Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J. Robert Coleman"'
Publikováno v:
Journal of Pathogens, Vol 2014 (2014)
The majority of studies focused on the construction and reengineering of bacterial pathogens have mainly relied on the knocking out of virulence factors or deletion/mutation of amino acid residues to then observe the microbe’s phenotype and the res
Externí odkaz:
https://doaj.org/article/aa789adb642f4266a3336bd0effc37db
Publikováno v:
mBio, Vol 2, Iss 5 (2011)
ABSTRACT The use of pneumococcal capsular polysaccharide (PPS)-based vaccines has resulted in a substantial reduction in invasive pneumococcal disease. However, much remains to be learned about vaccine-mediated immunity, as seven-valent PPS-protein c
Externí odkaz:
https://doaj.org/article/e15ddd6b88b34e1f85a0a35341f83147
Autor:
Lisa M. Runco, J. Robert Coleman
Publikováno v:
Journal of Pathogens, Vol 2011 (2011)
Given the interconnected nature of our world today, emerging pathogens and pandemic outbreaks are an ever-growing threat to the health and economic stability of the global community. This is evident by the recent 2009 Influenza A (H1N1) pandemic, the
Externí odkaz:
https://doaj.org/article/51fe705299704f3f83c286efdcc3e0f8
Autor:
Nusrat Jahan, Katarina Blagovic, Steffen Mueller, J Robert Coleman, Yiwen Zhao, Johanna K Kaufmann
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b3523fe6259349259c468a9e14cac932
Autor:
Marcin Stawowczyk, Yiwen Zhao, Katie Pfeffer, Juliana Tafrova, James Rodriguez, Chen Yang, Nusrat Jahan, Sybil A. Tasker, Steffen Mueller, J. Robert Coleman, Johanna K. Kaufmann
Publikováno v:
Cancer Research. 83:PD2-04
Multiple species of oncolytic viruses (OVs) have been shown to modulate the tumor microenvironment (TME) by increasing immune cell infiltration and activating stimulatory immune responses, leading to the induction of a tumor-specific immune response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088baa19794622b06bf2217a4a780822
https://doi.org/10.1158/1538-7445.sabcs22-pd2-04
https://doi.org/10.1158/1538-7445.sabcs22-pd2-04
Autor:
Charles B Stauft, Chen Yang, J Robert Coleman, David Boltz, Chiahsuan Chin, Anna Kushnir, Steffen Mueller
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223784 (2019)
Currently, influenza vaccine manufacturers need to produce 1-5 x 107 PFU of each vaccine strain to fill one dose of the current live-attenuated-influenza-vaccine (LAIV). To make a single dose of inactivated vaccine (15 ug of each hemagglutinin), the
Externí odkaz:
https://doaj.org/article/73ad1e00cc2342e1a115bbc7b97ebe66
Autor:
Marcin Stawowczyk, Yiwen Zhao, Katie Pfeffer, Juliana Tafrova, Nusrat Jahan, James Rodriguez, Chen Yang, Sybil Tasker, Steffen Mueller, J Robert Coleman, Johanna Kaufmann
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e1d20d5f880faaa483ddc62300f5ea9
https://doi.org/10.1136/jitc-2022-sitc2022.1139
https://doi.org/10.1136/jitc-2022-sitc2022.1139
Autor:
Yiwen Zhao, Nusrat Jahan, Marcin Stawowczyk, Katie Pfeffer, Juliana Tafrova, James Rodriguez, Chen Yang, Sybil A. Tasker, Steffen Mueller, J. Robert Coleman, Johanna K. Kaufmann
Publikováno v:
Cancer Research. 83:689-689
Multiple oncolytic viruses have been shown to induce various beneficial changes in the tumor microenvironment (TME), which ultimately support induction of anti-tumor immune responses. We have previously demonstrated that CodaLytic, a codon-modified i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f34f438c813fa91796a4614e608dd8e9
https://doi.org/10.1158/1538-7445.am2023-689
https://doi.org/10.1158/1538-7445.am2023-689
Autor:
Juliana Tafrova, Steffen Mueller, Sybil A. Tasker, J. Robert Coleman, Marcin Stawowczyk, Katie Pfeffer, Charles B. Stauft, Johanna Kaufmann, Anna Kushnir
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundOncolytic viruses (OVs) of multiple species have been demonstrated to induce beneficial changes in the tumor microenvironment (TME), increasing immune cell infiltration and activating stimulatory immune responses, which ultimately support i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba562964dad1b78b6cee1c8783ff8258
https://doaj.org/article/48c486fc5a694640a8100f05390d164c
https://doaj.org/article/48c486fc5a694640a8100f05390d164c
Autor:
Dimitris Papamichail, Georgios Papamichail, Hongmei Liu, Vitor Machado, J. Robert Coleman, Nathan Gould
Publikováno v:
IEEE/ACM Transactions on Computational Biology and Bioinformatics. 15:452-459
Advances in de novo synthesis of DNA and computational gene design methods make possible the customization of genes by direct manipulation of features such as codon bias and mRNA secondary structure. Codon context is another feature significantly aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b22d2bdf168d426b449eedba366d37f
https://doi.org/10.1109/tcbb.2016.2542808
https://doi.org/10.1109/tcbb.2016.2542808