Zobrazeno 1 - 4
of 4
pro vyhledávání: '"J. Russell Burley"'
Autor:
Victoria J Mulligan, Toni Cheung, Joseph Russo, Nidhi Kaushal, Nicola Brice, Louise Dickson, Darian Bartkowski, Steven A. Sheardown, Lee A. Dawson, Justin Powell, J Russell Burley, Stephen H Hitchcock, Natalie Hosea, Mark Carlton, Hans H Schiffer, Huikai Sun, Yun Chen, Jason Lawrence, Holger Monenschein, Murphy Sean, Anne Kanta, Xiao Xu, Keith Page
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 377(3)
GPR6 is an orphan G-protein–coupled receptor that has enriched expression in the striatopallidal, indirect pathway and medium spiny neurons of the striatum. This pathway is greatly impacted by the loss of the nigro-striatal dopaminergic neurons in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7699037aeac8e0d7d1449554af6add50
https://pubmed.ncbi.nlm.nih.gov/33795395
https://pubmed.ncbi.nlm.nih.gov/33795395
Autor:
Iain James, Stuart D.C. Ward, Sarah Louise Mellor, Philip J. Birch, Lars J. S. Knutsen, J. Russell Burley, Fiumana Andrea, Jenny Christine Ionix Pharmaceuticals Ltd Gilbert, Nichola Smith, Fleur Radford, Christopher Hobbs, Christopher Geoffrey Earnshaw
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:662-667
A series of new N-type (Cav2.2) calcium channel blockers derived from the ‘hit’ structures 2-(3-bromo-4-fluorophenyl)-3-(2-pyridin-2-ylethyl)thiazolidin-4-one 9 and its 2-[4-(4-bromophenyl)pyridin-3-yl]-3-isobutyl analogue 10 is described. Extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c98d4be131f371a6794ad282459e9f6
https://doi.org/10.1016/j.bmcl.2006.10.098
https://doi.org/10.1016/j.bmcl.2006.10.098
Autor:
Caroline Anne Hick, J. Russell Burley, Iain James, Kathryn Elsegood, Sarah Elizabeth Helen Bowden, Lodewijk V. Dekker, Tadge Szestak, Zoe Daniels, Andy Southan, David Cronk
Publikováno v:
European Journal of Pharmacology. 528:52-58
The tetrodotoxin-resistant voltage-gated sodium channel α-subunit Nav1.8 is expressed in nociceptors and has been implicated in chronic pain. Difficulties of heterologous expression have so far precluded analysis of the pharmacological properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b89d4f4f2b6666df870636972974fa
https://doi.org/10.1016/j.ejphar.2005.10.035
https://doi.org/10.1016/j.ejphar.2005.10.035
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