Zobrazeno 1 - 10
of 28
pro vyhledávání: '"J. S. Graham"'
Autor:
J. S. Graham, J. Kalter, M. H-C. Jin, Jamie E. Elsila, Stergios J. Papadakis, K. R. Turner, L. J. Currano, H. Navid, K. Gerasopoulos, T. M. Kott, R. Walter, B. Tien Street
Publikováno v:
2017 IEEE Aerospace Conference.
We describe experiments conducted to ascertain that a sample collected from a comet can be returned to the surface of the Earth with a minimal loss of scientific information contained in the sample. We consider the sample handling from the point of c
Autor:
Owen Everson, Tram T. Tran, Emily J. S. Graham, Florian Wakenhut, Paul Targett-Adams, Jared Millbank, David M. Beal, Lyn H. Jones, Matthew D. Selby, George M. Burslem, Peter G. Dodd
Publikováno v:
Journal of Chemical Biology. 4:49-53
Small molecule fluorometric boron dipyrromethene probes were developed to bind hepatitis C virus-encoded NS5A protein and aid subcellular distribution studies. These molecules did not co-locate with NS5A, therefore alternative 'silent' azide reporter
Publikováno v:
Wireless Networks. 14:449-464
The most accurate approaches to frequency assignment problems minimize a cost function based on signal-to-interference ratios at points where reception is required. The merits of this approach are counterbalanced by much greater requirements for comp
Publikováno v:
Clinical genetics. 88(3)
The incidence of pancreatic ductal adenocarcinoma (PDAC) is steadily increasing and the annual death-to-incidence ratio approaches one. This is a figure that has not changed for several decades. Surgery remains the only chance of cure; however, only
Autor:
S. Walsh, R Reid, G. Dunbar, J. D. White, J. S. Graham, Boyd K, C. Dick, F. Cowie, S. A. Nowicki
Publikováno v:
Journal of Clinical & Experimental Pathology.
Background and aims: Gastrointestinal Stromal Tumours (GIST) are mesenchymal soft tissue neoplasms which express the c-kit receptor and are exquisitely sensitivity to tyrosine kinase receptor inhibitors such as imatinib. This has significantly improv
Publikováno v:
Journal of Environmental Quality. 25:1048-1053
Persistence and leaching of 14 C-metribuzin [4-amino-6-(1,1-dimethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one] and metabolites were determined in Tanana (loamy, mixed, nonacid Pergelic Cryaquept) and Beales (sandy, mixed Typic Cryochrept) silt loam so
Autor:
David C. Pryde, Chris Pickford, Paul Targett-Adams, Helen Lavender, Mike Westby, Amy Palmer, Stephen M. Shaw, Tram T. Tran, Florian Wakenhut, Blanda Luzia Christa Stammen, Jenny Middleton, Emily J. S. Graham, Philip Brain, Lyn H. Jones
Publikováno v:
Journal of virology. 85(13)
The current standard of care for hepatitis C virus (HCV)-infected patients consists of lengthy treatment with interferon and ribavirin. To increase the effectiveness of HCV therapy, future regimens will incorporate multiple direct-acting antiviral (D
Autor:
Emily J. S. Graham, Mike Westby, Stephen M. Shaw, Jennifer Hammond, Chris Pickford, Rachael Hunt, Paul Targett-Adams
Publikováno v:
Journal of virological methods. 174(1-2)
The current standard of care for patients infected with hepatitis C virus (HCV) is not effective universally and is associated with severe side effects. Direct-acting antiviral molecules have potential to transform treatment of HCV-infected individua
Autor:
Matthew Strawbridge, Emily J. S. Graham, Thierry Guyot, David Hepworth, Mark S. Betson, James Hart, Denise J. Burring, Mark Ian Lansdell
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(18)
The design and synthesis of the first fluorophore-conjugated SGLT2 inhibitors is described. The mode of linking the fluorophore to the SGLT2 pharmacophore was found to be crucial in achieving optimum potency. Superior potency to phlorizin was provide
Publikováno v:
Journal of applied toxicology : JAT. 20
Animal models are employed to investigate mechanisms of injury and to evaluate protective measures against sulfur mustard (HD) exposure. The ability to detect and quantify HD enables the researcher to follow safe procedures in handling skin samples.