Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J. R. S. Arch"'
Autor:
Edward T. Wargent, Malgorzata A. Kępczyńska, Claire J. Stocker, Jacqueline F. O’Dowd, Michael A. Cawthorne, J. R. S. Arch
Publikováno v:
Journal of developmental origins of health and disease. 4(6)
An infant's early developmental environment plays a pivotal role in the programming of its physiological phenotype. The identification of the factors in the maternal environment that mediate the effects of maternal obesity and diet is essential to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fce79bb4bc9c916a972b9efe6cedc65
https://pubmed.ncbi.nlm.nih.gov/24924228
https://pubmed.ncbi.nlm.nih.gov/24924228
Publikováno v:
Hormone and Metabolic Research. 33:480-485
Peptides derived from pro-opiomelanocortin, including alpha-MSH and ACTH, play important roles in the regulation of feeding. We investigated the central effect of ACTH 1-39 (ACTH) and peptides derived from the N-terminus (ACTH 1-10, Acetyl-ACTH 1-13-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af234b12bce0e5ab0c6bef2f6c04d51
https://doi.org/10.1055/s-2001-16941
https://doi.org/10.1055/s-2001-16941
Publikováno v:
Journal of the Ghana Science Association; Vol 12, No 2 (2010)
β2-adrenoceptors activated by adrenaline can also couple to both Gs and Gi proteins. The former is associated with an increase in cAMP to illicit the effect of the catecholamine. In the later, β2-AR induces PKA-catalysed phosphorylation of the rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030a39d2dac7c76ea50874c5d507c13d
https://doi.org/10.4314/jgsa.v12i2.62814
https://doi.org/10.4314/jgsa.v12i2.62814
Autor:
Edward T. Wargent, Robert A. Ngala, J. R. S. Arch, Matthew V. Sennitt, M. Cawthorne, Claire J. Stocker
Publikováno v:
Journal of the Ghana Science Association; Vol 12, No 1 (2010)
The peroxisome proliferator-activated receptors of the nuclear receptor superfamily are het-erodimers with the 9-cis retinoic acid receptor and bind to specific peroxisome proliferators re-sponse elements to regulate the transcription of their target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d869715dba25eb7912c2f2226d172441
https://www.ajol.info/index.php/jgsa/article/view/56810
https://www.ajol.info/index.php/jgsa/article/view/56810
Publikováno v:
The American Journal of Clinical Nutrition. 55:252S-257S
BRL 35135, via its active deesterified metabolite BRL 37344, is a potent example of a new group of beta-adrenoceptor agonists that stimulate selectively a novel beta adrenoceptor that was originally shown to be present in brown adipose tissue in rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5d5469e99d6936cf25dd5135372e0d
https://doi.org/10.1093/ajcn/55.1.252s
https://doi.org/10.1093/ajcn/55.1.252s
Publikováno v:
Journal of the Ghana Science Association; Vol 11, No 1 (2009)
Recent studies suggest that type 2 diabetes, which is usually associated with obesity, also involves defective energy expenditure, specifically fat oxidation in skeletal muscle. Skeletal muscle is a major site of fatty acid and glucose disposal. β-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0beddd532291d36c904aea48c2942e6
https://www.ajol.info/index.php/jgsa/article/view/47003
https://www.ajol.info/index.php/jgsa/article/view/47003
Publikováno v:
British journal of pharmacology. 155(3)
Picomolar concentrations of the beta3-adrenoceptor agonist BRL37344 stimulate 2-deoxyglucose uptake in soleus muscle via undefined receptors. Higher concentrations alter uptake, apparently via beta2-adrenoceptors. Effects of BRL37344 and beta2-adreno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80cddb68d1e78dd06c526d07a805fb8c
https://pubmed.ncbi.nlm.nih.gov/18552870
https://pubmed.ncbi.nlm.nih.gov/18552870
Autor:
J. R. S. Arch
Publikováno v:
Journal of endocrinological investigation. 25(10)
Many genetic manipulations have created models of obesity, leanness or resistance to dietary obesity in mice, often providing insights into molecular mechanisms that affect energy balance, and new targets for anti-obesity drugs. Since many genes can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb35745bb9b72b99595d011c3735797c
https://pubmed.ncbi.nlm.nih.gov/12508949
https://pubmed.ncbi.nlm.nih.gov/12508949
Autor:
J. R. S. Arch
Publikováno v:
Diabetologia. 50:239-240
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dcf083a1cd4034415904f94d4d93459
https://doi.org/10.1007/s00125-006-0523-x
https://doi.org/10.1007/s00125-006-0523-x
Publikováno v:
Agents and actions. 39(3-4)
In rats, Sephadex treatment on days 0, 2 and either 4 or 5 resulted in a blood and lung eosinophilia, an increase in lung cell fragility, an increase in the functional activity of peritoneal eosinophils in vitro and a sustained increased responsivene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5808d0d03a4229d064e220265c8c47fd
https://pubmed.ncbi.nlm.nih.gov/7508178
https://pubmed.ncbi.nlm.nih.gov/7508178