channel and exchange currents in single myocytes isolated from the rabbit atrioventricular node
Autor: J C, Hancox, J S, Mitcheson
Publikováno v: The Canadian journal of cardiology. 13(12)
To review findings from the authors' laboratory in studies of electrophysiological properties of single rod- and spindle-shaped myocytes from rabbit atrioventricular node (AVN).Single cells were isolated from the AVN of the rabbit heart with the use
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca69c81174cdcef69c502a22951a235e
https://pubmed.ncbi.nlm.nih.gov/9444299
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Plný text Recenzováno Digitální knihovna AV ČR
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