Zobrazeno 1 - 10
of 61
pro vyhledávání: '"J. S. Arn"'
Autor:
Nalu Navarro Alvarez, Parsia A. Vagefi, Alexander Y. Zhu, David H. Sachs, J S Arn, Michael Duggan, Ronald S. Arellano, Mark A. Randolph, Christene A. Huang
Publikováno v:
Xenotransplantation. 22:368-378
Background The objective of this study was to investigate the humoral immune response to xenogeneic antigens administered during the fetal state utilizing a baboon-to-pig model. Methods Nine fetuses from an alpha-1,3-galactosyltransferase gene knocko
Autor:
Robert A. Wilkinson, Eric S. Clayman, Shannon G. Pratts, Masayuki Tasaki, J S Arn, Vimukthi Pathiraja, Kazuhiko Yamada, Vincenzo Villani, David H. Sachs, Taylor Cormack, Aseda Tena, Akira Shimizu, Jay A. Fishman, M. Sekijima, Isaac Wamala
Publikováno v:
American Journal of Transplantation. 15:974-983
Previous attempts of α-1,3-galactocyltransferase knockout (GalTKO) pig bone marrow (BM) transplantation (Tx) into baboons have demonstrated a loss of macro-chimerism within 24 h in most cases. In order to achieve improved engraftment with persistenc
Autor:
C. Mallard, Aseda Tena, David H. Sachs, Sharon Germana, Josef Kurtz, Robert J. Hawley, J. R. Dobrinsky, S. L. Terlouw, J. Verstegen, David A. Leonard, J S Arn, Namdori R. Mtango
Publikováno v:
American Journal of Transplantation. 14:2713-2722
Mixed chimerism approaches for induction of tolerance of solid organ transplants have been applied successfully in animal models and in the clinic. However, in xenogeneic models (pig-to-primate), host macrophages participate in the rapid clearance of
Autor:
Vincenzo Villani, Kazuhiko Yamada, David H. Sachs, Joshua Weiner, Nicole Turcotte, Joseph R. Scalea, J S Arn, Pierre Gianello, B. Gillon
Publikováno v:
Transplantation. 98:514-519
BACKGROUND: The clinical significance of antibodies directed against antigens other than major histocompatibility complex (MHC) antigens is poorly understood, and there are few large animal models in which such antibodies can be examined. We studied,
Autor:
Grimus, Sarah1,2,3, Sarangova, Victoria4, Welzel, Petra B.4, Ludwig, Barbara5,6,7,8, Seissler, Jochen9, Kemter, Elisabeth1,2,3,7, Wolf, Eckhard1,2,3,7 ewolf@genzentrum.lmu.de, Ali, Asghar1,2,3
Publikováno v:
Advanced Science. 8/21/2024, Vol. 11 Issue 31, p1-27. 27p.
Autor:
Akira Shimizu, Radbeh Torabi, J S Arn, Kazuhiko Yamada, Taylor Cormack, Vincenzo Villani, Masayuki Tasaki, David H. Sachs, M. Sekijima, Joseph R. Scalea, B. Gillon, S. Moran
Our recent studies in an inbred swine model demonstrated that both peripheral and intra-graft regulatory cells were required for the adoptive transfer of tolerance to a second, naive donor-matched kidney. Here, we have asked whether both peripheral a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2200dbb90035e6428a80832957eb3cb
https://europepmc.org/articles/PMC4718904/
https://europepmc.org/articles/PMC4718904/
HIGHLY DISPARATE XENOGENEIC SKIN GRAFT TOLERANCE INDUCTION BY FETAL PIG THYMUS IN THYMECTOMIZED MICE
Autor:
Kirsten G. Swenson, J S Arn, Gaoping Zhao, M Sykes, Yong Zhao, Jose-Ignacio Rodriguez-Barbosa
Publikováno v:
Transplantation. 72:1608-1615
Background. Highly disparate xenogeneic pig skin graft tolerance and efficient repopulation of mouse CD4 + T cells are achieved in thymectomized (ATX) B6 mice that receive T cell and natural killer (NK) cell depletion by injection of a mixture of mon
Autor:
Megan Sykes, David H. Sachs, Rolf N. Barth, Gaoping Zhao, J S Arn, Jose-Ignacio Rodriguez-Barbosa, Yong Zhao
Publikováno v:
Transplantation. 72:1223-1231
Background Donor-specific xenograft tolerance can be achieved by grafting fetal porcine thymus tissue to thymectomized (ATX) mice treated with natural killer (NK) and T-cell-depleting monoclonal antibodies plus 3 Gy of total body irradiation (TBI). G
Autor:
Jose-Ignacio Rodriguez-Barbosa, M Sykes, Akira Shimizu, David H. Sachs, Yong Zhao, J S Arn, Rolf N. Barth, Kirsten G. Swenson
Publikováno v:
Transplantation. 69:1447-1451
Background. Xenogeneic donor-specific tolerance can be induced by transplanting fetal pig thymus and liver tissue (FP THY/LIV) to thymectomized (ATX), T/NK cell-depleted mice. By using neonatal pig tissue, we hoped to overcome two obstacles that aris
Publikováno v:
Xenotransplantation. 6:201-212
Partially inbred miniature swine have been developed in this laboratory as a large animal model for studies related to transplantation tolerance and as a source of hematopoietic cells and organs for xenotransplantation. The identification of swine CD