Zobrazeno 1 - 10
of 145
pro vyhledávání: '"J. Rennick"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Measuring sub-cellular pH with high accuracy and spatiotemporal resolution remains challenging. Here, Johnston and co-workers develop a pH biosensor that combines the pH dependant fluorescent lifetime of mApple with deep learning to accurately determ
Externí odkaz:
https://doaj.org/article/1627734c9e5446319ae9a57c443160c9
Autor:
Dagmar Roelofs, Katharina S. Schmitz, Geert van Amerongen, Laurine C. Rijsbergen, Brigitta M. Laksono, Anouskha D. Comvalius, Sham Nambulli, Linda J. Rennick, Peter van Run, W. Paul Duprex, Judith M. A. van den Brand, Rik L. de Swart, Rory D. de Vries
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT Raccoons are naturally susceptible to canine distemper virus (CDV) infection and can be a potential source of spill-over events. CDV is a highly contagious morbillivirus that infects multiple species of carnivores and omnivores, resulting in
Externí odkaz:
https://doaj.org/article/876ae783c798400abe51b32523aeac3c
Autor:
Serena L. Y. Teo, Joshua J. Rennick, Daniel Yuen, Hareth Al-Wassiti, Angus P. R. Johnston, Colin W. Pouton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Our understanding of cytosolic delivery is hindered by existing methods for quantification which suffer from being indirect and showing low sensitivity. Here the authors report a SLEEQ (Split Luciferase Endosomal Escape Quantification) assay to asses
Externí odkaz:
https://doaj.org/article/51c2a8863f7b4866907c4bcbaa87460c
Autor:
Laura I. FitzGerald, Luigi Aurelio, Moore Chen, Daniel Yuen, Joshua J. Rennick, Bim Graham, Angus P. R. Johnston
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Determining the trafficking of intracellular material is commonly done by colocalisation analysis using microscopy. Here the authors monitor trafficking of select cargo by measuring the conversion of quenched SNAP-tag substrates by subcellularly-loca
Externí odkaz:
https://doaj.org/article/67585245818b4c449e5738f29dc6b93c
Autor:
Natasha L. Tilston-Lunel, Stephen R. Welch, Sham Nambulli, Rory D. de Vries, Gregory W. Ho, David E. Wentworth, Reed Shabman, Stuart T. Nichol, Christina F. Spiropoulou, Rik L. de Swart, Linda J. Rennick, W. Paul Duprex
Publikováno v:
mSphere, Vol 6, Iss 5 (2021)
Defective interfering (DI) genomes have long been considered inconvenient artifacts that suppressed viral replication in vitro
Externí odkaz:
https://doaj.org/article/cfc5a68afbac41d1a19d0590c6581ed0
Autor:
Rik L. de Swart, Rory D. de Vries, Linda J. Rennick, Geert van Amerongen, Stephen McQuaid, R. Joyce Verburgh, Selma Yüksel, Alwin de Jong, Ken Lemon, D. Tien Nguyen, Martin Ludlow, Albert D. M. E. Osterhaus, W. Paul Duprex
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-11 (2017)
Measles: The efficacy of needle-free vaccine delivery Research shows that measles aerosol vaccination is effective when the vaccine is delivered to the lower respiratory tract. Measles virus is a highly contagious and potentially deadly human pathoge
Externí odkaz:
https://doaj.org/article/0697d6a8f6fd4e159492aab5b1682ba5
Autor:
Danielle E. Anderson, Kristin Pfeffermann, So Young Kim, Bevan Sawatsky, James Pearson, Mikhail Kovtun, David L. Corcoran, Yvonne Krebs, Kristmundur Sigmundsson, Sharon F. Jamison, Zhen Zhen Joanna Yeo, Linda J. Rennick, Lin-Fa Wang, Pierre J. Talbot, W. Paul Duprex, Mariano A. Garcia-Blanco, Veronika von Messling
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Paramyxoviruses and pneumoviruses have similar life cycles and share the respiratory tract as a point of entry. In comparative genome-scale siRNA screens with wild-type-derived measles, mumps, and respiratory syncytial viruses in A549 cells,
Externí odkaz:
https://doaj.org/article/458b77fa67604a6a92aa29f115dcdb71
Autor:
Sham Nambulli, Linda J. Rennick, Andrew S. Acciardo, Natasha L. Tilston-Lunel, Gregory Ho, Nicholas A. Crossland, Kathy Hardcastle, Betsy Nieto, Graeme Bainbridge, Tracey Williams, Claire R. Sharp, W. Paul Duprex
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
Feline morbillivirus (FeMV) is a recently discovered pathogen of domestic cats and has been classified as a morbillivirus in the Paramyxovirus family. We determined the complete sequence of FeMV US5 directly from an FeMV-positive urine sample without
Autor:
Claire R. Sharp, Sham Nambulli, Andrew S. Acciardo, Linda J. Rennick, J. Felix Drexler, Bertus K. Rima, Tracey Williams, W. Paul Duprex
Publikováno v:
Emerging Infectious Diseases, Vol 22, Iss 4, Pp 760-762 (2016)
Externí odkaz:
https://doaj.org/article/db2c419c90344d57a7ab2d2b72fc6459
Autor:
Rory D de Vries, Martin Ludlow, Alwin de Jong, Linda J Rennick, R Joyce Verburgh, Geert van Amerongen, Debby van Riel, Peter R W A van Run, Sander Herfst, Thijs Kuiken, Ron A M Fouchier, Albert D M E Osterhaus, Rik L de Swart, W Paul Duprex
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006371 (2017)
Identification of cellular receptors and characterization of viral tropism in animal models have vastly improved our understanding of morbillivirus pathogenesis. However, specific aspects of viral entry, dissemination and transmission remain difficul
Externí odkaz:
https://doaj.org/article/27efe482118e40d3b683c25478a5e591