Zobrazeno 1 - 3
of 3
pro vyhledávání: '"J. S. Kulesza"'
Preclinical safety evaluation of the nadolol/bendroflumethiazide combination in mice, rats, and dogs
Autor:
A C, Stevens, C H, Keysser, J S, Kulesza, M M, Miller, J L, Myhre, P L, Sibley, Y H, Yoon, G R, Keim
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 4(3 Pt 1)
Nadolol, a beta-adrenergic antagonist, and bendroflumethiazide, a thiazide diuretic, were administered orally alone and in combination to animals in acute and 6-month toxicity studies and in a rat teratology study. The two drugs in combination showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d4439b6731e32c6a5a63481c5433b53
https://pubmed.ncbi.nlm.nih.gov/6745529
https://pubmed.ncbi.nlm.nih.gov/6745529
Publikováno v:
Antimicrobial agents and chemotherapy. 3(6)
Cephradine, a semisynthetic cephalosporin antibiotic, has a low order of oral and parenteral toxicity in animals. The oral LD 50 in mice and rats ranged from 5 to >8 g/kg, and the intraperitoneal LD 50 values in mice and rats were 0.7 to 1.5 g/kg and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7729052f70bf1b1a81c18c33a06fe85
https://pubmed.ncbi.nlm.nih.gov/4790617
https://pubmed.ncbi.nlm.nih.gov/4790617
Publikováno v:
Antibiotics annual. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae7930302a6e932b055261f7daeaaaf1
https://pubmed.ncbi.nlm.nih.gov/13521782
https://pubmed.ncbi.nlm.nih.gov/13521782