Zobrazeno 1 - 10
of 59
pro vyhledávání: '"J. S. Hill Gaston"'
Autor:
Matthew J. Elder, Steve J. Webster, Timothy J. Fitzmaurice, Aran S. D. Shaunak, Martin Steinmetz, Ronnie Chee, Ziad Mallat, E. Suzanne Cohen, David L. Williams, J. S. Hill Gaston, Jane C. Goodall
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Thymic stromal lymphopoietin (TSLP) is a functionally pleotropic cytokine important in immune regulation, and TSLP dysregulation is associated with numerous diseases. TSLP is produced by many cell types, but has predominantly been characterized as a
Externí odkaz:
https://doaj.org/article/d37c0112f5e9441b8aa4a1a774e80bea
Autor:
Matthew J. Elder, Steve J. Webster, Ronnie Chee, David L. Williams, J. S. Hill Gaston, Jane C. Goodall
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Dectin-1/CLEC7A is a pattern recognition receptor that recognizes β-1,3 glucans, and its stimulation initiates signaling events characterized by the production of inflammatory cytokines from human dendritic cells (DCs) required for antifungal immuni
Externí odkaz:
https://doaj.org/article/7b61fa02b4424390890f997b33134bad
Autor:
Claudia Prevosto, M Farooq Usmani, Sarah McDonald, Aleksandra M Gumienny, Tim Key, Reyna S Goodman, J S Hill Gaston, Michael J Deery, Robert Busch
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161011 (2016)
Major histocompatibility complex class I (MHCI) glycoproteins present cytosolic peptides to CD8+ T cells and regulate NK cell activity. Their heavy chains (HC) are expressed from up to three MHC gene loci (human leukocyte antigen [HLA]-A, -B, and -C
Externí odkaz:
https://doaj.org/article/b141584561f949a092063cb993a5045a
Autor:
Reyna S. Goodman, M. Farooq Usmani, Claudia Prevosto, Timothy J. Key, Aleksandra M. Gumienny, J. S. Hill Gaston, Robert Busch, Michael J. Deery, Sarah McDonald
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161011 (2016)
PLoS ONE, Vol 11, Iss 8, p e0161011 (2016)
Major histocompatibility complex class I (MHCI) glycoproteins present cytosolic peptides to CD8+ T cells and regulate NK cell activity. Their heavy chains (HC) are expressed from up to three MHC gene loci (human leukocyte antigen [HLA]-A, -B, and -C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311124daab7054c1db8955b1cf9dec9c
https://www.repository.cam.ac.uk/handle/1810/266404
https://www.repository.cam.ac.uk/handle/1810/266404
Autor:
Steve J, Webster, Lou, Ellis, Louise M, O'Brien, Beatrice, Tyrrell, Timothy J, Fitzmaurice, Matthew J, Elder, Simon, Clare, Ronnie, Chee, J S Hill, Gaston, Jane C, Goodall
Publikováno v:
Microbes and Infection / Institut Pasteur
Protein kinase RNA activated (PKR) is a crucial mediator of anti-viral responses but is reported to be activated by multiple non-viral stimuli. However, mechanisms underlying PKR activation, particularly in response to bacterial infection, remain poo
Autor:
Jackie Shaw, Christoph Renner, Waji Hassan, Robert Landewé, Carmel B. Stober, Aruna S. Malipeddi, Karen Obrenovic, Paul Creamer, Ramesh N. Jois, Katilin DiGleria, Peter Lanyon, Y. Wang, Simon Kollnberger, Leticia Lojo-Oliveira, A. Baratelle, for Assert Go-Raise Investigators, Michele Olds, Claire Sheehy, D. van der Heijde, Michael J. Green, Lotta Utriainen, Charlotte Cavill, Frances Rees, Karen Mills, N. Kerrigan, J. S. Hill Gaston, Claudia Prevosto, M. Mack, J. Braun, Philip S. Helliwell, Sravan Payeli, P. Geusens, R. Inman, Lucy Coates, S. Xu, Sarah McDonald, Paul Bowness, S. Mudivarthy, Emilio Martín-Mola, Kaushik Sanyal, Gordon Taylor, Chandra Chattopadhyay, D. Gladman, A. Beutler, Tim Key, Philip J. Mease, Paul Emery, J. Sieper, Yasser El Miedany, Frederic Lavie, Jonathan Packham, Concepción Castillo-Gallego, B. Dijkmans, Joanna L. Giles, Rebecca Neame, Cynthia Wright, Benoit Guerette, Reyna Goodman, Alessandra De Riva, Ashok K. Bhalla, Miriam García-Arias, David G. I. Scott, M. U. Rahman, Osiris Marroquin, Roman Fischer, Helen Benham, Helen MakIver, Sarah Hailwood, Katsumi Maenaka, N. Goldstein, A Brooksby, Jon Packham, W. Xu, Christopher T. Ritchlin, Deborah Palmer, Ravinder Sandhu, A. Kavanaugh, Iain B. McInnes, Kirsty McHugh, William Tillett, Karl Gaffney, A. Deodhar, N. Vastesaeger, Michael J. Deery, J. Zrubek, Robert Busch, Jane C. Goodall, Neil McHugh, Sonja Kary, P. Mease, Philip G. Conaghan, Hartmut Kupper, G. G. Krueger, Chamaida Plasencia-Rodríguez, Eugenio de Miguel Mendieta, Gamal Ibrahim, Gill Peffers, James Francis, J. Leeder, Carolyn Bell, E. Korendowych, Benedikt M. Kessler, Louise Hamilton, Nicola Erb, Jacqueline Shaw, Margaret Somerville, Karen Walker-Bone, Simon Milling, Laura C. Coates, B. Hsu
Publikováno v:
Rheumatology. 50:iii137-iii145
Background: Sacroiliac joints (SJ) involvement is a distinctive and charasteristic feature of Spondyloarthritis (SpA) and x-ray is the test routinely used to make a diagnosis. However, x-ray reveals late structural damage but cannot detect active inf
Publikováno v:
Molecular Immunology. 48:321-332
Foxp3 is proposed to play a critical role in the development and function of regulatory T cells. Functional and transgenic studies in mice propose Foxp3 as a “regulatory T cell lineage specification factor” but conflicting data exist in humans. E
Publikováno v:
Arthritis & Rheumatism. 60:1647-1656
Objective To analyze the frequency, surface phenotype, and cytokine secretion of CD4+ T cells in peripheral blood mononuclear cells (PBMCs) from patients with ankylosing spondylitis (AS) compared with both healthy control subjects and patients with r
Publikováno v:
Current Immunology Reviews. 5:89-101
Publikováno v:
Annals of the Rheumatic Diseases. 68:1345-1351
Objectives: Interleukin (IL)4+CD8+ regulatory T cells (Treg) obtained from peripheral blood mononuclear cells (PBMCs) from patients with ankylosing spondylitis (AS) by coculture with autologous dendritic cells (DC) have been previously described. In