Výsledky vyhledávání - "J. R. SHAVER"

Effects of inflammation and acute beta-agonist inhalation on beta 2-AR signaling in human airways

Autor: James E. Fish, Raymond B. Penn, M. Pollice, Stephen P. Peters, James Zangrilli, J. R. Shaver, J. L. Benovic

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 271:L601-L608

Although alterations in beta 2-adrenergic receptor (AR) responsiveness may in part explain reports linking deterioration of asthma control with beta-agonist treatment of asthmatics, few data exist on beta 2-AR regulation in human airway cells. We hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d5e75913696eb017d802f9cc907ec3
https://doi.org/10.1152/ajplung.1996.271.4.l601

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IL-1β RELEASE FROM CULTURED BRONCHIAL EPITHELIAL CELLS AND BRONCHOALVEOLAR LAVAGE CELLS FROM ALLERGIC AND NORMAL HUMANS FOLLOWING SEGMENTAL CHALLENGE WITH RAGWEED

Autor: James Zangrilli, J. R. Shaver, Stephen P. Peters, Annette T. Hastie, M. Pollice, K. B. Everts, James E. Fish, Seung Kil Cho

Publikováno v: Cytokine. 8:730-738

This work investigated whether interleukin 1 beta (IL-1 beta) release from epithelial cells is modulated by antigen challenge in vivo, and inflammatory cells in vitro. Bronchial epithelial cells were obtained before and after segmental allergen chall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a5017679eed8ace081160a72165406
https://doi.org/10.1006/cyto.1996.0097

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HSP27 elevated in mild allergic inflammation protects airway epithelium from H2SO4 effects

Autor: James Zangrilli, J. R. Shaver, K. B. Everts, James E. Fish, Annette T. Hastie, Stephen P. Peters, M. Pollice

Publikováno v: The American journal of physiology. 273(2 Pt 1)

Inflammation in allergic individuals is hypothesized to elevate stress proteins [heat shock proteins (HSP)] in airway epithelium, which may protect cells from further adverse conditions. Allergic, either asthmatic or not, and normal volunteers partic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4bb4518c202b1f75c21b5a1fa18536
https://pubmed.ncbi.nlm.nih.gov/9277453

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Beta 2-agonist-elevated stress response in human bronchial epithelial cells in vivo and in vitro

Autor: Rosemary Cirelli, James E. Fish, Annette T. Hastie, M. Pollice, Stephen P. Peters, K. B. Everts, James Zangrilli, J. R. Shaver

Publikováno v: Lung. 175(5)

Recent studies report high baseline levels of stress (heat shock) proteins in bronchial epithelial cells from asthmatic individuals. The promoter of the gene encoding the 72-kDa heat shock protein has an element responsive to cAMP, which may be affec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544b3eeedb0540d56c0b18461bdd7eb9
https://pubmed.ncbi.nlm.nih.gov/9270986

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Pulmonary inflammation after segmental ragweed challenge in allergic asthmatic and nonasthmatic subjects

Autor: Gregory C. Kane, James E. Fish, Stephen P. Peters, Seung Kil Cho, J. R. Shaver, M. Pollice, J. J. O'connor

Publikováno v: American journal of respiratory and critical care medicine. 152(4 Pt 1)

Inflammatory reactions in the airways are thought to play an important role in asthma pathogenesis. The goal of this work was to test prospectively the hypothesis that the pulmonary inflammatory response to segmental antigen challenge is greater in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5719463fc3f2d9d6b23872bd68fcd5
https://pubmed.ncbi.nlm.nih.gov/7551369

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