Zobrazeno 1 - 10
of 20
pro vyhledávání: '"J. R. Yankaskas"'
Publikováno v:
Methods in molecular medicine. 7
Cystic fibrosis (CF) is a recessive genetic disease that affects the regulation of ion transport in the epithelia of various organs in the body including the lungs, pancreas, intestine, salivary glands, and urogenital tract. The protein encoded by th
Publikováno v:
American Journal of Physiology-Cell Physiology. 271:C188-C193
Cystic fibrosis (CF) reflects the loss of adenosine 3',5'-cyclic monophosphate (cAMP)-regulated Cl- secretion consequent to mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. In humans, but not mice, with CF, the diseas
Publikováno v:
American Journal of Physiology-Cell Physiology. 268:C708-C712
Defective adenosine 3',5'-cyclic monophosphate (cAMP)-mediated Cl- transport in cystic fibrosis (CF) reflects defects in the cystic fibrosis transmembrane conductance regulator (CFTR). A moderate level of CFTR mRNA expression has been found in rodent
Publikováno v:
American Journal of Rhinology. 4:45-49
Epithelial cells isolated from nasal polyps and inferior turbinates from patients with cystic fibrosis (CF) and without CF were studied on permeable collagen matrices. Transepithelial potential difference and resistance were measured daily, and the e
Autor:
J R, Yankaskas, G B, Mallory
Publikováno v:
Chest. 113(1)
The first successful heart-lung and lung transplant operations in cystic fibrosis (CF) patients were performed in 1983 and 1987, respectively. Lung transplantation is now available at dozens of centers in North America, Europe, and Australia. Recent
Publikováno v:
Seminars in respiratory infections. 11(4)
Since 1990, there have been an increasing number of reports of nontuberculous mycobacteria (NTM) recovered from lower respiratory tract specimens of patients with cystic fibrosis (CF) lung disease. The eight reports from series of prospectively scree
Autor:
James D. Crapo, Ismo Virtanen, J R Yankaskas, Ling-Yi Chang, Bor-Hwang Kang, Vuokko L. Kinnula, A Linnala
Publikováno v:
American journal of respiratory cell and molecular biology. 11(5)
Antioxidant enzymes located in the bronchial epithelium can be expected to be important in protecting these cells against both endogenous and exogenous oxidants. In this study, human bronchial epithelial cells were isolated and cultured from specimen
Publikováno v:
Clinical chemistry. 40(10)
A case of adenocarcinoma of the pancreas and mild lung disease in a 39-year-old man homozygous for the delta F508 cystic fibrosis mutation is presented. Cystic fibrosis is the most common lethal genetic disease in Caucasians, and is most commonly ass
Autor:
P A, Flume, T M, Egan, J H, Westerman, L J, Paradowski, J R, Yankaskas, F C, Detterbeck, M R, Mill
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 13(1 Pt 1)
As lung transplantation has become more successful, the selection criteria have broadened; however, some relative contraindications to lung transplantation are controversial. Some programs consider mechanical ventilation to be a major contraindicatio
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 4(10)
Retinoic acid (RA) and nuclear retinoic acid receptors (RARs) have been implicated in a variety of human malignancies including lung cancer, and RA has been proposed as a chemopreventive agent for bronchogenic carcinoma. Normal human tracheobronchial