Zobrazeno 1 - 10
of 74
pro vyhledávání: '"J. Richard Pilsner"'
Autor:
Karolina Nowak, Oladele A. Oluwayiose, Emily Houle, DruAnne L. Maxwell, Savni Sawant, Amanda Paskavitz, Jennifer B. Ford, Lidia Minguez-Alarcon, Antonia M. Calafat, Russ Hauser, J. Richard Pilsner
Publikováno v:
Environment International, Vol 192, Iss , Pp 109049- (2024)
Phthalates are ubiquitous pollutants in the environment; however, the mechanisms of phthalate-associated reproductive disorders in men are not fully understood. The aim of this study is to investigate associations between urinary phthalate metabolite
Externí odkaz:
https://doaj.org/article/a565e9863b014b1abf5c7f9a11e725ea
Autor:
Savni Sawant, Oladele A. Oluwayiose, Karolina Nowak, DruAnne L. Maxwell, Emily Houle, Amanda L. Paskavitz, Hachem Saddiki, Ricardo P. Bertolla, J. Richard Pilsner
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 2, Pp 1567-1578 (2024)
The well-documented relationship between chronological age and the sperm methylome has allowed for the construction of epigenetic clocks that estimate the biological age of sperm based on DNA methylation, which we previously termed sperm epigenetic a
Externí odkaz:
https://doaj.org/article/4b7389771a5543de8fe13462e8e3ff8b
Autor:
DruAnne L. Maxwell, Oladele A Oluwayiose, Emily Houle, Katherine Roth, Karolina Nowak, Savni Sawant, Amanda L. Paskavitz, Wanqing Liu, Katherine Gurdziel, Michael C. Petriello, J. Richard Pilsner
Publikováno v:
Environment International, Vol 186, Iss , Pp 108577- (2024)
Male fertility has been declining worldwide especially in countries with high levels of endocrine disrupting chemicals (EDCs). Per- and polyfluorinated alkyl Substances (PFAS) have been classified as EDCs and have been linked to adverse male reproduc
Externí odkaz:
https://doaj.org/article/abf5efc625984830ac65888d66cf5ec3
Autor:
Oladele A. Oluwayiose, Emily Houle, Brian W. Whitcomb, Alexander Suvorov, Tayyab Rahil, Cynthia K. Sites, Stephen A. Krawetz, Pablo E. Visconti, J. Richard Pilsner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Infertility remains a global health problem with male-factor infertility accounting for around 50% of cases. Understanding the molecular markers for the male contribution of live birth success has been limited. Here, we evaluated the expr
Externí odkaz:
https://doaj.org/article/29384763ed6146b2833afa5f4703227f
Autor:
Oladele A. Oluwayiose, Haotian Wu, Hachem Saddiki, Brian W. Whitcomb, Laura B. Balzer, Nicole Brandon, Alexander Suvorov, Rahil Tayyab, Cynthia K. Sites, Lisa Hill, Chelsea Marcho, J. Richard Pilsner
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Parental age at time of offspring conception is increasing in developed countries. Advanced male age is associated with decreased reproductive success and increased risk of adverse neurodevelopmental outcomes in offspring. Mechanisms for the
Externí odkaz:
https://doaj.org/article/50b7bf75636b4391815a202020e33992
Autor:
Oladele A. Oluwayiose, Chelsea Marcho, Haotian Wu, Emily Houle, Stephen A. Krawetz, Alexander Suvorov, Jesse Mager, J. Richard Pilsner
Publikováno v:
Environment International, Vol 155, Iss , Pp 106693- (2021)
Preconception environmental conditions have been demonstrated to shape sperm epigenetics and subsequently offspring health and development. Our previous findings in humans showed that urinary anti-androgenic phthalate metabolites in males were associ
Externí odkaz:
https://doaj.org/article/d1475a9a8bfd471eae1ef72b990d3320
Autor:
Alexey Stupnikov, Vitaly Bezuglov, Ivan Skakov, Victoria Shtratnikova, J. Richard Pilsner, Alexander Suvorov, Oleg Sergeyev
Publikováno v:
Non-Coding RNA, Vol 8, Iss 3, p 30 (2022)
Transcriptomics analysis of various small RNA (sRNA) biotypes is a new and rapidly developing field. Annotations for microRNAs, tRNAs, piRNAs and rRNAs contain information on transcript sequences and loci that is vital for downstream analyses. Severa
Externí odkaz:
https://doaj.org/article/ef6ce0129814421392235898d1021de3
Autor:
Susan R. Sturgeon, J. Richard Pilsner, Kathleen F. Arcaro, Kaoru Ikuma, Haotian Wu, Soon-Mi Kim, Nayha Chopra-Tandon, Adam R. Karpf, Regina G. Ziegler, Catherine Schairer, Raji Balasubramanian, David A. Reckhow
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Several studies have suggested that global DNA methylation in circulating white blood cells (WBC) is associated with breast cancer risk. Methods To address conflicting results and concerns that the findings for WBC DNA methylation
Externí odkaz:
https://doaj.org/article/5c1f5ef399d04cd88c27d50766796280
Autor:
Oladele A. Oluwayiose, Emily Houle, Brian W. Whitcomb, Alexander Suvorov, Tayyab Rahil, Cynthia K. Sites, Stephen A. Krawetz, Pablo Visconti, J. Richard Pilsner
Publikováno v:
Andrology. 11:677-686
Currently, the precise mechanisms that underline male infertility are still unclear. Accumulating data implicate non-coding RNA cargo of seminal plasma extracellular vesicles due to their association with poor semen quality and higher expression leve
Publikováno v:
Human Reproduction Update. 29:24-44
BACKGROUND Modern reproductive behavior in most developed countries is characterized by delayed parenthood. Older gametes are generally less fertile, accumulating and compounding the effects of varied environmental exposures that are modified by life