Zobrazeno 1 - 10
of 396
pro vyhledávání: '"J. Ratner"'
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Haemophilus influenzae (Hi) is an emerging cause of early onset neonatal sepsis, but mechanisms of transmission are not well understood. We aimed to determine the prevalence of vaginal carriage of Hi in reproductive age women and
Externí odkaz:
https://doaj.org/article/e27aa9f95be84c1c88393c287f415e2b
Autor:
Venkata H. Bhavana, Gideon H. Hillebrand, Kathyayini P. Gopalakrishna, Rebekah A. Rapp, Adam J. Ratner, Hervé Tettelin, Thomas A. Hooven
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Group B Streptococcus (GBS) is a major contributor to sepsis, meningitis, and pneumonia in newborns. Indexed bacterial mutant libraries accelerate pathogenesis research by allowing rapid screening of genes that contribute to disease. In this
Externí odkaz:
https://doaj.org/article/351d6199190c403fb7b28deb2934ab30
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Late-onset disease is the most common clinical presentation of Group B Streptococcus (GBS) infection during infancy, and gastrointestinal (GI) colonization is an important precursor. Previously, we described a murine model of postnatal GBS G
Externí odkaz:
https://doaj.org/article/05ada0355c75415ba60953f96cfec344
Autor:
Felicia Kuperwaser, Gal Avital, Michelle J Vaz, Kristen N Noble, Allison N Dammann, Tara M Randis, David M Aronoff, Adam J Ratner, Itai Yanai
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 3, Pp 1-17 (2023)
Abstract Group B Streptococcus (GBS) is a pathobiont that can ascend to the placenta and cause adverse pregnancy outcomes, in part through production of the toxin β‐hemolysin/cytolysin (β‐h/c). Innate immune cells have been implicated in the re
Externí odkaz:
https://doaj.org/article/dcccaae194b04d62b8e18e9e0822de92
Autor:
Katherine M Laycock, Francia Acosta, Sandra Valera, Ana Villegas, Elia Mejia, Christian Mateo, Rosa Felipe, Anabel Fernández, Megan Job, Sophia Dongas, Andrew P Steenhoff, Adam J Ratner, Sarah Geoghegan
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 9, p e0002281 (2023)
Maternal colonization with Group B Streptococcus (GBS) is an important cause of stillbirth, prematurity, and serious infection and death in infants worldwide. Resource constraints limit prevention strategies in many regions. Maternal GBS vaccines in
Externí odkaz:
https://doaj.org/article/60a0f1e5dd1747d38152d9ca5dcb7388
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Pore-forming toxins (PFTs) are commonly produced by pathogenic bacteria, and understanding them is key to the development of virulence-targeted therapies. Streptococcus agalactiae, or group B Streptococcus (GBS), produces several factors tha
Externí odkaz:
https://doaj.org/article/1626becd9e7c44e6be57905e3fa1811d
Autor:
William D. McCaig, Alexa L. Hodges, Matthew A. Deragon, Robert J. Haluska Jr, Sheila Bandyopadhyay, Adam J. Ratner, Steven L. Spitalnik, Eldad A. Hod, Timothy J. LaRocca
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 3, Pp 496-507 (2019)
Externí odkaz:
https://doaj.org/article/79692d0861fd42469acc10c4c1c25413
Autor:
Kate Clouse, Asem Shehabi, Abel Mani Suleimat, Samir Faouri, Najwa Khuri-Bulos, Abeer Al Jammal, James Chappell, Kimberly B. Fortner, Anna B. Chamby, Tara M. Randis, Adam J. Ratner, David M. Aronoff, Natasha Halasa
Publikováno v:
BMC Pregnancy and Childbirth, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Little is known of the burden of Group B Streptococcus (GBS) colonization among pregnant women in Jordan. We conducted a pilot study to determine the prevalence of GBS among pregnant women in Amman, Jordan, where GBS testing is no
Externí odkaz:
https://doaj.org/article/131588cca0884d07b3a7c54f13f78b20
Autor:
Allison N Dammann, Anna B Chamby, Andrew J Catomeris, Kyle M Davidson, Hervé Tettelin, Jan-Peter van Pijkeren, Kathyayini P Gopalakrishna, Mary F Keith, Jordan L Elder, Adam J Ratner, Thomas A Hooven
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009116 (2021)
Streptococcus agalactiae (group B Streptococcus; GBS) remains a dominant cause of serious neonatal infections. One aspect of GBS that renders it particularly virulent during the perinatal period is its ability to invade the chorioamniotic membranes a
Externí odkaz:
https://doaj.org/article/3493e7f3e0ba42799bba78ade439f8e2
Autor:
Sarah Geoghegan, Francia Acosta, Laura C. Stephens, Hanah Gillan, Sandra Valera, Richard J. Drew, Maeve Eogan, Adam J. Ratner, Andrew P. Steenhoff, Karina M. Butler, Kristen A. Feemster
Publikováno v:
Vaccine. 41:2013-2021